The Minnesota Twins put up the most runs by a team in a loss in 2021, with 14 runs against the Tigers on July 28, 2021.

Interpreted as:

most runs by a team in a regular-season loss 2021

	TEAM	R	L	DATE	TM		OPP	RESULT	W	L%	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Twins	14	1	7/28/2021	MIN	vs	DET	L 14-17	0	1.000	43	16	1	0	7	14	7	1	8	0	0	51	38	8	0	0	0	0	.372	.471	.884	1.354
2	Cubs	13	1	8/27/2021	CHC	@	CWS	L 13-17	0	1.000	39	13	3	0	4	12	3	0	12	0	2	42	28	7	0	0	0	0	.333	.381	.718	1.099
3	Phillies	12	1	6/23/2021	PHI	vs	WSH	L 12-13	0	1.000	43	15	2	0	3	12	6	1	5	1	0	50	26	5	0	0	0	0	.349	.440	.605	1.045
4	Cubs	12	1	5/2/2021	CHC	@	CIN	L 12-13	0	1.000	42	14	4	0	5	12	3	0	9	2	2	45	33	9	0	0	1	0	.333	.378	.786	1.163
5	Twins	12	1	4/21/2021	MIN	@	OAK	L 12-13	0	1.000	49	18	4	0	4	10	2	0	10	1	0	51	34	8	0	0	0	1	.367	.392	.694	1.086
6	White Sox	11	1	7/31/2021	CWS	vs	CLE	L 11-12	0	1.000	38	11	2	0	5	10	5	0	7	0	0	43	28	7	0	0	0	1	.289	.372	.737	1.109
7	Reds	11	1	7/19/2021	CIN	vs	NYM	L 11-15	0	1.000	50	16	5	0	0	10	4	2	11	0	0	57	21	5	0	1	0	1	.320	.386	.420	.806
8	Angels	11	1	5/8/2021	LAA	vs	LAD	L 11-14	0	1.000	37	11	1	0	1	10	4	0	8	0	0	42	15	2	0	1	0	1	.297	.357	.405	.763
9	Reds	11	1	4/22/2021	CIN	vs	ARI	L 11-14	0	1.000	44	13	1	0	6	11	4	0	13	0	0	48	32	7	0	0	0	0	.295	.354	.727	1.081
10	Royals	10	1	9/15/2021	KCR	vs	OAK	L 10-12	0	1.000	42	17	2	0	1	10	4	2	10	1	0	48	22	3	0	0	0	1	.405	.479	.524	1.003
11	Orioles	10	1	9/11/2021	BAL	vs	TOR	L 10-11	0	1.000	36	14	3	0	4	10	3	0	7	0	0	39	29	7	0	0	1	0	.389	.436	.806	1.241
12	Red Sox	10	1	9/6/2021	BOS	vs	TBR	L 10-11	0	1.000	42	14	4	1	1	10	7	1	10	0	0	51	23	6	0	1	3	2	.333	.431	.548	.979
13	Athletics	10	1	9/3/2021	OAK	@	TOR	L 10-11	0	1.000	38	11	3	0	2	10	3	2	5	0	0	43	20	5	0	0	0	1	.289	.372	.526	.898
14	Cubs	10	1	8/25/2021	CHC	vs	COL	L 10-13	0	1.000	41	11	1	0	1	8	2	1	11	2	0	44	15	2	0	0	1	1	.268	.318	.366	.684
15	Tigers	10	1	8/19/2021	DET	vs	LAA	L 10-13	0	1.000	41	14	4	0	3	10	1	1	8	1	1	43	27	7	0	0	0	0	.341	.372	.659	1.031
16	Cubs	10	1	8/13/2021	CHC	@	MIA	L 10-14	0	1.000	44	18	4	1	4	10	4	1	13	0	0	50	36	9	0	1	0	0	.409	.460	.818	1.278
17	Cubs	10	1	7/6/2021	CHC	vs	PHI	L 10-15	0	1.000	39	14	3	0	3	10	1	1	12	0	0	43	26	6	0	2	0	0	.359	.372	.667	1.039
18	Indians	10	1	6/18/2021	CLE	@	PIT	L 10-11	0	1.000	35	12	0	0	1	9	3	3	9	0	0	41	15	1	0	0	0	3	.343	.439	.429	.868
19	Rangers	10	1	4/1/2021	TEX	@	KCR	L 10-14	0	1.000	40	15	3	0	0	9	9	1	16	1	0	50	18	3	0	0	0	0	.375	.500	.450	.950
20	Padres	9	1	9/29/2021	SDP	@	LAD	L 9-11	0	1.000	40	13	2	1	2	8	3	0	9	1	2	43	23	5	0	0	0	0	.325	.372	.575	.947
21	Nationals	9	1	9/4/2021	WSH	vs	NYM	L 9-11	0	1.000	38	13	3	0	1	8	5	0	7	0	0	45	19	4	0	2	1	1	.342	.400	.500	.900
22	Twins	9	1	8/24/2021	MIN	@	BOS	L 9-11	0	1.000	39	14	2	1	2	9	5	1	11	0	1	45	24	5	0	0	0	1	.359	.444	.615	1.060
23	Marlins	9	1	8/18/2021	MIA	vs	ATL	L 9-11	0	1.000	38	12	1	0	1	9	3	1	12	0	0	43	16	2	0	1	0	0	.316	.372	.421	.793
24	Tigers	9	1	7/11/2021	DET	@	MIN	L 9-12	0	1.000	37	8	1	0	2	9	6	0	14	0	1	43	15	3	0	0	1	0	.216	.326	.405	.731
25	Orioles	9	1	5/22/2021	BAL	@	WSH	L 9-12	0	1.000	38	12	5	0	2	9	4	0	11	0	0	42	23	7	0	0	0	1	.316	.381	.605	.986