Between the 2000 and 2015 seasons, Mariano Rivera had the most saves, with 523 saves.

Interpreted as:

most regular-season saves by a player from 2000 to 2015

	NAME	SV	G	W	L	W%	GS	ERA	SO	CG	SHO	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Mariano Rivera M. Rivera	523	849	56	47	.544	0	2.05	836	0	0	907.0	698	207	227	49	167	38	768	28	3,562	8	8.30	1.66	5.01	0.49	23.5	4.7	0.95	.263	2.25	46	2.61	59	6.93	180.9
2	Francisco Rodriguez F. Rodriguez	386	859	47	44	.516	0	2.69	1,067	0	0	892.1	662	267	289	83	357	15	602	40	3,658	62	10.76	3.60	2.99	0.84	29.2	9.8	1.14	.271	2.91	65	3.15	76	6.68	102.2
3	Joe Nathan J. Nathan	376	758	55	30	.647	15	2.74	913	0	0	826.2	601	252	272	67	294	22	584	31	3,348	44	9.94	3.20	3.11	0.73	27.3	8.8	1.08	.260	2.96	64	3.08	73	6.54	106.2
4	Trevor Hoffman T. Hoffman	373	596	25	47	.347	0	3.02	553	0	0	580.1	481	195	211	54	143	5	502	23	2,347	19	8.58	2.22	3.87	0.84	23.6	6.1	1.08	.268	3.27	75	3.15	75	7.46	71.8
5	Jonathan Papelbon J. Papelbon	349	652	39	32	.549	3	2.35	777	0	0	690.2	535	180	208	54	171	34	555	15	2,786	13	10.13	2.23	4.54	0.70	27.9	6.1	1.02	.275	2.71	56	2.76	68	6.97	103.5
6	Francisco Cordero F. Cordero	329	780	45	51	.469	0	3.38	777	0	0	805.2	732	303	335	62	357	27	571	28	3,460	36	8.68	3.99	2.18	0.69	22.5	10.3	1.35	.300	3.74	75	3.58	81	8.18	77.2
7	Billy Wagner B. Wagner	321	629	30	26	.536	0	2.30	802	0	0	650.0	443	166	190	60	192	26	529	21	2,577	35	11.10	2.66	4.18	0.83	31.1	7.5	0.98	.256	2.63	53	2.81	64	6.13	111.4
8	Huston Street H. Street	315	638	39	32	.549	0	2.85	648	0	0	653.2	509	207	221	65	170	8	502	35	2,598	20	8.92	2.34	3.81	0.89	24.9	6.5	1.04	.260	3.04	68	3.22	79	7.01	66.4
9	Jason Isringhausen J. Isringhausen	291	644	33	33	.500	0	3.18	585	0	0	648.2	519	229	256	54	277	20	479	32	2,740	28	8.12	3.84	2.11	0.75	21.4	10.1	1.23	.258	3.55	76	3.72	87	7.20	40.3
10	Jose Valverde J. Valverde	288	626	27	33	.450	0	3.27	692	0	0	630.1	490	229	255	67	264	26	520	31	2,646	24	9.88	3.77	2.62	0.96	26.2	10.0	1.20	.265	3.64	76	3.65	85	7.00	45.6
11	Fernando Rodney F. Rodney	236	700	37	55	.402	0	3.71	685	0	0	700.1	612	289	319	53	341	42	440	30	3,055	41	8.80	4.38	2.01	0.68	22.4	11.2	1.36	.289	4.10	89	3.76	90	7.86	31.7
12	Armando Benitez A. Benitez	230	478	25	28	.472	0	3.12	535	0	0	487.1	356	169	188	64	233	5	378	19	2,026	11	9.88	4.30	2.30	1.18	26.4	11.5	1.21	.246	3.47	73	4.04	94	6.57	14.6
13	Craig Kimbrel C. Kimbrel	225	355	19	12	.613	0	1.63	563	0	0	348.1	193	63	70	18	130	9	294	5	1,366	26	14.55	3.36	4.33	0.47	41.2	9.5	0.93	.271	1.81	44	1.71	46	4.99	79.8
14	Brad Lidge B. Lidge	225	603	26	32	.448	1	3.54	799	0	0	603.1	492	237	257	57	287	34	368	41	2,589	46	11.92	4.28	2.78	0.85	30.9	11.1	1.29	.308	3.83	82	3.26	75	7.34	72.7
15	Troy Percival T. Percival	219	397	21	21	.500	1	3.37	370	0	0	385.0	281	144	157	51	168	14	322	13	1,599	17	8.65	3.93	2.20	1.19	23.1	10.5	1.17	.231	3.67	76	4.28	97	6.57	6.3
16	Rafael Soriano R. Soriano	207	591	24	28	.462	8	2.89	641	0	0	636.1	489	204	213	62	197	15	343	20	2,571	13	9.07	2.79	3.25	0.88	24.9	7.7	1.08	.258	3.01	71	3.34	81	6.92	58.6
17	Brian Fuentes B. Fuentes	204	650	26	43	.377	0	3.62	639	0	0	613.1	515	247	267	64	258	52	381	25	2,622	32	9.38	3.79	2.48	0.94	24.4	9.8	1.26	.280	3.92	81	3.86	88	7.56	37.4
18	Joakim Soria J. Soria	202	444	19	20	.487	0	2.57	481	0	0	451.0	353	129	138	36	126	18	325	11	1,833	18	9.60	2.51	3.82	0.72	26.2	6.9	1.06	.270	2.75	61	2.97	72	7.04	59.3
19	Bob Wickman B. Wickman	193	383	13	24	.351	0	3.08	303	0	0	370.2	364	127	147	27	121	11	317	14	1,589	8	7.36	2.94	2.50	0.66	19.1	7.6	1.31	.299	3.57	69	3.46	78	8.84	40.7
20	Todd Jones T. Jones	191	590	30	39	.435	1	4.30	449	0	0	605.1	660	289	316	56	212	21	348	26	2,640	19	6.68	3.15	2.12	0.83	17.0	8.0	1.44	.318	4.70	94	3.94	88	9.81	35.3
21	J.J. Putz	189	572	37	33	.529	0	3.08	599	0	0	566.2	469	194	203	50	184	19	357	18	2,329	24	9.51	2.92	3.26	0.79	25.7	7.9	1.15	.284	3.22	73	3.20	76	7.45	63.2
22	Eric Gagne E. Gagne	187	397	32	25	.561	43	3.53	688	0	0	613.2	500	241	260	73	211	33	269	13	2,545	17	10.09	3.09	3.26	1.07	27.0	8.3	1.16	.277	3.81	84	3.56	81	7.33	55.9
23	Jose Mesa J. Mesa	184	532	26	40	.394	0	4.38	394	0	0	532.2	555	259	280	58	238	23	359	25	2,363	27	6.66	4.02	1.66	0.98	16.7	10.1	1.49	.301	4.73	99	4.47	101	9.38	-3.8
24	Keith Foulke K. Foulke	178	471	31	27	.534	0	3.04	484	0	0	542.2	441	183	189	61	130	33	352	15	2,197	9	8.03	2.16	3.72	1.01	22.0	5.9	1.05	.255	3.13	66	3.63	81	7.31	53.2
25	Eddie Guardado E. Guardado	178	540	28	27	.509	0	3.52	442	0	0	508.1	437	199	212	74	160	8	327	19	2,097	13	7.83	2.83	2.76	1.31	21.1	7.6	1.17	.257	3.75	77	4.20	95	7.74	12.2