Since 2022, the Los Angeles Dodgers have the most wins by a team, with 402 wins.

Interpreted as:

most MLB regular-season wins by team since 2022

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Dodgers	402	246	.620	648	22,053	3,420	5,648	1,177	98	938	3,295	2,433	261	5,422	427	91	25,005	9,835	2,213	31	227	117	390	.256	.334	.446	.780
2	Astros	371	276	.573	647	21,996	2,990	5,602	1,075	63	808	2,870	1,997	270	4,897	368	106	24,480	9,227	1,946	51	166	78	498	.255	.322	.419	.742
3	Braves	370	278	.571	648	22,095	3,164	5,619	1,107	68	953	3,044	2,068	242	5,619	370	103	24,586	9,721	2,128	27	154	58	448	.254	.323	.440	.763
4	Yankees	369	279	.569	648	21,666	3,144	5,238	944	58	984	3,016	2,488	221	5,607	424	127	24,607	9,250	1,986	44	188	127	482	.242	.324	.427	.750
5	Phillies	368	280	.568	648	22,088	3,105	5,659	1,099	106	835	2,993	2,060	243	5,551	518	114	24,607	9,475	2,040	48	168	77	428	.256	.324	.429	.753
6	Brewers	368	280	.568	648	21,785	3,036	5,343	1,022	84	727	2,891	2,329	257	5,601	606	153	24,590	8,714	1,833	59	160	74	455	.245	.323	.400	.723
7	Padres	354	294	.546	648	21,819	2,919	5,459	1,061	68	700	2,790	2,195	236	4,876	412	112	24,531	8,756	1,829	115	166	76	465	.250	.323	.401	.724
8	Mariners	353	295	.545	648	21,707	2,890	5,109	973	53	830	2,767	2,259	405	6,071	502	122	24,576	8,678	1,856	51	154	73	423	.235	.317	.400	.717
9	Orioles	350	298	.540	648	21,907	2,944	5,344	1,097	105	780	2,821	1,961	267	5,576	428	117	24,354	8,991	1,982	43	176	53	382	.244	.311	.410	.722
10	Blue Jays	349	299	.539	648	22,034	2,990	5,654	1,173	70	735	2,872	2,080	267	4,877	315	110	24,597	9,172	1,978	61	155	70	524	.257	.326	.416	.742
11	Guardians	348	299	.538	647	21,691	2,711	5,251	1,055	96	604	2,575	1,881	283	4,804	547	143	24,124	8,310	1,755	80	189	136	412	.242	.308	.383	.692
12	Mets	348	300	.537	648	21,819	3,023	5,414	1,034	82	817	2,908	2,112	398	5,255	433	77	24,564	9,063	1,933	64	171	75	451	.248	.323	.415	.739
13	Rays	342	306	.528	648	21,782	2,844	5,341	1,065	80	698	2,705	1,975	276	5,697	627	179	24,216	8,660	1,843	39	144	45	398	.245	.314	.398	.712
14	Cubs	332	316	.512	648	21,865	3,005	5,381	1,054	119	748	2,873	2,177	277	5,478	555	136	24,564	8,917	1,921	61	184	62	386	.246	.320	.408	.728
15	Diamondbacks	327	321	.505	648	21,789	3,125	5,420	1,084	143	764	2,977	2,185	283	5,169	509	124	24,625	9,082	1,991	138	230	63	439	.249	.322	.417	.739
16	Red Sox	326	322	.503	648	22,240	3,044	5,682	1,326	85	717	2,910	1,975	279	5,734	447	128	24,703	9,329	2,128	43	166	92	458	.255	.322	.419	.741
17	Cardinals	325	323	.502	648	21,946	2,852	5,456	1,075	63	719	2,728	2,063	294	5,191	377	110	24,532	8,814	1,857	60	169	55	440	.249	.319	.402	.721
18	Giants	321	327	.495	648	21,639	2,788	5,096	1,016	89	707	2,667	2,163	294	5,786	257	78	24,342	8,411	1,812	55	191	62	443	.236	.311	.389	.700
19	Tigers	317	331	.489	648	21,754	2,658	5,151	968	139	635	2,545	1,875	224	5,801	269	87	24,051	8,302	1,742	32	166	42	395	.237	.302	.382	.683
20	Twins	317	331	.489	648	21,887	2,894	5,339	1,091	85	785	2,758	2,080	343	5,685	303	92	24,510	8,955	1,961	41	159	49	472	.244	.317	.409	.726
21	Rangers	317	331	.489	648	21,988	2,955	5,355	1,015	68	782	2,825	2,031	218	5,473	438	118	24,429	8,852	1,865	37	155	68	373	.244	.312	.403	.714
22	Reds	304	344	.469	648	21,652	2,846	5,198	1,010	107	695	2,705	2,031	322	5,804	560	156	24,215	8,507	1,812	61	149	36	420	.240	.313	.393	.706
23	Marlins	294	354	.454	648	21,957	2,598	5,399	1,021	95	614	2,475	1,751	229	5,373	471	137	24,165	8,452	1,730	69	159	58	492	.246	.306	.385	.691
24	Royals	289	359	.446	648	21,717	2,702	5,337	1,061	138	630	2,613	1,735	240	4,940	512	154	23,975	8,564	1,829	86	197	60	388	.246	.306	.394	.700
25	Pirates	285	363	.440	648	21,589	2,531	5,006	989	98	594	2,421	2,047	226	5,889	427	128	24,089	7,973	1,681	73	154	56	411	.232	.303	.369	.672