Mel Ott has the most career RBIs by a player younger than 22, with 372 RBIs.

Interpreted as:

most rbis by a player before age 22

	NAME	RBI	G	AB	R	H	2B	3B	HR	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Mel Ott M. Ott	372	539	1,724	359	570	106	14	86	285	10	127	21		2,064	962	206	45				.331	.428	.558	.986
2	Al Kaline A. Kaline	275	473	1,737	269	540	74	21	59	175	7	161	23	14	1,939	833	154	8	12	16	48	.311	.374	.480	.853
3	Mickey Mantle M. Mantle	244	365	1,351	260	398	72	15	57	197	0	275	20	12	1,552	671	144	4			10	.295	.384	.497	.881
4	Ken Griffey Jr. K. Griffey Jr.	241	436	1,600	228	478	93	8	60	178	5	246	50	24	1,805	767	161	5	17	41	26	.299	.367	.479	.847
5	Ted Williams T. Williams	233	264	1,007	243	337	82	21	49	186	5	107	5		1,202	608	152	4			19	.335	.441	.604	1.045
6	Tony Conigliaro T. Conigliaro	227	399	1,483	228	405	68	14	84	137	15	306	6	8	1,657	753	166	12	10	15	26	.273	.339	.508	.846
7	Jimmie Foxx J. Foxx	223	364	1,088	241	372	61	25	49	179	4	131	15		1,302	630	135	31				.342	.437	.579	1.016
8	Juan Soto J. Soto	217	313	1,110	226	328	71	6	69	228	4	259	23	5	1,349	618	146	1	6	25	21	.295	.415	.557	.972
9	Buddy Lewis B. Lewis	214	407	1,739	287	520	74	26	25	139	7	119	29		1,907	721	125	22				.299	.353	.415	.768
10	Phil Cavarretta P. Cavarretta	212	429	1,532	201	422	71	23	24	97	8	152	22		1,656	611	118	19				.275	.322	.399	.721
11	Cesar Cedeno C. Cedeno	205	390	1,525	234	450	100	18	39	96	10	221	92	34	1,651	703	157	7	13	12	28	.295	.338	.461	.799
12	Alex Rodriguez A. Rodriguez	197	300	1,174	229	377	89	5	56	96	8	222	42	8	1,297	644	150	10	9	2	23	.321	.374	.549	.922
13	Orlando Cepeda O. Cepeda	193	290	1,173	178	371	72	8	51	60	7	174	38	20	1,253	612	131	0	13	17	29	.316	.350	.522	.871
14	Eddie Mathews E. Mathews	193	302	1,107	190	303	54	13	72	158	3	200	7	7	1,274	599	139	6			16	.274	.366	.541	.907
15	Miguel Cabrera M. Cabrera	186	259	963	147	273	52	4	48	98	8	241	5	4	1,084	477	104	4	11	8	35	.283	.351	.495	.846
16	Andruw Jones A. Jones	184	357	1,136	171	284	59	11	55	115	9	275	51	16	1,274	530	125	6	8	10	23	.250	.322	.467	.788
17	Johnny Bench J. Bench	178	328	1,182	157	325	66	4	42	85	6	201	7	12	1,292	525	112	3	16	15	26	.275	.323	.444	.767
18	Robin Yount R. Yount	175	556	2,095	238	560	94	14	17	123	4	263	51	28	2,272	733	125	34	16	7	33	.267	.307	.350	.657
19	Hank Aaron H. Aaron	175	275	1,070	164	320	64	15	40	77	6	100	5	3	1,174	534	119	13	8	5	34	.299	.347	.499	.846
20	Adrian Beltre A. Beltre	174	367	1,243	173	338	66	7	42	131	11	222	33	13	1,403	544	115	9	9	14	21	.272	.344	.438	.782
21	Travis Jackson T. Jackson	172	362	1,343	178	387	53	17	24	66	2	141	17		1,436	546	94	25				.288	.322	.407	.729
22	Freddie Lindstrom F. Lindstrom	171	435	1,539	259	458	73	30	20	107	7	91	29		1,704	651	123	51				.298	.346	.423	.769
23	Ed Kranepool E. Kranepool	169	507	1,688	164	417	71	12	38	130	7	238	6	10	1,848	626	121	5	18	18	38	.247	.301	.371	.671
24	Mike Trout M. Trout	167	290	1,114	228	352	65	16	54	143	15	254	77	9	1,286	611	135	0	14	10	15	.316	.397	.548	.945
25	Bobby Doerr B. Doerr	167	327	1,181	167	347	59	10	19	114	2	96	8		1,333	483	88	36			17	.294	.357	.409	.766