Sammy Sosa and Jim Thome were tied for the most strikeouts in 1999, with 171 strikeouts.

	NAME	SO	SEASON	TM	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Sammy Sosa S. Sosa	171	1999	CHC	162	625	114	180	24	2	63	141	78	3	7	8	712	397	89	0	6	8	17	.288	.367	.635	1.002	138	45.2	.414	143	41.3
2	Jim Thome J. Thome	171	1999	CLE	146	494	101	137	27	2	33	108	127	4	0	0	629	267	62	0	4	13	6	.277	.426	.540	.967	121	39.5	.413	142	35.6
3	Preston Wilson P. Wilson	156	1999	FLA	149	482	67	135	21	4	26	71	46	9	11	4	543	242	51	0	6	3	15	.280	.350	.502	.852	82	11.4	.365	115	11.3
4	Dean Palmer D. Palmer	153	1999	DET	150	560	92	147	25	2	38	100	57	10	3	3	631	290	65	0	4	3	12	.263	.339	.518	.857	96	13.4	.365	112	10.3
5	Mike Cameron M. Cameron	145	1999	CIN	146	542	93	139	34	9	21	66	80	6	38	12	636	254	64	5	3	2	4	.256	.357	.469	.825	93	10.4	.360	107	6.1
6	Jose Hernandez J. Hernandez	145	1999	TOT	147	508	79	135	20	2	19	62	52	5	11	3	568	216	41	2	1	6	10	.266	.339	.425	.764	71	-3.3	.334	92	-6.1
7	Troy Glaus T. Glaus	143	1999	ANA	154	551	85	132	29	0	29	79	71	6	5	1	631	248	58	0	3	1	9	.240	.331	.450	.781	82	0.2	.341	96	-3.6
8	Ruben Rivera R. Rivera	143	1999	SDP	147	411	65	80	16	1	23	48	55	5	18	7	475	167	40	0	4	1	9	.195	.295	.406	.701	48	-13.9	.307	81	-12.1
9	Carlos Delgado C. Delgado	141	1999	TOR	152	573	113	156	39	0	44	134	86	15	1	1	681	327	83	0	7	7	11	.272	.377	.571	.948	123	34.5	.399	134	31.3
10	Mark McGwire M. McGwire	141	1999	STL	153	521	118	145	21	1	65	147	133	2	0	0	661	363	87	0	5	21	12	.278	.424	.697	1.120	150	64.2	.453	169	61.5
11	Greg Vaughn G. Vaughn	137	1999	CIN	153	550	104	135	20	2	45	118	85	3	15	2	643	294	67	0	5	3	9	.245	.347	.535	.881	102	18.3	.374	116	14
12	Jose Canseco J. Canseco	135	1999	TBD	113	430	75	120	18	1	34	95	58	7	3	0	502	242	53	0	7	3	14	.279	.369	.563	.931	88	22.7	.393	130	20.3
13	Raul Mondesi R. Mondesi	134	1999	LAD	159	601	98	152	29	5	33	99	71	3	36	9	680	290	67	0	5	6	3	.253	.332	.483	.815	93	4.3	.348	107	6.9
14	Tony Clark T. Clark	133	1999	DET	143	536	74	150	29	0	31	99	64	6	2	1	609	272	60	0	3	7	14	.280	.361	.507	.869	96	16.4	.372	117	13.5
15	Jay Bell J. Bell	132	1999	ARI	151	589	132	170	32	6	38	112	82	4	7	4	688	328	76	4	9	2	9	.289	.374	.557	.931	122	32.3	.395	129	26.8
16	Rico Brogna R. Brogna	132	1999	PHI	157	619	90	172	29	4	24	102	54	2	8	5	679	281	57	0	4	7	19	.278	.336	.454	.790	88	-0.2	.340	95	-4.8
17	Lee Stevens L. Stevens	132	1999	TEX	146	517	76	146	31	1	24	81	52	0	2	3	576	251	56	0	7	10	19	.282	.344	.485	.829	80	5.3	.351	101	1
18	Manny Ramirez M. Ramirez	131	1999	CLE	147	522	131	174	34	3	44	165	96	13	2	4	640	346	81	0	9	9	12	.333	.442	.663	1.105	149	65.7	.459	172	61.8
19	Derek Bell D. Bell	129	1999	HOU	128	509	61	120	22	0	12	66	50	4	18	6	568	178	34	0	5	1	20	.236	.306	.350	.656	51	-22.7	.294	72	-21.3
20	John Jaha J. Jaha	129	1999	OAK	142	457	93	126	23	0	35	111	101	9	2	0	570	254	58	0	3	2	14	.276	.414	.556	.970	112	37.7	.417	149	37.2
21	Fernando Tatis F. Tatis	128	1999	STL	149	537	104	160	31	2	34	107	82	16	21	9	639	297	67	0	4	4	11	.298	.404	.553	.957	122	38.7	.411	142	36
22	Jeff Bagwell J. Bagwell	127	1999	HOU	162	562	143	171	35	0	42	126	149	11	30	11	729	332	77	0	7	16	18	.304	.454	.591	1.045	159	63.9	.442	166	65.7
23	Mo Vaughn M. Vaughn	127	1999	ANA	139	524	63	147	20	0	33	108	54	11	0	0	592	266	53	0	3	7	11	.281	.358	.508	.866	92	15.2	.370	115	11.6
24	Jeromy Burnitz J. Burnitz	124	1999	MIL	130	467	87	126	33	2	33	103	91	16	7	3	580	262	68	0	6	7	11	.270	.402	.561	.963	110	34	.408	139	30.9
25	Damion Easley D. Easley	124	1999	DET	151	549	83	146	30	1	20	65	51	19	11	3	627	238	51	2	6	2	15	.266	.346	.434	.779	83	1.2	.343	98	-1.8