Between the 1920 and 1929 seasons, Howard Ehmke gave up the most runs in a game, with 17 runs against the Yankees on September 28, 1923.
| NAME | R | DATE | TM | OPP | DEC | GS | ERA | SO | CG | SHO | SV | IP | H | ER | HR | BB | HBP | GF | IBB | TBF | WP | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | H. Ehmke | 17 | 9/28/1923 | vs | L | 1 | 24.00 | 6 | 0 | 0 | 0 | 6.0 | 21 | 16 | 2 | 4 | 0 | 0 | 42 | 0 | |||
| 2 | | H. McQuillan | 16 | 9/11/1927 | @ | L | 1 | 20.25 | 2 | 0 | 0 | 0 | 6.2 | 17 | 15 | 1 | 3 | 0 | 0 | 39 | 0 | |||
| 3 | | J. Stuart | 16 | 6/22/1925 | vs | 0 | 11.88 | 0 | 0 | 0 | 0 | 8.1 | 16 | 11 | 4 | 5 | 1 | 1 | 50 | 0 | ||||
| 4 | | T. Lyons | 16 | 7/21/1924 | @ | L | 1 | 15.75 | 3 | 1 | 0 | 0 | 8.0 | 18 | 14 | 0 | 5 | 0 | 0 | 48 | 0 | |||
| 5 | | L. O'Doul | 16 | 7/7/1923 | @ | 0 | 9.00 | 0 | 0 | 0 | 0 | 3.0 | 11 | 3 | 0 | 8 | 0 | 0 | 27 | 0 | ||||
| 6 | | J. Ring | 16 | 8/25/1922 | @ | L | 1 | 16.20 | 2 | 0 | 0 | 0 | 3.1 | 12 | 6 | 2 | 5 | 0 | 0 | 28 | 0 | |||
| 7 | | M. Gaston | 15 | 7/26/1927 | @ | L | 1 | 12.38 | 2 | 1 | 0 | 0 | 8.0 | 14 | 11 | 2 | 7 | 0 | 0 | 46 | 0 | |||
| 8 | | N. Greene | 15 | 6/20/1925 | @ | 0 | 20.25 | 0 | 0 | 0 | 0 | 6.2 | 18 | 15 | 3 | 3 | 0 | 1 | 40 | 1 | ||||
| 9 | | G. Smith | 15 | 7/7/1921 | vs | L | 1 | 4.00 | 2 | 1 | 0 | 0 | 9.0 | 20 | 4 | 0 | 2 | 1 | 0 | 49 | 0 | |||
| 10 | | J. Miljus | 14 | 7/25/1929 | @ | L | 1 | 42.00 | 0 | 0 | 0 | 0 | 3.0 | 13 | 14 | 3 | 3 | 0 | 0 | 25 | 0 | |||
| 11 | | R. Ruffing | 14 | 9/27/1928 | @ | L | 1 | 13.50 | 8 | 1 | 0 | 0 | 8.0 | 17 | 12 | 0 | 4 | 0 | 0 | 45 | 0 | |||
| 12 | | L. Stoner | 14 | 6/30/1924 | vs | L | 1 | 10.00 | 2 | 1 | 0 | 0 | 9.0 | 17 | 10 | 1 | 7 | 0 | 0 | 50 | 0 | |||
| 13 | | D. Henry | 14 | 7/22/1923 | vs | L | 1 | 8.00 | 2 | 1 | 0 | 0 | 9.0 | 17 | 8 | 0 | 4 | 1 | 0 | 50 | 1 | |||
| 14 | | J. Ring | 14 | 8/10/1922 | vs | L | 1 | 10.13 | 3 | 0 | 0 | 0 | 8.0 | 15 | 9 | 1 | 2 | 2 | 0 | 45 | 1 | |||
| 15 | | E. Vangilder | 14 | 7/25/1920 | @ | 0 | 16.71 | 2 | 0 | 0 | 0 | 7.0 | 16 | 13 | 0 | 4 | 0 | 1 | 41 | 0 | ||||
| 16 | | D. Vance | 13 | 8/2/1929 | @ | L | 1 | 15.00 | 1 | 0 | 0 | 0 | 6.0 | 18 | 10 | 1 | 1 | 0 | 0 | 37 | 0 | |||
| 17 | | B. Sherdel | 13 | 7/3/1929 | @ | L | 1 | 14.63 | 2 | 1 | 0 | 0 | 8.0 | 21 | 13 | 0 | 3 | 0 | 0 | 45 | 0 | |||
| 18 | | D. Dugan | 13 | 6/5/1929 | @ | 0 | 31.91 | 3 | 0 | 0 | 0 | 3.2 | 15 | 13 | 0 | 2 | 0 | 0 | 28 | 0 | ||||
| 19 | | T. Welzer | 13 | 9/6/1927 | vs | L | 1 | 16.71 | 5 | 0 | 0 | 0 | 7.0 | 17 | 13 | 3 | 4 | 0 | 0 | 41 | 1 | |||
| 20 | | P. Jones | 13 | 8/24/1925 | @ | L | 1 | 14.63 | 0 | 1 | 0 | 0 | 8.0 | 10 | 13 | 2 | 9 | 0 | 0 | 42 | 2 | |||
| 21 | | C. Mays | 13 | 7/17/1923 | @ | L | 1 | 14.63 | 2 | 1 | 0 | 0 | 8.0 | 20 | 13 | 1 | 4 | 1 | 0 | 44 | 0 | |||
| 22 | | L. Cadore | 13 | 9/20/1922 | vs | L | 1 | 3.00 | 1 | 1 | 0 | 0 | 9.0 | 20 | 3 | 2 | 2 | 0 | 0 | 52 | 0 | |||
| 23 | | E. Rommel | 13 | 7/4/1921 | @ | L | 1 | 15.43 | 0 | 0 | 0 | 0 | 7.0 | 14 | 12 | 2 | 4 | 0 | 0 | 40 | 2 | |||
| 24 | | B. Freeman | 13 | 6/21/1921 | @ | L | 0 | 20.65 | 1 | 0 | 0 | 0 | 5.2 | 11 | 13 | 1 | 7 | 0 | 1 | 33 | 1 | |||
| 25 | | H. Ehmke | 13 | 6/13/1921 | @ | L | 1 | 14.63 | 3 | 1 | 0 | 0 | 8.0 | 16 | 13 | 4 | 4 | 1 | 0 | 45 | 0 | |||
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