11 players are tied for the most runs for the White Sox in a game, with 5 runs. The first three are José Abreu on September 12, 2020, Yoán Moncada on September 14, 2017 and Tim Raines on April 18, 1994.
Interpreted as:
most runs in a regular-season game by white sox individual| NAME | R | DATE | TM | OPP | AB | H | 2B | 3B | HR | RBI | BB | HBP | SO | SB | CS | PA | TB | XBH | SH | SF | IBB | GIDP | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | J. Abreu | 5 | 9/12/2020 |  CWS | vs |  DET | 4 | 4 | 0 | 0 | 2 | 7 | 1 | 0 | 0 | 0 | 0 | 5 | 10 | 2 | 0 | 0 | 0 | 0 |
| 2 |  | Y. Moncada | 5 | 9/14/2017 | CWS | @ | DET | 5 | 4 | 0 | 0 | 1 | 1 | 2 | 0 | 1 | 1 | 0 | 7 | 7 | 1 | 0 | 0 | 0 | 0 |
| 3 | | T. Raines | 5 | 4/18/1994 | CWS | @ |  BOS | 5 | 4 | 0 | 0 | 3 | 4 | 1 | 0 | 0 | 0 | 0 | 6 | 13 | 3 | 0 | 0 | 1 | 0 |
| 4 | | W. Williams | 5 | 5/31/1970 | CWS | @ |  BOS | 7 | 5 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 7 | 6 | 1 | 0 | 0 | 0 | 0 |
| 5 | | T. Agee | 5 | 4/21/1966 | CWS | @ |  CAL | 3 | 2 | 0 | 0 | 1 | 1 | 2 | 1 | 1 | 1 | 0 | 6 | 5 | 1 | 0 | 0 | 0 | 0 |
| 6 | | C. Carrasquel | 5 | 4/23/1955 | CWS | @ |  KCA | 6 | 5 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 7 | 5 | 0 | 0 | 0 | 0 | 0 |
| 7 | | M. Minoso | 5 | 4/23/1955 | CWS | @ | KCA | 6 | 4 | 1 | 0 | 1 | 5 | 1 | 0 | 0 | 1 | 0 | 7 | 8 | 2 | 0 | 0 | 1 | 0 |
| 8 | | J. Mostil | 5 | 6/30/1924 | CWS | @ | DET | 2 | 2 | 1 | 0 | 0 | 1 | 4 | 0 | 0 | 0 | 0 | 6 | 3 | 1 | 0 | |||
| 9 | | E. Sheely | 5 | 9/9/1921 | CWS | vs | DET | 5 | 5 | 0 | 1 | 1 | 5 | 0 | 0 | 0 | 0 | 0 | 5 | 10 | 2 | 0 | |||
| 10 | | R. Zeider | 5 | 10/8/1911 | CWS | vs |  CLE | 5 | 4 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 5 | 7 | 1 | 0 | |||||
| 11 | | J. Donahue | 5 | 6/27/1904 | CWS | @ | DET | 5 | 4 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 6 | 6 | 1 | 0 | ||||
| 12 |  | L. Robert Jr. | 4 | 5/7/2023 | CWS | @ |  CIN | 2 | 2 | 1 | 0 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 4 | 3 | 1 | 0 | 0 | 0 | 0 |
| 13 | | A. Vaughn | 4 | 4/8/2023 | CWS | @ |  PIT | 3 | 2 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 5 | 2 | 0 | 0 | 0 | 0 | 0 |
| 14 |  | T. Anderson | 4 | 4/7/2023 | CWS | @ | PIT | 5 | 4 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 5 | 6 | 2 | 0 | 0 | 0 | 0 |
| 15 | | T. Anderson | 4 | 8/20/2021 | CWS | @ |  TBR | 6 | 3 | 0 | 0 | 1 | 2 | 0 | 0 | 2 | 0 | 0 | 6 | 6 | 1 | 0 | 0 | 0 | 0 |
| 16 | | S. Zavala | 4 | 7/31/2021 | CWS | vs |  CLE | 4 | 4 | 0 | 0 | 3 | 6 | 0 | 0 | 0 | 0 | 0 | 4 | 13 | 3 | 0 | 0 | 0 | 0 |
| 17 | | T. Anderson | 4 | 4/5/2019 | CWS | vs |  SEA | 4 | 3 | 0 | 0 | 1 | 3 | 1 | 0 | 0 | 0 | 0 | 5 | 6 | 1 | 0 | 0 | 0 | 0 |
| 18 |  | M. Davidson | 4 | 4/5/2018 | CWS | vs | DET | 3 | 2 | 1 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 5 | 3 | 1 | 0 | 0 | 0 | 0 |
| 19 | | M. Davidson | 4 | 3/29/2018 | CWS | @ |  KCR | 4 | 3 | 0 | 0 | 3 | 5 | 1 | 0 | 0 | 0 | 0 | 5 | 12 | 3 | 0 | 0 | 0 | 0 |
| 20 | | M. Cabrera | 4 | 9/4/2016 | CWS | @ |  MIN | 6 | 3 | 1 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 7 | 4 | 1 | 0 | 0 | 0 | 0 |
| 21 |  | A. Eaton | 4 | 9/2/2016 | CWS | @ | MIN | 5 | 4 | 1 | 0 | 0 | 1 | 1 | 0 | 1 | 0 | 0 | 6 | 5 | 1 | 0 | 0 | 1 | 0 |
| 22 | | J. Rollins | 4 | 5/10/2016 | CWS | @ |  TEX | 4 | 3 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 5 | 5 | 1 | 0 | 0 | 0 | 0 |
| 23 | | A. De Aza | 4 | 6/28/2013 | CWS | vs | CLE | 5 | 3 | 1 | 0 | 0 | 2 | 1 | 0 | 1 | 2 | 0 | 6 | 4 | 1 | 0 | 0 | 0 | 0 |
| 24 | | D. Viciedo | 4 | 10/3/2012 | CWS | @ | CLE | 4 | 3 | 1 | 0 | 1 | 1 | 1 | 0 | 1 | 0 | 0 | 5 | 7 | 2 | 0 | 0 | 0 | 0 |
| 25 |  | J. Thome | 4 | 4/19/2009 | CWS | @ | TBR | 3 | 2 | 1 | 0 | 1 | 2 | 2 | 0 | 0 | 0 | 0 | 5 | 6 | 2 | 0 | 0 | 0 | 0 |
Results may be incomplete. StatMuse has complete game-level data for runs going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
Guardians 
CHC 
Yankees 
Red Sox 
Astros 
Mets 
Phillies 
Cardinals 
Dodgers 
Padres 
WSH 
AZ 
BAL 
TOR 
MIA 
