The Toronto Blue Jays allowed their most runs in a game against the California Angels on August 25, 1979, with 24 runs.

Interpreted as:

most runs allowed regular-season game by blue jays

	TEAM	R	DATE	TM		OPP	RESULT	ERA	SO	SHO	SV	IP	H	ER	HR	BB	HBP	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Blue Jays	24	8/25/1979	TOR	vs	CAL	L 2-24	19.00	4	0	0	9.0	26	19	5	5	0	0	58	1	4.00	5.00	0.80	5.00	6.9	8.6	3.44	.477	24.00	26.00
2	Blue Jays	23	9/28/2000	TOR	@	BAL	L 1-23	11.25	5	0	0	8.0	23	10	3	5	1	0	54	0	5.63	5.63	1.00	3.38	9.3	9.3	3.50	.500	25.88	25.88
3	Blue Jays	22	8/28/1992	TOR	vs	MIL	L 2-22	22.00	6	0	0	9.0	31	22	1	7	0	0	65	1	6.00	7.00	0.86	1.00	9.2	10.8	4.22	.588	22.00	31.00
4	Blue Jays	20	9/15/2020	TOR	@	NYY	L 6-20	15.75	9	0	0	8.0	16	14	6	7	2	0	50	2	10.13	7.88	1.29	6.75	18.0	14.0	2.88	.385	22.50	18.00
5	Blue Jays	19	5/25/2019	TOR	vs	SDP	L 4-19	18.00	11	0	0	9.0	20	18	7	6	3	0	54	0	11.00	6.00	1.83	7.00	20.4	11.1	2.89	.481	19.00	20.00
6	Blue Jays	19	7/9/2017	TOR	vs	HOU	L 1-19	14.00	7	0	0	9.0	17	14	5	8	1	0	54	2	7.00	8.00	0.88	5.00	13.0	14.8	2.78	.364	19.00	17.00
7	Blue Jays	19	6/24/2004	TOR	vs	TBD	L 13-19	19.00	6	0	0	9.0	24	19	3	11	1	0	61	0	6.00	11.00	0.55	3.00	9.8	18.0	3.89	.525	19.00	24.00
8	Blue Jays	19	4/16/2000	TOR	vs	SEA	L 7-19	19.00	8	0	0	9.0	22	19	5	6	2	0	55	1	8.00	6.00	1.33	5.00	14.5	10.9	3.11	.500	19.00	22.00
9	Blue Jays	18	9/11/2020	TOR	vs	NYM	L 1-18	13.00	10	0	0	9.0	19	13	3	6	2	0	55	0	10.00	6.00	1.67	3.00	18.2	10.9	2.78	.471	18.00	19.00
10	Blue Jays	18	9/13/2011	TOR	@	BOS	L 6-18	16.88	3	0	0	8.0	18	15	3	4	1	0	47	1	3.38	4.50	0.75	3.38	6.4	8.5	2.75	.417	20.25	20.25
11	Blue Jays	18	8/28/2004	TOR	vs	NYY	L 6-18	18.00	11	0	0	9.0	19	18	6	7	1	0	52	0	11.00	7.00	1.57	6.00	21.2	13.5	2.89	.481	18.00	19.00
12	Blue Jays	18	6/20/2000	TOR	vs	DET	L 6-18	18.00	3	0	0	9.0	18	18	8	9	0	0	50	0	3.00	9.00	0.33	8.00	6.0	18.0	3.00	.333	18.00	18.00
13	Blue Jays	18	9/24/1999	TOR	vs	CLE	L 4-18	17.00	6	0	0	9.0	15	17	3	9	0	0	51	0	6.00	9.00	0.67	3.00	11.8	17.6	2.67	.364	18.00	15.00
14	Blue Jays	17	4/29/2006	TOR	@	NYY	L 6-17	16.88	9	0	0	8.0	15	15	4	9	0	0	50	0	10.13	10.13	1.00	4.50	18.0	18.0	3.00	.393	19.13	16.88
15	Blue Jays	17	8/21/2005	TOR	@	DET	L 6-17	16.88	4	0	0	8.0	15	15	3	5	3	0	48	1	4.50	5.63	0.80	3.38	8.3	10.4	2.50	.364	19.13	16.88
16	Blue Jays	17	8/24/2003	TOR	vs	OAK	L 2-17	16.00	7	0	0	9.0	19	16	4	5	0	2	52	1	7.00	5.00	1.40	4.00	13.5	9.6	2.67	.417	17.00	19.00
17	Blue Jays	17	4/15/2000	TOR	vs	SEA	L 6-17	14.00	5	0	0	9.0	16	14	3	7	1	0	53	0	5.00	7.00	0.71	3.00	9.4	13.2	2.56	.351	17.00	16.00
18	Blue Jays	17	4/29/1999	TOR	@	ANA	L 1-17	19.13	4	0	0	8.0	15	17	4	7	2	0	47	1	4.50	7.88	0.57	4.50	8.5	14.9	2.75	.367	19.13	16.88
19	Blue Jays	17	4/28/1996	TOR	vs	CLE	L 3-17	16.00	5	0	0	9.0	20	16	3	3	1	0	49	0	5.00	3.00	1.67	3.00	10.2	6.1	2.56	.459	17.00	20.00
20	Blue Jays	17	5/6/1986	TOR	vs	OAK	L 3-17	13.00	4	0	0	9.0	17	13	4	4	0	0	50	0	4.00	4.00	1.00	4.00	8.0	8.0	2.33	.342	17.00	17.00
21	Blue Jays	17	6/3/1981	TOR	vs	CAL	L 6-17	15.00	4	0	0	9.0	19	15	1	6	0	0	50	0	4.00	6.00	0.67	1.00	8.0	12.0	2.78	.462	17.00	19.00
22	Blue Jays	16	6/28/2024	TOR	vs	NYY	L 5-16	14.00	8	0	0	9.0	18	14	2	2	0	0	46	1	8.00	2.00	4.00	2.00	17.4	4.3	2.22	.471	16.00	18.00
23	Blue Jays	16	8/20/2019	TOR	@	LAD	L 3-16	18.00	8	0	0	8.0	15	16	5	10	0	1	47	1	9.00	11.25	0.80	5.63	17.0	21.3	3.13	.417	18.00	16.88
24	Blue Jays	16	8/4/2017	TOR	@	HOU	L 7-16	18.00	1	0	0	8.0	18	16	5	7	0	0	47	2	1.13	7.88	0.14	5.63	2.1	14.9	3.13	.382	18.00	20.25
25	Blue Jays	16	7/25/2012	TOR	vs	OAK	L 0-16	15.00	7	0	0	9.0	14	15	3	7	0	1	48	1	7.00	7.00	1.00	3.00	14.6	14.6	2.33	.355	16.00	14.00