Babe Ruth has scored the most career runs in starts, with 2,174 runs.

Interpreted as:

most scoring by a starting by a player lineup

	NAME	R	GS	G	W	L	W%	ERA	SO	CG	SHO	SV	IP	H	ER	HR	BB	HBP	GF	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Babe Ruth B. Ruth	2,174	147	163	94	46	.671	2.28	488	107	17	4	1221.1	974	309	10	441	29	12	4,896	25	3.60	3.25	1.11	0.07	10.0	9.0	1.16	.245	2.95	82	2.81	100	7.18	-6.6
2	Jimmie Foxx J. Foxx	1,751	2	10	1	0	1.000	1.52	11	0	0	0	23.2	13	4	0	14	1	8	97	0	4.18	5.32	0.79	0.00	11.3	14.4	1.14	.183	1.52	40	3.53	96	4.94	0.4
3	Jesse Burkett J. Burkett	1,720	14	23	3	11	.214	5.56	84	6	0	0	123.0	144	76	3	94	14	8	617	16	6.15	6.88	0.89	0.22	13.6	15.2	1.93	.334	9.44	156	4.53	119	10.54	-10
4	Jimmy Ryan J. Ryan	1,643	5	24	6	1	.857	3.62	43	3	0	2	117.0	133	47	8	44		16	501	6	3.31	3.38	0.98	0.62	8.6	8.8	1.51	.313	6.54	99	4.41	116	10.23	-5.1
5	George Van Haltren G. Van Haltren	1,642	68	93	40	31	.563	4.05	281	65	5	4	689.1	809	310	34	244	57	23	3,141	46	3.67	3.19	1.15	0.44	8.9	7.8	1.53	.307	6.88	108	4.00	103	10.56	0.6
6	Jake Beckley J. Beckley	1,602	1	1	0	1	.000	6.75	2	0	0	0	4.0	9	3	0	1	0	0	21	0	4.50	2.25	2.00	0.00	9.5	4.8	2.50	.500	18.00	223	2.42	76	20.25	0.4
7	Dan Brouthers D. Brouthers	1,523	2	4	0	2	.000	7.83	8	2	0	0	23.0	44	20	0	11		1	127	4	3.13	4.30	0.73	0.00	6.3	8.7	2.39		14.48	291	3.52	138	17.22	-2.6
8	Tom Brown T. Brown	1,521	1	12	2	2	.500	5.29	16	1	0	0	49.1	56	29	0	31		11	265	14	2.92	5.66	0.52	0.00	6.0	11.7	1.76	.260	10.03	172	4.55	152	10.22	-9.7
9	Sam Rice S. Rice	1,514	3	9	1	1	.500	2.52	12	1	0	0	39.1	31	11	0	19	0	4	156	1	2.75	4.35	0.63	0.00	7.7	12.2	1.27	.248	4.12	89	3.20	112	7.09	-1.6
10	John Ward J. Ward	1,410	262	293	164	103	.614	2.10	920	245	24	3	2469.2	2,324	576	26	253		32	10,164	144	3.35	0.92	3.64	0.09	9.1	2.5	1.04		4.32	82	2.43	96	8.47	9.1
11	George Sisler G. Sisler	1,284	12	24	5	6	.455	2.35	63	9	1	3	111.0	91	29	0	52	6	8	453	2	5.11	4.22	1.21	0.00	13.9	11.5	1.29	.274	2.92	83	2.84	98	7.38	0.7
12	Ben Chapman B. Chapman	1,144	16	25	8	6	.571	4.39	65	8	0	0	141.1	147	69	7	71	6	7	642	3	4.14	4.52	0.92	0.45	10.1	11.1	1.54	.284	4.90	118	3.90	106	9.36	-3.6
13	Buck Ewing B. Ewing	1,129	4	9	2	3	.400	3.45	23	4	0	0	47.0	55	18	2	23		4	233	3	4.40	4.40	1.00	0.38	9.9	9.9	1.66	.288	6.89	95	4.07	114	10.53	-1.8
14	Fred Pfeffer F. Pfeffer	1,096	2	8	2	1	.667	2.62	13	2	0	2	44.2	41	13	1	20		6	194	4	2.62	4.03	0.65	0.20	6.7	10.3	1.37	.252	5.24	81	4.11	115	8.26	-2.5
15	Tommy McCarthy T. McCarthy	1,066	7	13	0	8	.000	4.99	21	5	0	0	70.1	85	39	3	26		7	323	12	2.69	3.33	0.81	0.38	6.5	8.0	1.58	.300	8.32	157	4.27	148	10.88	-10.7
16	Alvin Dark A. Dark	1,064	1	1	0	0		18.00	0	0	0	0	1.0	1	2	1	1	0	0	5	0	0.00	9.00	0.00	9.00	0.0	20.0	2.00	.000	18.00	420	18.59	437	9.00	-1.6
17	Charlie Jamieson C. Jamieson	1,062	3	13	2	1	.667	6.19	7	1	0	0	48.0	55	33	0	30	2	8	226	2	1.31	5.63	0.23	0.00	3.1	13.3	1.77	.294	7.69	213	4.11	133	10.31	-5.1
18	Bobby Wallace B. Wallace	1,057	48	57	24	22	.522	3.87	120	37	3	1	402.0	469	173	6	156	13	9	1,799	16	2.69	3.49	0.77	0.13	6.7	8.7	1.55	.308	6.00	80	4.35	90	10.50	23.5
19	Kid Gleason K. Gleason	1,022	266	299	138	131	.513	3.79	744	240	10	6	2389.1	2,552	1,007	76	906	78	30	10,617	83	2.80	3.41	0.82	0.29	7.0	8.5	1.45	.281	5.69	97	3.93	99	9.61	28.1
20	Charlie Comiskey C. Comiskey	992	1	4	0	1	.000	0.73	6	1	0	0	12.1	13	1	0	3		2	58	1	4.38	2.19	2.00	0.00	10.3	5.2	1.30	.265	6.57	22	2.69	91	9.49	0.5
21	Ed Konetchy E. Konetchy	972	1	3	1	1	.500	4.32	6	1	0	0	16.2	19	8	0	7	0	1	74	0	3.24	3.78	0.86	0.00	8.1	9.5	1.56	.311	5.40	158	2.88	101	10.26	-0.1
22	Pete Browning P. Browning	954	1	1	0	1	.000	54.00	0	0	0	0	0.1	2	2	0	2		0	5	0	0.00	54.00	0.00	0.00	0.0	40.0	12.00	1.000	81.00	1699	30.27	964	54.00	-1
23	Paul Radford P. Radford	945	4	10	0	4	.000	8.52	13	3	0	0	43.1	85	41	5	17		3	223	3	2.70	3.53	0.76	1.04	5.8	7.6	2.35	.426	14.33	271	5.13	150	17.65	-9.3
24	Elmer Smith E. Smith	913	136	149	75	57	.568	3.35	525	122	9	0	1210.1	1,167	450	20	422		11	5,237	84	3.90	3.14	1.24	0.15	10.0	8.1	1.31	.271	5.31	91	3.42	94	8.68	30.7
25	Tip O'Neill T. O'Neill	879	33	36	16	16	.500	3.39	91	29	0	0	289.0	307	109	8	115		3	1,319	47	2.83	3.58	0.79	0.25	6.9	8.7	1.46	.272	6.98	107	4.23	133	9.56	-33