Shane Bieber struck out the most hitters in a month in 2021, with 68 strikeouts in April 2021.

	NAME	SO	MONTH	G	W	L	W%	GS	ERA	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Shane Bieber S. Bieber	68	April 2021	6	3	2	.600	6	2.76	0	0	0	42.1	28	13	13	5	14	1	0	0	172	3	14.46	2.98	4.86	1.06	39.5	8.1	0.99	.274	2.76	5.95
2	Gerrit Cole G. Cole	62	April 2021	6	4	1	.800	6	1.43	0	0	0	37.2	24	6	7	1	3	1	0	0	140	2	14.81	0.72	20.67	0.24	44.3	2.1	0.72	.315	1.67	5.73
3	Jacob deGrom J. deGrom	59	April 2021	5	2	2	.500	5	0.51	1	1	0	35.0	16	2	5	2	4	0	0	0	123	0	15.17	1.03	14.75	0.51	48.0	3.3	0.57	.241	1.29	4.11
4	Max Scherzer M. Scherzer	57	May 2021	6	3	2	.600	6	1.83	1	0	0	39.1	21	8	8	5	8	2	0	0	144	0	13.04	1.83	7.13	1.14	39.6	5.6	0.74	.222	1.83	4.81
5	Zack Wheeler Z. Wheeler	57	May 2021	6	2	0	1.000	6	2.08	1	1	0	43.1	30	10	11	2	5	2	0	0	164	2	11.84	1.04	11.40	0.42	34.8	3.0	0.81	.286	2.28	6.23
6	Tyler Glasnow T. Glasnow	56	April 2021	6	3	1	.750	6	1.67	0	0	0	37.2	19	7	7	2	11	0	0	0	143	4	13.38	2.63	5.09	0.48	39.2	7.7	0.80	.230	1.67	4.54
7	Blake Snell B. Snell	54	August 2021	6	3	1	.750	6	1.72	0	0	0	36.2	19	7	7	4	12	0	0	0	139	1	13.25	2.95	4.50	0.98	38.8	8.6	0.85	.217	1.72	4.66
8	Robbie Ray R. Ray	53	June 2021	6	4	1	.800	6	2.86	0	0	0	34.2	30	11	11	5	9	0	0	0	142	0	13.76	2.34	5.89	1.30	37.3	6.3	1.13	.333	2.86	7.79
9	Robbie Ray R. Ray	52	August 2021	6	1	0	1.000	6	1.76	0	0	0	41.0	27	8	8	2	8	1	0	0	154	1	11.41	1.76	6.50	0.44	33.8	5.2	0.85	.275	1.76	5.93
10	Trevor Bauer T. Bauer	51	April 2021	6	3	1	.750	6	2.48	1	0	0	40.0	19	11	12	7	8	2	0	0	148	1	11.48	1.80	6.38	1.58	34.5	5.4	0.68	.150	2.70	4.27
11	Dylan Cease D. Cease	50	August 2021	6	4	0	1.000	6	2.83	0	0	0	35.0	22	11	11	5	12	1	0	0	139	3	12.86	3.09	4.17	1.29	36.0	8.6	0.97	.239	2.83	5.66
12	Kevin Gausman K. Gausman	49	May 2021	6	5	0	1.000	6	0.73	0	0	0	37.0	22	3	3	1	6	0	0	0	139	1	11.92	1.46	8.17	0.24	35.3	4.3	0.76	.253	0.73	5.35
13	Brandon Woodruff B. Woodruff	49	May 2021	6	2	2	.500	6	1.07	0	0	0	42.0	20	5	6	3	8	2	0	0	153	1	10.50	1.71	6.13	0.64	32.0	5.2	0.67	.187	1.29	4.29
14	Corbin Burnes C. Burnes	49	April 2021	5	2	2	.500	5	1.53	0	0	0	29.1	16	5	6	1	0	3	0	0	108	0	15.03	0.00		0.31	45.4	0.0	0.55	.273	1.84	4.91
15	Yu Darvish Y. Darvish	49	April 2021	6	3	1	.750	6	2.13	0	0	0	38.0	23	9	9	4	11	4	0	0	149	2	11.61	2.61	4.45	0.95	32.9	7.4	0.89	.235	2.13	5.45
16	Max Scherzer M. Scherzer	48	September 2021	6	3	0	1.000	6	2.29	0	0	0	39.1	29	10	12	3	3	0	0	0	150	1	10.98	0.69	16.00	0.69	32.0	2.0	0.81	.271	2.75	6.64
17	Sandy Alcantara S. Alcantara	48	August 2021	6	2	3	.400	6	3.18	0	0	0	39.2	31	14	14	5	9	2	0	0	159	1	10.89	2.04	5.33	1.13	30.2	5.7	1.01	.274	3.18	7.03
18	Gerrit Cole G. Cole	47	July 2021	5	2	2	.500	5	4.71	2	1	0	28.2	26	15	16	3	11	0	0	0	123	0	14.76	3.45	4.27	0.94	38.2	8.9	1.29	.371	5.02	8.16
19	Clayton Kershaw C. Kershaw	47	June 2021	5	2	3	.400	5	3.09	0	0	0	32.0	27	11	12	4	5	1	0	0	129	2	13.22	1.41	9.40	1.13	36.4	3.9	1.00	.319	3.38	7.59
20	Robbie Ray R. Ray	46	September 2021	6	3	2	.600	6	3.44	0	0	0	34.0	27	13	13	8	14	1	0	0	140	1	12.18	3.71	3.29	2.12	32.9	10.0	1.21	.268	3.44	7.15
21	Kevin Gausman K. Gausman	46	September 2021	6	2	1	.667	6	4.64	0	0	0	33.0	37	17	17	7	3	0	0	0	138	0	12.55	0.82	15.33	1.91	33.3	2.2	1.21	.366	4.64	10.09
22	Charlie Morton C. Morton	46	August 2021	6	2	2	.500	6	2.83	0	0	0	35.0	24	11	11	4	7	1	0	0	134	0	11.83	1.80	6.57	1.03	34.3	5.2	0.89	.263	2.83	6.17
23	Trevor Bauer T. Bauer	45	May 2021	6	3	2	.600	6	1.98	0	0	0	36.1	21	8	10	6	15	1	0	0	146	2	11.15	3.72	3.00	1.49	30.8	10.3	0.99	.190	2.48	5.20
24	Lucas Giolito L. Giolito	45	May 2021	6	4	2	.667	6	2.41	0	0	0	37.1	25	10	12	5	14	0	0	0	149	3	10.85	3.38	3.21	1.21	30.2	9.4	1.04	.235	2.89	6.03
25	Freddy Peralta F. Peralta	45	April 2021	6	3	0	1.000	5	2.25	0	0	0	28.0	14	7	7	3	14	2	0	0	112	2	14.46	4.50	3.21	0.96	40.2	12.5	1.00	.229	2.25	4.50