Since 1950, the Chicago Cubs have their most runs in a game against the Rockies on August 18, 1995, with 26 runs.

Interpreted as:

most runs in a regular-season game by cubs since 1950

	TEAM	R	DATE	TM		OPP	RESULT	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Cubs	26	8/18/1995	CHC	@	COL	W 26-7	54	27	7	1	3	26	6	0	8	0	0	60	45	11	0	0	0	1	.500	.550	.833	1.383
2	Cubs	23	5/17/1977	CHC	vs	SDP	W 23-6	50	24	4	0	7	22	5	1	0	0	0	57	49	11	1	0	0	1	.480	.536	.980	1.516
3	Cubs	23	4/17/1954	CHC	vs	STL	W 23-13	44	20	7	0	2	21	12	0	1	0	0	57	33	9	0	1	1	2	.455	.561	.750	1.311
4	Cubs	22	6/3/1987	CHC	vs	HOU	W 22-7	44	21	3	0	6	21	9	0	6	1	0	54	42	9	0	1	0	1	.477	.556	.955	1.510
5	Cubs	22	5/17/1979	CHC	vs	PHI	L 22-23	56	26	3	1	6	22	3	0	4	0	0	59	49	10	0	0	0	2	.464	.492	.875	1.367
6	Cubs	21	4/23/2022	CHC	vs	PIT	W 21-0	48	23	4	0	1	19	4	1	3	2	0	53	30	5	0	0	0	1	.479	.528	.625	1.153
7	Cubs	20	8/1/2023	CHC	vs	CIN	W 20-9	43	21	4	0	7	19	4	1	6	3	0	49	46	11	0	1	0	1	.488	.531	1.070	1.600
8	Cubs	20	5/5/2001	CHC	vs	LAD	W 20-1	39	18	2	0	3	17	9	0	13	0	1	50	29	5	2	0	0	2	.462	.563	.744	1.306
9	Cubs	20	5/20/1967	CHC	vs	LAD	W 20-3	38	14	3	0	3	19	6	2	3	1	0	48	26	6	0	2	0	0	.368	.458	.684	1.143
10	Cubs	20	8/13/1959	CHC	vs	SFG	W 20-9	41	19	2	2	5	20	13	1	2	0	0	56	40	9	1	0	4	0	.463	.600	.976	1.576
11	Cubs	19	4/30/2008	CHC	vs	MIL	W 19-5	42	17	5	0	2	19	9	0	9	1	0	51	28	7	0	0	0	0	.405	.510	.667	1.176
12	Cubs	19	9/21/1974	CHC	@	STL	W 19-4	43	18	1	0	2	17	9	1	2	0	1	55	25	3	0	2	0	0	.419	.509	.581	1.090
13	Cubs	19	5/13/1969	CHC	vs	SDP	W 19-0	39	15	3	2	4	17	12	1	7	0	0	53	34	9	1	0	0	1	.385	.538	.872	1.410
14	Cubs	18	3/31/2025	CHC	@	ATH	W 18-3	48	21	6	1	4	18	10	1	7	0	0	60	41	11	0	1	0	0	.438	.533	.854	1.388
15	Cubs	18	8/26/2024	CHC	@	PIT	W 18-8	46	21	7	0	2	18	7	2	7	8	0	56	34	9	0	1	1	1	.457	.536	.739	1.275
16	Cubs	18	4/17/1974	CHC	vs	PIT	W 18-9	38	13	4	0	6	17	9	0	3	0	0	47	35	10	0	0	0	1	.342	.468	.921	1.389
17	Cubs	18	9/16/1972	CHC	vs	NYM	W 18-5	40	17	3	0	5	18	15	0	7	0	0	57	35	8	1	1	2	0	.425	.571	.875	1.446
18	Cubs	18	6/11/1967	CHC	vs	NYM	W 18-10	43	19	1	2	7	18	2	0	6	1	1	46	45	10	0	1	0	0	.442	.457	1.047	1.503
19	Cubs	18	5/18/1951	CHC	vs	PHN	W 18-9	39	17	7	0	3	18	9	0	5	1	1	48	33	10	0		0	1	.436	.542	.846	1.388
20	Cubs	17	7/18/2023	CHC	vs	WSH	W 17-3	41	20	1	0	2	16	4	1	9	1	0	47	27	3	0	1	1	1	.488	.532	.659	1.190
21	Cubs	17	9/13/2019	CHC	vs	PIT	W 17-8	40	16	3	0	5	17	10	1	9	0	0	51	34	8	0	0	0	0	.400	.529	.850	1.379
22	Cubs	17	9/13/2017	CHC	vs	NYM	W 17-5	38	16	3	1	2	17	11	0	9	0	0	51	27	6	2	0	1	0	.421	.551	.711	1.262
23	Cubs	17	8/30/2017	CHC	vs	PIT	W 17-3	45	20	4	0	4	16	1	1	9	2	0	47	36	8	0	0	0	0	.444	.468	.800	1.268
24	Cubs	17	8/26/2017	CHC	@	PHI	W 17-2	41	14	3	0	6	17	5	1	9	0	0	47	35	9	0	0	0	0	.341	.426	.854	1.279
25	Cubs	17	6/17/2015	CHC	@	CLE	W 17-0	43	18	2	1	4	16	5	1	6	0	0	49	34	7	0	0	0	2	.419	.490	.791	1.280