Since 2006, the Los Angeles Dodgers have the most wins by a team, with 1,819 wins.

Interpreted as:

most MLB regular-season wins by team since 2006

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Dodgers	1,819	1,319	.580	3,138	106,607	14,801	27,495	5,457	544	3,593	14,122	11,034	1,178	23,794	1,879	640	120,586	44,819	9,594	892	875	839	2,287	.258	.332	.420	.752
2	Yankees	1,798	1,340	.573	3,138	106,784	15,681	27,531	5,169	401	4,303	15,021	11,455	1,200	24,098	1,918	566	120,771	46,411	9,873	440	892	545	2,460	.258	.334	.435	.769
3	Red Sox	1,686	1,452	.537	3,138	108,699	15,671	28,907	6,474	481	3,630	14,908	10,815	1,159	24,208	1,817	556	121,935	47,233	10,585	359	903	713	2,483	.266	.336	.435	.771
4	Cardinals	1,682	1,453	.537	3,135	106,329	14,188	27,455	5,402	437	3,301	13,518	10,167	1,285	23,039	1,440	597	119,547	43,634	9,140	930	836	762	2,445	.258	.328	.410	.738
5	Braves	1,657	1,479	.528	3,136	106,932	14,357	27,391	5,494	440	3,548	13,740	10,432	1,033	24,780	1,484	575	120,068	44,409	9,482	929	742	755	2,351	.256	.326	.415	.741
6	Rays	1,650	1,489	.526	3,139	106,208	14,051	26,559	5,331	589	3,523	13,377	10,499	1,265	26,044	2,418	863	119,240	43,637	9,443	428	840	465	2,107	.250	.323	.411	.733
7	Brewers	1,644	1,495	.524	3,139	106,006	14,205	26,609	5,301	526	3,694	13,563	10,346	1,310	25,805	2,241	701	119,277	44,044	9,521	856	759	658	2,296	.251	.323	.415	.739
8	Guardians	1,638	1,497	.522	3,135	106,331	14,217	26,978	5,655	467	3,280	13,552	10,306	1,238	23,627	2,026	629	119,365	43,407	9,402	583	907	597	2,267	.254	.324	.408	.733
9	Phillies	1,624	1,514	.518	3,138	107,121	14,296	27,054	5,341	616	3,590	13,664	10,157	1,231	24,846	2,007	507	120,094	44,397	9,547	834	751	789	2,134	.253	.322	.414	.737
10	Astros	1,599	1,537	.510	3,136	106,636	14,059	27,216	5,420	437	3,567	13,431	9,746	1,124	23,544	1,828	698	119,037	44,211	9,424	719	812	521	2,470	.255	.322	.415	.736
11	Blue Jays	1,597	1,541	.509	3,138	106,948	14,639	27,339	5,745	385	3,926	14,010	10,128	1,044	23,133	1,499	537	119,385	45,632	10,056	450	815	414	2,511	.256	.324	.427	.750
12	Mets	1,588	1,550	.506	3,138	106,408	13,881	26,801	5,319	528	3,384	13,286	10,265	1,327	23,898	1,945	592	119,691	43,328	9,231	885	806	775	2,293	.252	.323	.407	.730
13	Angels	1,586	1,552	.505	3,138	106,479	14,122	27,047	5,170	474	3,469	13,455	9,558	1,142	23,499	1,985	756	118,562	43,572	9,113	535	848	636	2,432	.254	.320	.409	.729
14	Cubs	1,585	1,551	.505	3,137	106,446	14,067	26,773	5,404	574	3,473	13,388	10,265	1,299	25,481	1,695	668	119,573	43,744	9,451	818	745	651	2,253	.252	.323	.411	.734
15	Giants	1,585	1,552	.505	3,137	106,574	13,227	26,723	5,347	662	2,858	12,574	9,563	1,014	23,759	1,458	575	118,871	41,968	8,867	859	861	748	2,398	.251	.316	.394	.710
16	Rangers	1,563	1,576	.498	3,139	107,185	14,819	27,534	5,403	486	3,691	14,094	9,621	1,141	24,403	2,093	705	119,361	44,982	9,580	559	855	495	2,192	.257	.322	.420	.742
17	Tigers	1,542	1,592	.492	3,134	107,380	14,080	27,874	5,373	698	3,287	13,496	9,350	963	24,680	1,325	550	118,982	44,504	9,358	467	822	531	2,405	.260	.322	.414	.737
18	Twins	1,541	1,599	.491	3,140	107,276	14,397	27,509	5,494	557	3,338	13,686	10,092	1,103	23,866	1,548	579	119,813	44,131	9,389	486	856	529	2,380	.256	.324	.411	.736
19	Mariners	1,540	1,598	.491	3,138	106,554	13,257	26,286	4,930	402	3,417	12,632	9,406	1,230	24,927	1,906	665	118,441	42,271	8,749	518	733	506	2,206	.247	.313	.397	.710
20	Athletics	1,535	1,602	.489	3,137	106,216	13,724	26,049	5,353	457	3,382	13,068	10,479	1,090	24,331	1,674	517	119,023	42,462	9,192	407	831	380	2,409	.245	.317	.400	.717
21	Padres	1,524	1,615	.486	3,139	105,549	13,021	25,777	5,029	540	3,096	12,388	10,033	1,006	25,227	1,992	653	118,307	41,174	8,665	936	783	620	2,193	.244	.314	.390	.704
22	Diamondbacks	1,515	1,623	.483	3,138	106,808	14,266	26,884	5,632	771	3,354	13,599	10,304	1,069	25,122	1,919	629	119,926	44,120	9,757	864	881	701	2,195	.252	.321	.413	.734
23	Reds	1,497	1,641	.477	3,138	106,052	13,777	26,444	5,164	476	3,551	13,147	10,166	1,314	25,233	2,043	746	119,322	43,213	9,191	1,019	771	655	2,183	.249	.321	.407	.728
24	Nationals	1,495	1,641	.477	3,136	106,056	13,718	26,938	5,369	498	3,218	13,051	10,063	1,170	24,166	2,023	706	119,060	42,957	9,085	960	811	678	2,354	.254	.323	.405	.728
25	Orioles	1,453	1,684	.463	3,137	107,448	13,958	27,333	5,331	384	3,754	13,358	8,935	1,087	24,179	1,521	542	118,672	44,694	9,469	427	775	424	2,349	.254	.316	.416	.732