Between the 2006 and 2011 seasons, the New York Yankees had the most wins by a team, with 575 wins.

Interpreted as:

most MLB team regular-season wins from 2006 to 2011

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	575	397	.592	972	33,685	5,328	9,317	1,809	159	1,258	5,129	3,773	431	6,347	741	218	38,371	15,218	3,226	206	276	216	840	.277	.354	.452	.806
2	Phillies	558	414	.574	972	33,622	4,861	8,782	1,771	225	1,186	4,652	3,541	442	6,768	689	142	38,224	14,561	3,182	357	262	377	666	.261	.337	.433	.770
3	Red Sox	551	421	.567	972	33,703	5,097	9,242	2,077	166	1,157	4,859	3,831	367	6,534	563	180	38,370	15,122	3,400	150	319	293	832	.274	.352	.449	.800
4	Angels	546	426	.562	972	33,326	4,584	8,964	1,765	163	924	4,360	2,929	278	5,994	803	327	37,052	13,827	2,852	230	289	249	791	.269	.331	.415	.745
5	Tigers	519	454	.533	973	33,786	4,811	9,227	1,789	232	1,084	4,607	3,083	286	6,667	416	184	37,668	14,732	3,105	250	263	222	783	.273	.337	.436	.773
6	Cardinals	514	457	.529	971	33,226	4,513	8,987	1,741	135	971	4,288	3,225	312	5,862	399	208	37,452	13,911	2,847	428	261	395	853	.270	.338	.419	.757
7	Dodgers	511	460	.526	971	33,202	4,346	8,825	1,639	218	801	4,125	3,293	289	6,194	725	280	37,484	13,303	2,658	422	278	358	774	.266	.335	.401	.735
8	Twins	507	467	.521	974	33,428	4,565	9,057	1,694	225	789	4,307	3,115	255	5,726	560	213	37,342	13,568	2,708	237	307	250	875	.271	.335	.406	.741
9	Rangers	507	465	.522	972	33,762	4,978	9,241	1,905	178	1,152	4,729	3,061	280	6,661	637	203	37,647	14,958	3,235	244	300	200	755	.274	.336	.443	.779
10	Braves	501	471	.515	972	33,406	4,526	8,801	1,812	147	989	4,325	3,418	274	6,805	372	191	37,776	13,874	2,948	441	237	296	802	.263	.335	.415	.750
11	Brewers	501	471	.515	972	33,085	4,537	8,593	1,785	193	1,158	4,351	3,190	435	7,103	518	201	37,329	14,238	3,136	350	269	284	699	.260	.330	.430	.761
12	Mets	500	472	.514	972	33,287	4,482	8,813	1,761	234	880	4,244	3,314	288	6,184	866	240	37,657	13,682	2,875	454	314	356	714	.265	.334	.411	.745
13	White Sox	497	476	.511	973	33,100	4,502	8,649	1,597	110	1,176	4,321	3,050	398	6,154	592	303	37,059	13,994	2,883	249	262	178	825	.261	.329	.423	.751
14	Blue Jays	497	475	.511	972	33,385	4,572	8,742	1,938	151	1,142	4,380	3,112	317	6,264	464	177	37,268	14,408	3,231	168	286	186	795	.262	.328	.432	.760
15	Rays	495	477	.509	972	32,945	4,557	8,439	1,707	216	1,088	4,343	3,497	347	7,368	928	320	37,266	13,842	3,011	193	284	184	628	.256	.331	.420	.751
16	Rockies	488	485	.502	973	33,282	4,729	8,846	1,792	262	1,014	4,496	3,553	326	7,221	649	256	37,938	14,204	3,068	499	278	298	704	.266	.340	.427	.767
17	Giants	485	486	.499	971	33,020	3,993	8,426	1,716	223	793	3,764	2,805	292	6,221	503	215	36,782	12,967	2,732	409	256	336	807	.255	.317	.393	.710
18	Cubs	477	493	.492	970	33,365	4,369	8,813	1,816	187	959	4,145	3,027	301	6,791	474	204	37,309	13,880	2,962	382	234	231	777	.264	.329	.416	.745
19	Diamondbacks	477	495	.491	972	32,911	4,369	8,342	1,836	241	1,015	4,192	3,314	310	7,439	564	213	37,133	13,705	3,092	329	269	281	650	.253	.325	.416	.742
20	Padres	476	497	.489	973	33,032	4,005	8,200	1,632	193	850	3,815	3,264	297	7,277	590	195	37,249	12,768	2,675	390	266	278	711	.248	.319	.387	.706
21	Reds	474	498	.488	972	33,240	4,434	8,568	1,690	133	1,137	4,237	3,298	359	7,027	592	244	37,608	13,935	2,960	455	256	276	677	.258	.329	.419	.748
22	Athletics	474	497	.488	971	33,012	4,225	8,367	1,694	141	829	4,010	3,451	294	6,522	607	190	37,247	12,830	2,664	181	309	132	816	.253	.327	.389	.715
23	Marlins	472	499	.486	971	33,239	4,434	8,609	1,815	200	1,051	4,212	3,185	394	7,797	553	222	37,479	13,977	3,066	407	254	277	642	.259	.329	.421	.749
24	Indians	469	503	.483	972	33,330	4,609	8,745	1,889	150	988	4,397	3,327	447	7,283	468	199	37,592	13,898	3,027	211	277	226	733	.262	.335	.417	.752
25	Astros	447	524	.460	971	33,063	4,039	8,501	1,683	164	853	3,864	2,845	302	6,349	589	234	36,889	13,071	2,700	441	238	234	774	.257	.320	.395	.715