Walter Johnson has won the most career games for the Washington Senators, with 417 wins.

Interpreted as:

most pitching regular-season wins by a player in twins history

	NAME	W	L	W%	G	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Walter Johnson W. Johnson	417	279	.599	802	666	2.17	3,509	531	110	34	5914.1	4,913	1,424	1,902	97	1,363	205	127		23,405	154	5.34	2.07	2.57	0.15	15.0	5.8	1.06	.264	2.89	68	2.42	76	7.48	472.8
2	Jim Kaat J. Kaat	190	159	.544	484	433	3.34	1,851	133	23	5	3014.1	2,982	1,118	1,343	279	729	96	20	61	12,642	106	5.53	2.18	2.54	0.83	14.6	5.8	1.23	.279	4.01	91	3.33	88	8.90	148.3
3	Bert Blyleven B. Blyleven	149	138	.519	348	345	3.28	2,035	141	29	0	2566.2	2,369	934	1,044	243	674	80	2	37	10,542	56	7.14	2.36	3.02	0.85	19.3	6.4	1.19	.283	3.66	84	3.14	81	8.31	202.7
4	Brad Radke B. Radke	148	139	.516	378	377	4.22	1,467	37	10	0	2451.0	2,643	1,150	1,233	326	445	62	0	12	10,244	28	5.39	1.63	3.30	1.20	14.3	4.3	1.26	.292	4.53	90	4.24	94	9.71	75.2
5	Camilo Pascual C. Pascual	145	141	.507	432	331	3.66	1,885	119	31	10	2465.0	2,283	1,002	1,127	214	909	47	60	42	10,471	69	6.88	3.32	2.07	0.78	18.0	8.7	1.29	.279	4.11	95	3.27	84	8.34	176
6	Jim Perry J. Perry	128	90	.587	376	249	3.15	1,025	61	17	5	1883.1	1,711	659	736	166	541	50	35	56	7,791	37	4.90	2.59	1.89	0.79	13.2	6.9	1.20	.257	3.52	89	3.50	96	8.18	35.4
7	Dutch Leonard D. Leonard	118	101	.539	262	251	3.27	657	130	23	2	1899.1	1,951	690	852	84	403	30	6		7,956	55	3.11	1.91	1.63	0.40	8.3	5.1	1.24	.275	4.04	86	3.25	86	9.24	109.1
8	Firpo Marberry F. Marberry	117	71	.622	470	133	3.59	667	64	5	94	1654.0	1,620	659	769	69	568	37	251		6,994	10	3.63	3.09	1.17	0.38	9.5	8.1	1.32	.274	4.18	85	3.93	94	8.81	41.7
9	Frank Viola F. Viola	112	93	.546	260	259	3.86	1,214	54	10	0	1772.2	1,775	760	842	213	521	29	0	17	7,450	45	6.16	2.65	2.33	1.08	16.3	7.0	1.30	.285	4.27	91	3.88	95	9.01	39.2
10	Casey Patten C. Patten	106	127	.455	269	237	3.34	757	206	17	4	2059.1	2,146	765	1,074	40	556	74	28		8,606	28	3.31	2.43	1.36	0.17	8.8	6.5	1.31	.293	4.69	115	2.98	105	9.38	-26.9
11	Alvin Crowder A. Crowder	98	69	.587	236	161	3.98	450	85	6	12	1331.0	1,373	589	667	66	439	9	46		5,714	12	3.04	2.97	1.03	0.45	7.9	7.7	1.36	.275	4.51	93	4.04	96	9.28	21.5
12	Dave Goltz D. Goltz	96	79	.549	247	215	3.48	887	80	11	3	1638.0	1,654	634	729	119	493	24	15	19	6,887	54	4.87	2.71	1.80	0.65	12.9	7.2	1.31	.286	4.01	90	3.43	90	9.09	73.9
13	Tom Zachary T. Zachary	96	103	.482	273	210	3.78	327	92	10	8	1589.0	1,822	668	803	54	460	26	44		6,802	23	1.85	2.61	0.71	0.31	4.8	6.8	1.44	.298	4.55	97	3.91	101	10.32	-12.1
14	Johan Santana J. Santana	93	44	.679	251	175	3.22	1,381	6	4	1	1308.2	1,068	468	500	144	364	27	23	2	5,281	55	9.50	2.50	3.79	0.99	26.2	6.9	1.09	.275	3.44	71	3.30	76	7.34	154.5
15	Sid Hudson S. Hudson	88	130	.404	296	239	4.38	597	112	11	6	1819.1	1,992	886	1,040	109	720	35	40		8,030	27	2.95	3.56	0.83	0.54	7.4	9.0	1.49	.287	5.14	110	3.94	101	9.85	-6.2
16	Jim Shaw J. Shaw	84	98	.462	287	194	3.07	767	96	17	16	1600.1	1,446	546	677	28	688	24	66		6,574	58	4.31	3.87	1.11	0.16	11.7	10.5	1.33	.280	3.81	102	3.04	101	8.13	-12.9
17	Tom Hughes T. Hughes	84	124	.404	285	205	3.02	884	139	17	15	1776.0	1,726	595	857	38	567	67	67		7,329	51	4.48	2.87	1.56	0.19	12.1	7.7	1.29	.292	4.34	111	2.79	105	8.75	-34.3
18	Pedro Ramos P. Ramos	78	112	.411	290	199	4.19	740	58	10	12	1544.1	1,579	719	808	210	491	46	56	34	6,625	23	4.31	2.86	1.51	1.22	11.2	7.4	1.34	.266	4.71	106	4.34	109	9.20	-58.7
19	Kevin Tapani K. Tapani	75	63	.543	181	180	4.06	724	19	6	0	1171.1	1,228	528	565	109	255	23	0	8	4,897	16	5.56	1.96	2.84	0.84	14.8	5.2	1.27	.296	4.34	93	3.60	86	9.44	77.7
20	Mickey Haefner M. Haefner	73	77	.487	215	156	3.29	464	84	12	12	1291.2	1,224	472	562	53	479	32	37		5,528	15	3.23	3.34	0.97	0.37	8.4	8.7	1.32	.260	3.92	94	3.50	100	8.53	-2.3
21	Early Wynn E. Wynn	72	87	.453	191	168	3.94	386	92	9	2	1266.2	1,359	554	655	64	460	15	21		5,514	18	2.74	3.27	0.84	0.45	7.0	8.3	1.44	.282	4.65	109	3.68	103	9.66	-21.4
22	Bob Groom B. Groom	72	89	.447	195	169	3.04	699	104	12	3	1353.1	1,287	457	630	30	424	40	19		5,503	42	4.65	2.82	1.65	0.20	12.7	7.7	1.26	.292	4.19	106	2.84	101	8.56	-0.4
23	Monte Weaver M. Weaver	70	50	.583	192	134	4.32	291	56	2	3	1031.2	1,111	495	576	62	422	4	36		4,533	15	2.54	3.68	0.69	0.54	6.4	9.3	1.49	.279	5.02	98	4.48	104	9.69	-25.6
24	Bump Hadley B. Hadley	68	71	.489	233	162	3.98	601	65	6	10	1299.0	1,270	575	668	44	572	33	45		5,636	21	4.16	3.96	1.05	0.30	10.7	10.1	1.42	.280	4.63	94	4.05	96	8.80	23.5
25	George Mogridge G. Mogridge	68	55	.553	145	136	3.38	284	72	12	1	1016.2	1,104	382	453	38	273	32	7		4,341	9	2.51	2.42	1.04	0.34	6.5	6.3	1.35	.287	4.01	85	3.86	98	9.77	6.7