Antonio Senzatela and Zac Gallen are tied for allowing the most runs this season, with 67 runs.

Interpreted as:

most runs allowed by a player in one inning this regular season

	NAME	R	SEASON	TM	G	W	L	W%	GS	ERA	SO	CG	SHO	SV	IP	H	ER	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Antonio Senzatela A. Senzatela	67	2025	COL	17	3	11	.214	16	6.69	42	0	0	0	80.2	125	60	13	31	2	0	0	391	8	4.69	3.46	1.35	1.45	10.7	7.9	1.93	.370	7.48	145	5.36	127	13.95	-9.5
2	Zac Gallen Z. Gallen	67	2025	AZ	18	6	9	.400	18	5.45	98	0	0	0	104.0	100	63	20	42	2	0	1	448	1	8.48	3.63	2.33	1.73	21.9	9.4	1.37	.280	5.80	132	4.97	127	8.65	-12.8
3	Germán Márquez G. Márquez	64	2025	COL	17	3	9	.250	17	5.62	61	0	0	0	83.1	106	52	10	27	5	0	0	384	4	6.59	2.92	2.26	1.08	15.9	7.0	1.60	.342	6.91	122	4.33	102	11.45	-0.7
4	Luis Severino L. Severino	64	2025	ATH	18	2	9	.182	18	5.09	71	0	0	0	104.1	110	59	11	34	8	0	1	462	3	6.12	2.93	2.09	0.95	15.4	7.4	1.38	.293	5.52	126	4.30	105	9.49	-2.4
5	Sandy Alcantara S. Alcantara	63	2025	MIA	16	4	8	.333	16	6.98	63	0	0	0	80.0	84	62	11	34	3	0	0	360	4	7.09	3.83	1.85	1.24	17.5	9.4	1.48	.293	7.09	167	4.68	116	9.45	-5.8
6	Kyle Freeland K. Freeland	63	2025	COL	16	1	9	.100	16	5.49	61	0	0	0	83.2	112	51	9	20	2	0	1	375	1	6.56	2.15	3.05	0.97	16.3	5.3	1.58	.364	6.78	119	3.81	90	12.05	3.9
7	Trevor Williams T. Williams	59	2025	WSH	17	3	10	.231	17	6.21	65	0	0	0	82.2	106	57	11	21	2	0	0	373	1	7.08	2.29	3.10	1.20	17.4	5.6	1.54	.347	6.42	153	4.08	100	11.54	0
8	Taj Bradley T. Bradley	57	2025	TBR	17	5	6	.455	17	4.79	79	0	0	0	92.0	84	49	12	36	4	0	0	390	2	7.73	3.52	2.19	1.17	20.3	9.2	1.30	.278	5.58	124	4.37	110	8.22	-4.2
9	Jeffrey Springs J. Springs	55	2025	ATH	18	6	6	.500	16	4.07	79	0	0	0	97.1	83	44	16	37	1	0	0	412	0	7.30	3.42	2.14	1.48	19.2	9.0	1.23	.240	5.09	101	4.77	116	7.67	-7.3
10	Bailey Ober B. Ober	55	2025	MIN	17	4	6	.400	17	5.28	74	1	0	0	92.0	108	54	21	22	4	0	0	406	1	7.24	2.15	3.36	2.05	18.2	5.4	1.41	.305	5.38	131	5.29	129	10.57	-12.2
11	Ben Brown B. Brown	55	2025	CHC	16	4	6	.400	14	6.13	91	0	0	0	79.1	94	54	13	27	4	0	0	359	1	10.32	3.06	3.37	1.47	25.3	7.5	1.53	.362	6.24	154	4.09	104	10.66	-1.4
12	Brandon Pfaadt B. Pfaadt	54	2025	AZ	17	8	5	.615	17	5.38	72	0	0	0	85.1	97	51	16	21	9	0	1	377	2	7.59	2.21	3.43	1.69	19.1	5.6	1.38	.313	5.70	130	4.89	125	10.23	-9.7
13	Dylan Cease D. Cease	53	2025	SDP	18	3	8	.273	18	4.62	121	0	0	0	97.1	93	50	12	36	3	0	1	419	2	11.19	3.33	3.36	1.11	28.9	8.6	1.33	.328	4.90	118	3.40	85	8.60	6.4
14	Michael Lorenzen M. Lorenzen	53	2025	KCR	17	4	8	.333	17	4.95	78	0	0	0	92.2	99	51	17	28	2	0	0	400	10	7.58	2.72	2.79	1.65	19.5	7.0	1.37	.298	5.15	117	4.76	116	9.62	-6.8
15	Jake Irvin J. Irvin	53	2025	WSH	17	6	3	.667	17	4.73	71	0	0	0	99.0	99	52	19	30	3	0	0	423	1	6.45	2.73	2.37	1.73	16.8	7.1	1.30	.267	4.82	117	5.14	126	9.00	-11.7
16	Jack Kochanowicz J. Kochanowicz	53	2025	LAA	17	3	8	.273	17	5.44	61	0	0	0	86.0	94	52	15	40	6	0	2	376	3	6.38	4.19	1.53	1.57	16.2	10.6	1.56	.311	5.55	132	5.54	131	9.84	-12.1
17	Chase Dollander C. Dollander	52	2025	COL	14	2	9	.182	14	6.65	50	0	0	0	65.0	69	48	15	29	2	0	0	290	1	6.92	4.02	1.72	2.08	17.2	10.0	1.51	.278	7.20	144	5.98	141	9.55	-11.9
18	Chris Paddack C. Paddack	51	2025	MIN	17	3	7	.300	17	4.70	63	0	0	0	90.0	87	47	13	24	3	0	0	380	2	6.30	2.40	2.63	1.30	16.6	6.3	1.23	.267	5.10	116	4.46	109	8.70	-3.6
19	Mitchell Parker M. Parker	51	2025	WSH	17	5	8	.385	17	4.63	62	0	0	0	91.1	87	47	11	36	3	0	0	393	2	6.11	3.55	1.72	1.08	15.8	9.2	1.35	.270	5.03	114	4.57	112	8.57	-5
20	Walker Buehler W. Buehler	50	2025	BOS	14	5	6	.455	14	6.45	59	0	0	0	67.0	74	48	15	32	8	0	0	307	0	7.93	4.30	1.84	2.01	19.2	10.4	1.58	.306	6.72	151	6.02	146	9.94	-13.9
21	Erick Fedde E. Fedde	50	2025	STL	17	3	8	.273	17	4.56	57	1	1	0	92.2	91	47	10	41	2	0	1	400	1	5.54	3.98	1.39	0.97	14.3	10.3	1.42	.279	4.86	114	4.65	118	8.84	-7.4
22	Jack Flaherty J. Flaherty	49	2025	DET	17	5	9	.357	17	4.84	109	0	0	0	89.1	74	48	16	37	3	0	0	374	1	10.98	3.73	2.95	1.61	29.1	9.9	1.24	.278	4.94	121	4.32	106	7.46	-2.6
23	JP Sears	49	2025	ATH	17	6	7	.462	17	5.09	67	0	0	0	86.2	91	49	18	22	5	0	0	372	1	6.96	2.28	3.05	1.87	18.0	5.9	1.30	.281	5.09	126	5.17	126	9.45	-10.3
24	Tanner Bibee T. Bibee	49	2025	CLE	17	4	9	.308	17	4.20	87	1	0	0	98.2	92	46	15	30	7	0	1	415	2	7.94	2.74	2.90	1.37	21.0	7.2	1.24	.279	4.47	105	4.42	109	8.39	-4.1
25	Will Warren W. Warren	49	2025	NYY	18	5	4	.556	18	5.02	107	0	0	0	84.1	81	47	8	39	2	0	0	373	2	11.42	4.16	2.74	0.85	28.7	10.5	1.42	.336	5.23	124	3.24	77	8.64	9