Since 2000, 6 players are tied for the most RBIs in a game, with 10 RBIs. The first three are Shohei Ohtani on September 19, Mark Reynolds on July 7, 2018 and Scooter Gennett on June 6, 2017.

Interpreted as:

most rbi by a player in a single regular-season game since 2000

	NAME	RBI	DATE	TM		OPP	AB	R	H	2B	3B	HR	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP
1	Shohei Ohtani S. Ohtani	10	9/19/2024	LAD	@	MIA	6	4	6	2	0	3	0	0	0	2	0	6	17	5	0	0	0	0
2	Mark Reynolds M. Reynolds	10	7/7/2018	WSH	vs	MIA	5	3	5	1	0	2	0	0	0	0	0	5	12	3	0	0	0	0
3	Scooter Gennett S. Gennett	10	6/6/2017	CIN	vs	STL	5	4	5	0	0	4	0	0	0	0	0	5	17	4	0	0	0	0
4	Anthony Rendon A. Rendon	10	4/30/2017	WSH	vs	NYM	6	5	6	1	0	3	0	0	0	0	0	6	16	4	0	0	0	0
5	Garret Anderson G. Anderson	10	8/21/2007	LAA	vs	NYY	6	3	4	2	0	2	0	0	0	0	0	6	12	4	0	0	0	0
6	Alex Rodriguez A. Rodriguez	10	4/26/2005	NYY	vs	LAA	5	3	4	0	0	3	0	0	0	0	0	5	13	3	0	0	0	0
7	Brandon Nimmo B. Nimmo	9	4/28/2025	NYM	@	WSH	6	4	4	1	0	2	0	0	0	0	0	6	11	3	0	0	0	0
8	Ryan Mountcastle R. Mountcastle	9	4/11/2023	BAL	vs	OAK	4	2	3	0	0	2	0	0	0	0	0	5	9	2	0	1	0	0
9	Adam Duvall A. Duvall	9	9/9/2020	ATL	vs	MIA	4	5	3	0	0	3	2	0	1	0	0	6	12	3	0	0	0	0
10	Mike Moustakas M. Moustakas	9	9/12/2015	KCR	@	BAL	5	3	3	0	0	2	0	0	1	0	0	5	9	2	0	0	0	0
11	Edwin Encarnacion E. Encarnacion	9	8/29/2015	TOR	vs	DET	5	4	3	0	0	3	0	0	0	0	0	5	12	3	0	0	0	0
12	Lonnie Chisenhall L. Chisenhall	9	6/9/2014	CLE	@	TEX	5	3	5	1	0	3	0	0	0	0	0	5	15	4	0	0	0	0
13	Carlos Delgado C. Delgado	9	6/27/2008	NYM	@	NYY	5	2	3	1	0	2	0	0	1	0	0	5	10	3	0	0	0	0
14	James Loney J. Loney	9	9/28/2006	LAD	@	COL	5	2	4	1	0	2	0	0	1	0	0	5	11	3	0	0	0	0
15	Vladimir Guerrero V. Guerrero	9	6/2/2004	ANA	vs	BOS	4	2	4	1	0	2	0	0	0	0	0	5	11	3	0	1	0	0
16	Bill Mueller B. Mueller	9	7/29/2003	BOS	@	TEX	5	3	3	0	0	3	0	0	0	0	0	5	12	3	0	0	0	0
17	Sammy Sosa S. Sosa	9	8/10/2002	CHC	@	COL	4	3	3	0	0	3	0	0	1	0	0	4	12	3	0	0	0	0
18	Erubiel Durazo E. Durazo	9	5/17/2002	ARI	vs	PHI	5	3	4	1	0	3	0	0	1	0	0	5	14	4	0	0	0	0
19	Christian Yelich C. Yelich	8	6/20/2025	MIL	@	MIN	6	0	4	2	0	0	0	0	0	0	0	6	6	2	0	0	0	0
20	Rafael Devers R. Devers	8	5/23/2025	BOS	vs	BAL	6	3	4	0	0	2	0	0	1	0	0	6	10	2	0	0	0	0
21	Wilmer Flores W. Flores	8	5/16/2025	SFG	vs	ATH	5	3	3	0	0	3	0	0	0	0	0	5	12	3	0	0	0	0
22	Aaron Judge A. Judge	8	3/29/2025	NYY	vs	MIL	6	4	4	1	0	3	0	0	0	0	0	6	14	4	0	0	0	0
23	Pavin Smith P. Smith	8	9/8/2024	ARI	@	HOU	4	3	3	0	0	3	1	0	1	0	0	5	12	3	0	0	0	0
24	Adolis García A. García	8	4/22/2023	TEX	vs	OAK	5	5	5	2	0	3	0	1	0	0	0	6	16	5	0	0	0	0
25	Trayce Thompson T. Thompson	8	4/1/2023	LAD	vs	ARI	4	3	3	0	0	3	0	0	1	0	0	4	12	3	0	0	0	0