Between the 1920 and 1929 seasons, Dazzy Vance struck out the most hitters, with 1,464 strikeouts.

Interpreted as:

most pitching ks by a player in the 1920s

	NAME	SO	G	W	L	W%	GS	ERA	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Dazzy Vance D. Vance	1,464	266	147	90	.620	244	3.10	172	22	4	2053.2	1,891	708	820	83	583	61	18	8,506	24	6.42	2.55	2.51	0.36	17.2	6.9	1.20	.286	3.59	77	3.05	76	8.29	219.9
2	Burleigh Grimes B. Grimes	1,018	373	190	130	.594	336	3.52	234	20	11	2797.2	2,988	1,093	1,354	105	842	62	31	12,039	51	3.27	2.71	1.21	0.34	8.5	7.0	1.37	.288	4.36	90	3.72	94	9.61	69.1
3	Dolf Luque D. Luque	904	353	138	146	.486	302	3.09	168	21	8	2479.2	2,446	851	1,059	75	688	21	38	10,321	35	3.28	2.50	1.31	0.27	8.8	6.7	1.26	.275	3.84	82	3.52	93	8.88	74.3
4	Walter Johnson W. Johnson	895	258	120	88	.577	227	3.33	143	24	12	1823.2	1,768	675	799	66	545	63	28	7,669	25	4.42	2.69	1.64	0.33	11.7	7.1	1.27	.279	3.94	84	3.49	89	8.73	88
5	Lefty Grove L. Grove	837	222	87	52	.626	147	3.09	82	8	23	1254.1	1,191	430	530	41	456	17	50	5,318	31	6.01	3.27	1.84	0.29	15.7	8.6	1.31	.290	3.80	73	3.24	77	8.55	133.2
6	Howard Ehmke H. Ehmke	824	333	136	137	.498	275	3.81	162	14	13	2265.0	2,319	959	1,151	89	805	118	43	9,783	17	3.27	3.20	1.02	0.35	8.4	8.2	1.38	.281	4.57	93	3.99	98	9.21	23.1
7	George Uhle G. Uhle	808	356	152	124	.551	285	3.97	182	16	16	2309.2	2,570	1,019	1,214	64	719	90	51	10,125	43	3.15	2.80	1.12	0.25	8.0	7.1	1.42	.297	4.73	95	3.72	90	10.01	112.1
8	Red Faber R. Faber	804	316	149	116	.562	297	3.34	181	17	4	2364.0	2,429	878	1,045	73	664	47	14	9,958	28	3.06	2.53	1.21	0.28	8.1	6.7	1.31	.281	3.98	83	3.62	90	9.25	101.7
9	Bob Shawkey B. Shawkey	788	270	106	83	.561	183	3.45	99	15	14	1612.2	1,590	618	721	87	565	23	58	6,786	28	4.40	3.15	1.39	0.49	11.6	8.3	1.34	.282	4.02	85	3.80	95	8.87	35.9
10	Urban Shocker U. Shocker	753	330	156	93	.627	261	3.34	168	22	22	2148.2	2,256	797	946	117	484	26	53	9,020	10	3.15	2.03	1.56	0.49	8.3	5.4	1.28	.280	3.96	80	3.71	90	9.45	102.2
11	Waite Hoyt W. Hoyt	748	379	161	102	.612	280	3.51	160	17	30	2346.0	2,464	914	1,080	88	669	33	80	9,964	25	2.87	2.57	1.12	0.34	7.5	6.7	1.34	.282	4.14	87	3.75	94	9.45	57.6
12	Jesse Haines J. Haines	742	346	153	119	.563	293	3.61	169	20	5	2328.1	2,490	935	1,132	122	644	47	32	9,897	33	2.87	2.49	1.15	0.47	7.5	6.5	1.35	.284	4.38	92	3.92	99	9.62	3.6
13	Herb Pennock H. Pennock	731	352	163	112	.593	286	3.44	181	21	23	2313.0	2,485	883	1,038	87	556	21	48	9,743	28	2.84	2.16	1.31	0.34	7.5	5.7	1.31	.287	4.04	86	3.60	91	9.67	88.4
14	Sad Sam Jones S. Sam Jones	718	363	137	118	.537	278	3.83	150	21	23	2230.0	2,345	948	1,137	85	791	36	59	9,559	37	2.90	3.19	0.91	0.34	7.5	8.3	1.41	.285	4.59	95	3.95	99	9.46	9.4
15	Jimmy Ring J. Ring	713	312	96	128	.429	251	4.39	126	3	6	1944.0	2,181	948	1,172	96	819	23	34	8,652	81	3.30	3.79	0.87	0.44	8.2	9.5	1.54	.298	5.43	106	4.18	100	10.10	17.6
16	Eppa Rixey E. Rixey	686	386	166	142	.539	330	3.24	185	20	10	2678.1	2,827	964	1,169	59	567	37	47	11,150	38	2.31	1.91	1.21	0.20	6.2	5.1	1.27	.282	3.93	85	3.44	89	9.50	117.2
17	Bill Sherdel B. Sherdel	657	378	139	108	.563	209	3.70	128	10	24	2061.1	2,317	848	999	116	490	45	118	8,853	18	2.87	2.14	1.34	0.51	7.4	5.5	1.36	.292	4.36	93	3.86	97	10.12	28.7
18	Grover Alexander G. Alexander	653	325	165	105	.611	290	3.04	194	20	16	2415.1	2,528	816	982	111	349	15	29	9,893	18	2.43	1.30	1.87	0.41	6.6	3.5	1.19	.276	3.66	77	3.48	88	9.42	127
19	Slim Harriss S. Harriss	644	349	95	135	.413	229	4.25	89	7	17	1750.1	1,963	827	1,006	73	630	41	78	7,661	19	3.31	3.24	1.02	0.38	8.4	8.2	1.48	.301	5.17	102	3.94	95	10.09	41.9
20	Bullet Joe Bush B. Joe Bush	631	270	118	94	.557	215	3.97	129	13	11	1725.2	1,777	761	863	79	687	39	44	7,450	41	3.29	3.58	0.92	0.41	8.5	9.2	1.43	.282	4.50	98	4.10	102	9.27	-18.7
21	Jack Scott J. Scott	588	329	96	101	.487	180	3.92	105	11	18	1666.1	1,819	726	839	91	446	39	113	7,134	22	3.18	2.41	1.32	0.49	8.2	6.3	1.36	.289	4.53	104	3.85	100	9.82	-4.3
22	Dutch Ruether D. Ruether	585	257	115	86	.572	233	3.75	131	14	8	1800.0	1,959	750	882	53	627	53	20	7,825	20	2.93	3.14	0.93	0.27	7.5	8.0	1.44	.293	4.41	98	3.84	100	9.80	-5.9
23	Wilbur Cooper W. Cooper	577	248	120	95	.558	221	3.36	151	16	3	1793.0	1,946	669	805	74	395	51	18	7,562	14	2.90	1.98	1.46	0.37	7.6	5.2	1.31	.290	4.04	87	3.62	93	9.77	54.9
24	Jack Quinn J. Quinn	575	368	131	111	.541	251	3.50	124	19	22	2042.0	2,317	795	983	65	432	47	68	8,739	24	2.53	1.90	1.33	0.29	6.6	4.9	1.35	.296	4.33	85	3.54	86	10.21	126.3
25	Lee Meadows L. Meadows	574	287	128	103	.554	255	3.66	146	15	2	1946.1	2,130	792	973	65	524	48	19	8,317	30	2.65	2.42	1.10	0.30	6.9	6.3	1.36	.291	4.50	90	3.71	90	9.85	92.9