most runs in a game by a team against the white sox

The New York Yankees have the most runs by a team in a game against the White Sox, with 22 runs on July 26, 1931.

Interpreted as:

most runs in a regular-season game by a team against the white sox

	TEAM	R	DATE	TM		OPP	RESULT	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	22	7/26/1931	NYY	vs	CWS	W 22-5	39	17	1	0	0	21	12	0	2	3	0	52	18	1	1				.436	.569	.462	1.030
2	Astros	21	8/18/2022	HOU	@	CWS	W 21-5	51	25	5	0	4	21	4	0	9	1	0	55	42	9	0	0	0	1	.490	.527	.824	1.351
3	Red Sox	21	8/30/1970	BOS	@	CWS	W 21-11	47	22	5	1	2	21	10	0	5	2	0	57	35	8	0	0	1	1	.468	.561	.745	1.306
4	Tigers	21	7/1/1936	DET	@	CWS	W 21-6	53	25	2	1	1	19	6	0	2	1	1	60	32	4	1				.472	.525	.604	1.129
5	Athletics	21	8/9/1923	PHA	vs	CWS	W 21-5	44	22	3	1	2	19	7	0	4	1	0	51	33	6	0				.500	.569	.750	1.319
6	Orioles	21	8/25/1902	BAL	vs	CWS	W 21-6	49	25	5	3	1	19	3	3	-8	2	-9	55	39	9	0		-9	-9	.510	.564	.796	1.360
7	Brewers	21	5/5/1901	MIL	vs	CWS	W 21-7	53	25	6	1	1	18	2	0	-10	2	-10	57	36	8	2		-10	-10	.472	.491	.679	1.170
8	Twins	20	5/21/2009	MIN	@	CWS	W 20-1	46	20	4	0	4	18	5	1	5	0	0	54	36	8	1	1	1	0	.435	.491	.783	1.273
9	Twins	20	7/6/2007	MIN	@	CWS	W 20-14	47	21	4	0	2	20	8	0	1	0	0	57	31	6	0	2	1	1	.447	.509	.660	1.168
10	Rangers	20	4/2/1998	TEX	vs	CWS	W 20-4	46	23	2	0	5	19	3	0	6	0	0	50	40	7	0	1	0	2	.500	.520	.870	1.390
11	Yankees	20	7/17/1920	NYY	vs	CWS	W 20-5	46	22	7	2	3	17	0	0	0	0	0	48	42	12	2				.478	.478	.913	1.391
12	Indians	19	6/28/2013	CLE	@	CWS	W 19-10	47	21	8	1	1	18	9	1	11	2	0	57	34	10	0	0	0	1	.447	.544	.723	1.267
13	Angels	19	5/10/2002	ANA	vs	CWS	W 19-0	49	24	4	0	5	19	4	2	5	0	0	56	43	9	1	0	0	0	.490	.545	.878	1.423
14	Twins	19	6/26/1977	MIN	vs	CWS	W 19-12	39	18	4	1	2	17	11	0	6	0	1	52	30	7	1	1	1	0	.462	.569	.769	1.338
15	Red Sox	19	5/13/1947	BSA	vs	CWS	W 19-6	40	18	3	3	3	17	11	0	3	0	1	53	36	9	2			0	.450	.569	.900	1.469
16	Red Sox	19	8/27/1938	BSA	vs	CWS	W 19-6	46	22	6	1	1	17	6	0	3	0	0	53	33	8	1				.478	.538	.717	1.256
17	Athletics	19	9/13/1935	PHA	vs	CWS	W 19-7	40	19	2	0	2	19	9	1	3	0	1	51	27	4	1				.475	.580	.675	1.255
18	Twins	18	9/4/2012	MIN	@	CWS	W 18-9	41	17	0	1	2	18	8	0	7	0	0	51	25	3	0	2	0	1	.415	.490	.610	1.100
19	Tigers	18	9/4/2011	DET	vs	CWS	W 18-2	48	24	5	0	2	17	3	1	12	0	0	52	35	7	0	0	0	0	.500	.538	.729	1.268
20	Yankees	18	8/3/2011	NYY	@	CWS	W 18-7	48	23	4	2	2	18	2	1	9	1	0	52	37	8	0	1	0	1	.479	.500	.771	1.271
21	Twins	18	5/16/2003	MIN	vs	CWS	W 18-3	43	20	4	0	4	18	4	0	4	0	0	48	36	8	1	0	0	0	.465	.511	.837	1.348
22	Twins	18	9/5/1976	MIN	vs	CWS	W 18-1	43	22	4	1	2	17	7	0	0	2	1	52	34	7	1	1	0	0	.512	.569	.791	1.359
23	Yankees	18	8/31/1974	NYY	@	CWS	W 18-6	50	25	4	0	1	15	5	1	4	1	0	57	32	5	0	1	1	1	.500	.544	.640	1.184
24	Yankees	18	6/3/1972	NYY	@	CWS	W 18-10	59	18	2	0	3	16	10	0	8	5	0	69	29	5	0	0	0	0	.305	.406	.492	.897
25	Orioles	18	4/29/1970	BAL	@	CWS	W 18-2	48	20	2	0	5	17	7	0	5	0	0	55	37	7	0	0	0	0	.417	.491	.771	1.262