Since 2004, Justin Verlander has won the most games, with 262 wins.

Interpreted as:

most pitching regular-season wins by a player since 2004

	NAME	W	L	W%	G	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Justin Verlander J. Verlander	262	149	.637	534	534	3.31	3,451	26	9	0	3457.2	2,931	1,273	1,377	361	967	116	0	27	14,123	97	8.98	2.52	3.57	0.94	24.4	6.8	1.13	.279	3.58	78	3.43	81	7.63	306.1
2	Zack Greinke Z. Greinke	225	156	.591	586	541	3.49	2,979	17	5	1	3389.1	3,207	1,315	1,410	367	762	79	8	25	13,877	101	7.91	2.02	3.91	0.97	21.5	5.5	1.17	.293	3.74	83	3.51	85	8.52	235
3	Max Scherzer M. Scherzer	215	112	.657	467	458	3.16	3,408	12	5	0	2881.0	2,349	1,012	1,085	337	756	112	2	20	11,640	78	10.65	2.36	4.51	1.05	29.3	6.5	1.08	.286	3.39	76	3.18	77	7.34	307.8
4	Clayton Kershaw C. Kershaw	212	94	.693	432	429	2.50	2,968	25	15	0	2742.2	2,091	762	835	227	678	44	1	28	10,816	103	9.74	2.22	4.38	0.74	27.4	6.3	1.01	.270	2.74	64	2.82	70	6.86	366.8
5	CC Sabathia	208	136	.605	465	464	3.66	2,632	34	11	0	2989.1	2,867	1,216	1,336	327	850	109	0	38	12,503	57	7.92	2.56	3.10	0.98	21.1	6.8	1.24	.296	4.02	85	3.73	86	8.63	198.3
6	Jon Lester J. Lester	200	117	.631	452	451	3.66	2,488	15	4	0	2740.0	2,610	1,114	1,215	294	892	90	0	13	11,487	63	8.17	2.93	2.79	0.97	21.7	7.8	1.28	.300	3.99	86	3.77	92	8.57	101.7
7	Adam Wainwright A. Wainwright	200	128	.610	478	411	3.53	2,202	28	11	3	2668.1	2,577	1,047	1,117	233	736	81	13	40	11,116	51	7.43	2.48	2.99	0.79	19.8	6.6	1.24	.298	3.77	88	3.53	87	8.69	152.8
8	Felix Hernandez F. Hernandez	169	136	.554	419	418	3.42	2,524	25	11	0	2729.2	2,487	1,037	1,157	264	805	105	0	16	11,284	156	8.32	2.65	3.14	0.87	22.4	7.1	1.21	.293	3.81	84	3.52	85	8.20	181.5
9	John Lackey J. Lackey	169	127	.571	397	395	3.87	2,074	15	6	0	2528.0	2,526	1,088	1,178	278	716	119	0	28	10,680	107	7.38	2.55	2.90	0.99	19.4	6.7	1.28	.300	4.19	91	3.88	94	8.99	79.3
10	Cole Hamels C. Hamels	163	122	.572	423	422	3.43	2,560	17	7	0	2698.0	2,424	1,027	1,103	310	767	100	0	43	11,115	57	8.54	2.56	3.34	1.03	23.0	6.9	1.18	.287	3.68	82	3.68	88	8.09	151.3
11	Mark Buehrle M. Buehrle	161	125	.563	389	389	3.84	1,454	22	6	0	2541.1	2,743	1,085	1,200	285	545	60	0	37	10,633	19	5.15	1.93	2.67	1.01	13.7	5.1	1.29	.297	4.25	88	4.12	95	9.71	65.8
12	David Price D. Price	157	82	.657	400	322	3.32	2,076	17	3	3	2143.2	1,930	790	865	221	562	63	19	16	8,807	40	8.72	2.36	3.69	0.93	23.6	6.4	1.16	.290	3.63	81	3.38	83	8.10	165.9
13	Gerrit Cole G. Cole	153	80	.657	317	317	3.18	2,251	8	5	0	1954.0	1,627	690	740	217	500	61	0	8	7,861	58	10.37	2.30	4.50	1.00	28.6	6.4	1.09	.292	3.41	79	3.16	77	7.49	213.5
14	Ervin Santana E. Santana	151	129	.539	425	386	4.11	1,978	21	11	0	2486.2	2,391	1,135	1,221	331	776	104	20	35	10,482	104	7.16	2.81	2.55	1.20	18.9	7.4	1.27	.282	4.42	99	4.31	104	8.65	-44.1
15	Rick Porcello R. Porcello	150	125	.545	355	351	4.40	1,561	10	3	0	2096.1	2,270	1,025	1,122	260	489	84	2	17	8,912	70	6.70	2.10	3.19	1.12	17.5	5.5	1.32	.308	4.82	102	4.06	97	9.75	26.3
16	Jered Weaver J. Weaver	150	98	.605	331	331	3.63	1,621	14	8	0	2067.1	1,912	833	879	262	551	55	0	17	8,531	37	7.06	2.40	2.94	1.14	19.0	6.5	1.19	.273	3.83	89	4.06	99	8.32	5.6
17	Dan Haren D. Haren	150	124	.547	377	366	3.71	1,970	16	6	1	2347.0	2,273	968	1,061	296	478	62	4	39	9,702	95	7.55	1.83	4.12	1.14	20.3	4.9	1.17	.287	4.07	91	3.75	92	8.72	95.5
18	Bartolo Colon B. Colon	147	126	.538	352	341	4.29	1,415	10	6	0	2073.0	2,271	989	1,081	291	423	38	2	22	8,783	12	6.14	1.84	3.35	1.26	16.1	4.8	1.30	.299	4.69	103	4.22	101	9.86	-17.4
19	James Shields J. Shields	145	139	.511	407	405	4.01	2,234	23	9	0	2616.0	2,581	1,167	1,267	361	746	97	1	22	10,993	107	7.69	2.57	2.99	1.24	20.3	6.8	1.27	.294	4.36	98	4.16	101	8.88	-13.5
20	Johnny Cueto J. Cueto	144	113	.560	370	365	3.52	1,857	18	8	0	2256.1	2,094	883	955	253	637	120	1	22	9,373	36	7.41	2.54	2.92	1.01	19.8	6.8	1.21	.283	3.81	86	3.93	96	8.35	31.8
21	Roy Halladay R. Halladay	144	74	.661	272	271	3.18	1,510	53	15	0	1907.2	1,801	675	723	162	350	58	0	20	7,721	30	7.12	1.65	4.31	0.76	19.6	4.5	1.13	.291	3.41	75	3.26	76	8.50	214.5
22	Lance Lynn L. Lynn	142	99	.589	364	340	3.74	2,015	4	2	1	2006.1	1,856	834	916	231	704	89	4	21	8,520	61	9.04	3.16	2.86	1.04	23.7	8.3	1.28	.296	4.11	91	3.82	93	8.33	67.8
23	Tim Hudson T. Hudson	142	100	.587	326	323	3.61	1,284	13	7	0	2074.2	2,017	832	892	162	579	89	0	54	8,648	49	5.57	2.51	2.22	0.70	14.8	6.7	1.25	.284	3.87	89	3.84	95	8.75	49
24	Cliff Lee C. Lee	140	87	.617	317	313	3.52	1,774	29	12	0	2094.0	2,069	820	893	216	436	48	1	10	8,663	38	7.62	1.87	4.07	0.93	20.5	5.0	1.20	.299	3.84	84	3.42	82	8.89	167.8
25	Chris Sale C. Sale	139	86	.618	380	300	3.06	2,470	16	3	12	2000.1	1,636	680	732	207	466	123	25	15	8,064	47	11.11	2.10	5.30	0.93	30.6	5.8	1.05	.298	3.29	72	2.89	69	7.36	288