44 pitchers are tied for the most losses in a game with 2+ RBIs, with 1 game. The first three are Wade Miley on September 1, 2021, Lucas Giolito on September 1, 2019 and Merrill Kelly on July 23, 2019.

Interpreted as:

most losses by a player in a regular-season game with 2 or more rbis

	NAME	L	RBI	DATE	TM		OPP	DEC	W	L%	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP
1	Wade Miley W. Miley	1	2	9/1/2021	CIN	vs	STL	L	0	1.000	1	11.25	2	0	0	0	4.0	12	5	5	3	1	0	0	0	23	0
2	Lucas Giolito L. Giolito	1	2	9/1/2019	CWS	@	ATL	L	0	1.000	1	6.00	7	0	0	0	6.0	4	4	4	2	1	0	0	0	23	0
3	Merrill Kelly M. Kelly	1	2	7/23/2019	ARI	vs	BAL	L	0	1.000	1	27.00	4	0	0	0	2.1	8	7	7	3	0	0	0	0	15	0
4	Vince Velasquez V. Velasquez	1	2	6/28/2019	PHI	@	MIA	L	0	1.000	1	8.31	6	0	0	0	4.1	6	4	4	1	2	0	0	0	21	0
5	Tanner Roark T. Roark	1	2	6/1/2019	CIN	vs	WSH	L	0	1.000	1	6.00	6	0	0	0	6.0	6	4	4	2	1	0	0	0	25	0
6	Madison Bumgarner M. Bumgarner	1	2	4/2/2019	SFG	@	LAD	L	0	1.000	1	0.00	4	0	0	0	6.0	5	0	5	1	2	0	0	0	25	0
7	Chris Stratton C. Stratton	1	3	9/19/2018	SFG	@	SDP	L	0	1.000	1	15.00	2	0	0	0	3.0	6	5	5	1	1	0	0	0	16	0
8	Wei-Yin Chen W. Chen	1	2	5/31/2018	MIA	@	SDP	L	0	1.000	1	21.60	4	0	0	0	1.2	4	4	4	1	2	0	0	0	11	0
9	Travis Wood T. Wood	1	2	9/5/2017	SDP	vs	STL	L	0	1.000	1	27.00	1	0	0	0	2.0	7	6	7	2	1	0	0	0	15	0
10	Clayton Richard C. Richard	1	2	8/27/2017	SDP	@	MIA	L	0	1.000	1	6.43	7	0	0	0	7.0	8	5	5	1	2	0	0	1	30	1
11	Carlos Rodón C. Rodón	1	2	7/25/2017	CWS	@	CHC	L	0	1.000	1	9.00	11	0	0	0	4.0	7	4	4	1	3	0	0	0	22	0
12	Jaime Garcia J. Garcia	1	2	7/5/2017	ATL	vs	HOU	L	0	1.000	1	7.50	5	0	0	0	6.0	10	5	5	0	0	0	0	0	27	0
13	Ben Lively B. Lively	1	2	6/24/2017	PHI	@	ARI	L	0	1.000	1	6.75	0	0	0	0	5.1	7	4	5	1	0	0	0	0	24	0
14	Matt Cain M. Cain	1	2	6/22/2017	SFG	@	ATL	L	0	1.000	1	15.75	1	0	0	0	4.0	10	7	7	3	0	0	0	0	22	0
15	Jake Arrieta J. Arrieta	1	2	6/17/2017	CHC	@	PIT	L	0	1.000	1	3.86	7	0	0	0	4.2	4	2	3	1	2	1	0	1	22	2
16	Jeff Samardzija J. Samardzija	1	2	6/16/2017	SFG	@	COL	L	0	1.000	1	12.00	4	0	0	0	6.0	11	8	8	2	1	0	0	0	29	0
17	R.A. Dickey	1	2	4/8/2017	ATL	@	PIT	L	0	1.000	1	4.76	4	0	0	0	5.2	9	3	6	0	4	0	0	1	30	1
18	Ryan Vogelsong R. Vogelsong	1	2	9/3/2015	SFG	@	COL	L	0	1.000	1	21.00	1	0	0	0	3.0	11	7	8	1	0	0	0	0	20	0
19	Matt Harvey M. Harvey	1	2	7/20/2015	NYM	@	WSH	L	0	1.000	1	2.57	3	0	0	0	7.0	4	2	5	0	4	0	0	0	30	0
20	Michael Lorenzen M. Lorenzen	1	2	6/11/2015	CIN	@	CHC	L	0	1.000	1	10.38	6	0	0	0	4.1	5	5	6	2	3	1	0	1	22	1
21	Madison Bumgarner M. Bumgarner	1	2	9/23/2014	SFG	@	LAD	L	0	1.000	1	4.91	5	0	0	0	7.1	6	4	4	3	0	1	0	0	28	0
22	Jerome Williams J. Williams	1	2	9/10/2014	PHI	vs	PIT	L	0	1.000	1	7.20	8	0	0	0	5.0	7	4	4	2	1	2	0	0	25	0
23	Scott Feldman S. Feldman	1	2	5/24/2013	CHC	@	CIN	L	0	1.000	1	8.44	5	0	0	0	5.1	7	5	5	2	1	0	0	0	24	1
24	Randy Wolf R. Wolf	1	2	8/3/2012	MIL	@	STL	L	0	1.000	1	8.44	2	0	0	0	5.1	9	5	5	0	1	0	0	0	25	1
25	Paul Maholm P. Maholm	1	2	6/23/2012	CHC	@	ARI	L	0	1.000	1	16.20	0	0	0	0	3.1	9	6	7	1	3	1	0	0	24	0