Ed Siever has given up the most runs in a game with exactly 0 earned runs, with 14 runs against the Cleveland Naps on July 5, 1904.
| NAME | DATE | TM | OPP | DEC | R | ER | GS | CG | GF | SHO | SV | IP | H | TBF | HR | BB | IBB | HBP | SO | WP | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 Ed Siever | 7/5/1904 |  SLA | @ |  CLE | L | 14 | 0 | 1 | 1 | 0 | 0 | 0 | 8.0 | 19 | 43 | 1 | 0 | 0 | 1 | 0 | |
 Pete Appleton | 8/10/1930 |  CLE | @ |  WSH | 11 | 0 | 0 | 0 | 1 | 0 | 0 | 1.0 | 7 | 15 | 0 | 4 | 0 | 0 | 2 | ||
 Andy Hawkins | 6/5/1989 |  NYY | vs |  BAL | L | 10 | 0 | 1 | 0 | 0 | 0 | 0 | 2.1 | 5 | 18 | 0 | 3 | 1 | 0 | 1 | 0 |
 Chris Reitsma | 7/3/2002 |  CIN | vs |  HOU | L | 9 | 0 | 1 | 0 | 0 | 0 | 0 | 4.0 | 7 | 21 | 2 | 0 | 0 | 0 | 5 | 0 |
 Bobby Jones | 5/2/1994 |  NYM | vs |  SFG | L | 9 | 0 | 1 | 0 | 0 | 0 | 0 | 2.2 | 7 | 19 | 1 | 2 | 1 | 0 | 0 | 1 |
 Luis Tiant | 5/8/1976 |  BOS | vs |  TEX | L | 9 | 0 | 1 | 0 | 0 | 0 | 0 | 1.2 | 6 | 15 | 1 | 3 | 0 | 0 | 1 | 0 |
| Dean Stone | 7/14/1957 |  BOS | @ | CLE | 9 | 0 | 0 | 0 | 1 | 0 | 0 | 2.0 | 4 | 16 | 0 | 5 | 0 | 0 | 2 | 0 | |
| Red Ruffing | 8/3/1929 |  BSA | vs |  CWS | L | 9 | 0 | 1 | 0 | 0 | 0 | 0 | 2.2 | 10 | 20 | 1 | 1 | 0 | 6 | 0 | |
 Cy Falkenberg | 5/7/1917 |  PHA | vs | NYY | L | 9 | 0 | 1 | 1 | 0 | 0 | 0 | 9.0 | 7 | 41 | 1 | 5 | 0 | 4 | 0 | |
| Charley Hall | 5/10/1913 | BSA | @ |  CLE | L | 9 | 0 | 1 | 0 | 0 | 0 | 0 | 6.0 | 9 | 42 | 0 | 4 | 2 | 3 | 0 | |
 Patsy Flaherty | 5/6/1903 |  CWS | vs |  DET | W | 9 | 0 | 1 | 1 | 0 | 0 | 0 | 9.0 | 6 | 46 | 0 | 3 | 1 | 1 | 2 | |
 Ed Murphy | 5/1/1902 |  SLN | @ |  PIT | 9 | 0 | 0 | 0 | 1 | 0 | 0 | 6.0 | 10 | 0 | 5 | 0 | 1 | 2 | |||
 Tom Hughes | 10/6/1901 |  CHO | vs | PIT | L | 9 | 0 | 1 | 1 | 0 | 0 | 0 | 9.0 | 4 | 42 | 0 | 4 | 2 | 5 | 0 | |
 Mark Buehrle | 10/4/2015 |  TOR | @ |  TBR | L | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 0.2 | 5 | 10 | 1 | 1 | 0 | 0 | 0 | 0 |
 Scott Olsen | 9/21/2007 |  FLA | vs | NYM | L | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 5.0 | 7 | 28 | 0 | 3 | 0 | 0 | 1 | 0 |
 Horacio Ramirez | 5/2/2004 |  ATL | @ |  COL | L | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 3.1 | 5 | 22 | 0 | 3 | 0 | 0 | 1 | 0 |
| Todd Ritchie | 6/1/2002 | CWS | @ | CLE | L | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 5.0 | 4 | 23 | 1 | 2 | 0 | 0 | 3 | 0 |
 Eric Knott | 10/7/2001 |  ARI | @ |  MIL | L | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 3.2 | 7 | 21 | 0 | 0 | 0 | 2 | 4 | 0 |
 Bill Wegman | 8/3/1991 |  MIL | vs |  TEX | L | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 0.2 | 5 | 10 | 0 | 1 | 0 | 0 | 0 | 0 |
| Bill Dietrich | 8/24/1943 | CWS | vs | PHA | L | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 3.0 | 8 | 19 | 0 | 0 | 0 | 2 | 0 | |
| Tex Shirley | 7/29/1942 | PHA | @ | DET | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 1.0 | 5 | 12 | 0 | 1 | 1 | 0 | 0 | ||
 Bobo Newsom | 8/22/1940 | DET | @ |  BSA | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 1.2 | 6 | 15 | 2 | 3 | 0 | 2 | 0 | ||
| Ed Heusser | 7/15/1940 | PHA | vs | DET | L | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 3.1 | 8 | 24 | 1 | 4 | 0 | 2 | 0 | |
| Lynn Nelson | 7/8/1938 | PHA | @ | WSH | L | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 6.0 | 8 | 30 | 0 | 1 | 0 | 1 | 0 | |
 Van Mungo | 5/6/1938 |  BKN | @ | CIN | L | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 4.0 | 6 | 26 | 0 | 5 | 0 | 3 | 0 | |
| Ed Wells | 5/18/1931 | NYY | @ | DET | W | 8 | 0 | 1 | 1 | 0 | 0 | 0 | 9.0 | 12 | 41 | 2 | 1 | | 1 | 3 | 0 |
| Tommy Thomas | 5/3/1931 | CWS | vs | SLA | L | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 5.1 | 10 | 30 | 0 | 0 | | 0 | 5 | 0 |
| Tom Zachary | 4/15/1926 | SLA | @ | CWS | L | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 0.2 | 4 | 10 | 0 | 2 | | 0 | 0 | 0 |
| Pete Donohue | 9/10/1923 | CIN | vs | PIT | L | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 3.1 | 5 | 21 | 0 | 5 | | 0 | 2 | 0 |
| George Smith | 8/1/1923 | BKN | @ |  SLN | | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 5.0 | 7 | 27 | 0 | 2 | | 0 | 2 | 0 |
| Bob Hasty | 7/29/1921 | PHA | vs | DET | L | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 2.0 | 6 | 15 | 1 | 1 | | 0 | 0 | 0 |
 Jesse Barnes | 6/21/1921 |  NYG | vs |  BSN | L | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 4.0 | 7 | 23 | 0 | 2 | | 0 | 0 | 0 |
| Allen Sothoron | 5/20/1920 | SLA | @ | NYY | L | 8 | 0 | 1 | 1 | 0 | 0 | 0 | 8.0 | 10 | 41 | 0 | 3 | | 0 | 4 | 1 |
| Tim McCabe | 7/15/1916 | SLA | @ | BSA | | 8 | 0 | 0 | 0 | 1 | 0 | 0 | 4.1 | 8 | 25 | 0 | 1 | | 1 | 0 | 0 |
 Claude Hendrix | 8/21/1915 |  CHF | @ | BUF | L | 8 | 0 | 1 | 0 | 0 | 0 | 0 | 4.1 | 7 | | 0 | 2 | | 0 | 2 | 0 |
| Jack Taylor | 7/11/1902 | CHO | vs |  PHN | L | 8 | 0 | 1 | 1 | 0 | 0 | 0 | 9.0 | 13 | 42 | 0 | 2 | | 0 | 2 | 2 |
 Anthony DeSclafani | 6/26/2022 | SFG | vs | CIN | L | 7 | 0 | 1 | 0 | 0 | 0 | 0 | 2.2 | 6 | 16 | 0 | 1 | 0 | 0 | 1 | 0 |
 Josh Fleming | 4/26/2022 | TBR | vs |  SEA | L | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 2.0 | 4 | 14 | 0 | 1 | 0 | 1 | 2 | 0 |
 Mark Leiter Jr. | 8/16/2018 | PHI | vs | NYM | | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 1.0 | 4 | 12 | 1 | 3 | 1 | 0 | 0 | 0 |
 Jeff Hoffman | 9/8/2016 | COL | @ |  SDP | L | 7 | 0 | 1 | 0 | 0 | 0 | 0 | 2.2 | 6 | 17 | 1 | 2 | 0 | 0 | 3 | 2 |
| A.J. Schugel | 9/4/2015 |  ARI | @ |  CHC | | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0.2 | 5 | 9 | 1 | 2 | 0 | 0 | 0 | 0 |
| Mike Leake | 8/3/2010 | CIN | @ |  PIT | L | 7 | 0 | 1 | 0 | 0 | 0 | 0 | 5.0 | 6 | 23 | 0 | 1 | 0 | 1 | 2 | 0 |
| Roy Halladay | 9/28/2000 |  TOR | @ |  BAL | | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0.2 | 5 | 9 | 0 | 1 | 0 | 0 | 0 | 0 |
| Tim Wakefield | 9/26/1999 | BOS | vs | BAL | L | 7 | 0 | 1 | 0 | 0 | 0 | 0 | 4.2 | 4 | 23 | 1 | 1 | 1 | 1 | 3 | 0 |
| Paul Spoljaric | 8/31/1999 | TOR | vs |  MIN | | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 1.2 | 6 | 14 | 1 | 2 | 0 | 0 | 2 | 0 |
| Russ Ortiz | 7/26/1999 | SFG | vs | STL | | 7 | 0 | 1 | 0 | 0 | 0 | 0 | 2.0 | 4 | 17 | 1 | 6 | 0 | 0 | 1 | 0 |
| Eddie Gaillard | 5/7/1999 |  TBD | @ | CLE | | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0.2 | 5 | 10 | 1 | 2 | 0 | 0 | 1 | 0 |
 Carlos Perez | 9/24/1997 |  MON | vs | FLA | L | 7 | 0 | 1 | 0 | 0 | 0 | 0 | 0.1 | 5 | 10 | 1 | 2 | 0 | 0 | 0 | 0 |
 Mark Small | 4/7/1996 |  HOU | vs |  SDP | | 7 | 0 | 0 | 0 | 1 | 0 | 0 | 3.0 | 5 | 19 | 1 | 2 | 0 | 0 | 4 | 0 |
| Rod Nichols | 8/12/1995 | ATL | vs | COL | | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0.2 | 5 | 9 | 2 | 1 | 0 | 0 | 1 | 0 |
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