Between the 2020 and 2029 seasons, 13 players were tied for the most runs in a game, with 5 runs. The first three are Mickey Moniak on June 24, 2023, Adolis García on April 22, 2023 and Trevor Story on May 19, 2022.

Interpreted as:

most run by a player in a regular-season game in 2020s

	NAME	R	DATE	TM		OPP	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP
1	Mickey Moniak M. Moniak	5	6/24/2023	LAA	@	COL	5	5	3	0	1	4	0	1	0	0	0	6	11	4	0	0	0	0
2	Adolis García A. García	5	4/22/2023	TEX	vs	OAK	5	5	2	0	3	8	0	1	0	0	0	6	16	5	0	0	0	0
3	Trevor Story T. Story	5	5/19/2022	BOS	vs	SEA	4	4	0	0	3	7	1	0	0	1	0	5	13	3	0	0	0	0
4	Lourdes Gurriel Jr. L. Gurriel Jr.	5	9/12/2021	TOR	@	BAL	3	2	0	0	2	7	3	0	1	0	0	6	8	2	0	0	0	0
5	Luis Urías L. Urías	5	8/12/2021	MIL	@	CHC	6	5	3	0	2	5	0	0	0	0	0	6	14	5	0	0	0	0
6	Tommy Pham T. Pham	5	7/16/2021	SDP	@	WSH	6	4	1	0	1	2	1	0	0	1	0	7	8	2	0	0	0	0
7	Bo Bichette B. Bichette	5	6/13/2021	TOR	@	BOS	5	4	1	0	1	3	1	0	0	1	0	6	8	2	0	0	0	0
8	Chris Taylor C. Taylor	5	5/2/2021	LAD	@	MIL	3	3	0	0	0	0	1	2	0	0	0	6	3	0	0	0	0	0
9	José Abreu J. Abreu	5	9/12/2020	CWS	vs	DET	4	4	0	0	2	7	1	0	0	0	0	5	10	2	0	0	0	0
10	Adam Duvall A. Duvall	5	9/9/2020	ATL	vs	MIA	4	3	0	0	3	9	2	0	1	0	0	6	12	3	0	0	0	0
11	Dansby Swanson D. Swanson	5	9/9/2020	ATL	vs	MIA	4	3	0	0	0	0	1	1	1	1	0	6	3	0	0	0	0	0
12	Austin Riley A. Riley	5	9/9/2020	ATL	vs	MIA	4	2	0	0	0	1	2	0	0	0	0	6	2	0	0	0	0	0
13	Alex Dickerson A. Dickerson	5	9/1/2020	SFG	@	COL	6	5	2	0	3	6	1	0	1	0	0	7	16	5	0	0	0	0
14	Junior Caminero J. Caminero	4	5/31/2025	TBR	@	HOU	5	4	2	0	2	5	0	0	0	0	0	5	12	4	0	0	0	0
15	Jordan Beck J. Beck	4	5/17/2025	COL	@	AZ	5	3	0	1	2	3	1	0	0	0	0	6	11	3	0	0	0	0
16	Hyeseong Kim H. Kim	4	5/15/2025	LAD	vs	ATH	3	3	1	0	0	2	2	0	0	1	0	5	4	1	0	0	0	0
17	William Contreras W. Contreras	4	5/14/2025	MIL	@	CLE	4	3	1	0	0	0	1	0	0	0	0	5	4	1	0	0	0	0
18	Javier Báez J. Báez	4	5/4/2025	DET	@	LAA	4	2	1	0	0	0	0	1	0	0	0	5	3	1	0	0	0	0
19	Ben Rice B. Rice	4	4/29/2025	NYY	@	BAL	5	3	0	0	2	2	0	1	1	0	0	6	9	2	0	0	0	0
20	Brandon Nimmo B. Nimmo	4	4/28/2025	NYM	@	WSH	6	4	1	0	2	9	0	0	0	0	0	6	11	3	0	0	0	0
21	Jesse Winker J. Winker	4	4/28/2025	NYM	@	WSH	4	2	0	0	0	1	2	0	1	0	0	6	2	0	0	0	0	0
22	Mark Vientos M. Vientos	4	4/28/2025	NYM	@	WSH	4	2	0	0	1	3	2	0	1	0	0	6	5	1	0	0	0	0
23	Kristian Campbell K. Campbell	4	4/27/2025	BOS	@	CLE	2	2	1	0	0	2	3	0	0	1	0	5	3	1	0	0	0	0
24	Eugenio Suárez E. Suárez	4	4/26/2025	AZ	vs	ATL	4	4	0	0	4	5	0	0	0	0	0	4	16	4	0	0	0	0
25	Austin Hays A. Hays	4	4/20/2025	CIN	@	BAL	6	4	1	0	0	1	1	0	0	0	0	7	5	1	0	0	0	0