Carl Weilman has the most strikeouts by a pitcher in a game, with 6 strikeouts versus the Washington Senators on July 25, 1913.
Interpreted as:
most strike out by a player pitched in one regular-season game all-time| NAME | SO | DATE | TM | OPP | AB | R | H | 2B | 3B | HR | RBI | BB | HBP | SB | CS | PA | TB | XBH | SH | SF | IBB | GIDP | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | C. Weilman | 6 | 7/25/1913 |  SLA | @ |  WSH | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | |||||
| 2 |  | G. Cole | 5 | 5/4/2018 |  HOU | @ |  ARI | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 3 | | T. Lilly | 5 | 6/30/2008 |  CHC | @ |  SFG | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 4 | | C. Hensley | 5 | 5/14/2006 |  SDP | @ | CHC | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 5 | | B. Blyleven | 5 | 7/27/1979 |  PIT | @ |  MON | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 6 | | R. Jarvis | 5 | 4/20/1969 |  BOS | vs |  CLE | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 7 | | S. Bahnsen | 5 | 6/17/1968 |  NYY | @ |  CAL | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 8 | | B. Sadowski | 5 | 4/20/1964 |  MIL | @ |  LAD | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 9 | | R. Kline | 5 | 9/22/1958 | PIT | @ |  PHI | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 10 | | J. Broaca | 5 | 6/25/1934 | NYY | vs |  CWS | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | |||
| 11 | | L. Grove | 5 | 6/10/1933 |  PHA | vs | NYY | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | |||
| 12 | | S. Perry | 5 | 4/28/1919 | PHA | @ | NYY | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | ||||
| 13 | | L. Williams | 5 | 5/15/1918 | CWS | @ | WSH | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | ||||
| 14 | | C. Morgan | 5 | 9/18/1911 | PHA | vs | CWS | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | ||||
| 15 | | B. Harmon | 5 | 7/7/1911 |  SLN | @ | PHN | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | |||
| 16 | | S. Sallee | 5 | 7/21/1908 | SLN | vs |  NYG | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | ||||
| 17 | | G. Winter | 5 | 9/5/1905 |  BSA | vs | PHA | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | ||||
| 18 | | B. Bernhard | 5 | 8/11/1904 |  CLE | vs | PHA | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | ||||
| 19 | | C. Hernández | 4 | 8/22/2021 |  KCR | @ | CHC | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 20 | | E. Lauer | 4 | 7/3/2021 |  MIL | @ | PIT | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 21 | | T. Rogers | 4 | 6/10/2021 |  MIA | vs |  COL | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 22 |  | T. Anderson | 4 | 5/9/2021 | PIT | @ | CHC | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 23 | | T. Beede | 4 | 7/2/2019 | SFG | @ |  SDP | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 24 | | J. Quintana | 4 | 9/24/2017 | CHC | @ |  MIL | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 25 | | M. Pérez | 4 | 8/9/2017 |  TEX | @ |  NYM | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 |
Results may be incomplete. StatMuse has complete game-level data for strikeouts going back to the 1916 season.
Some of the information used here was obtained free of charge from Retrosheet.
Blue Jays
Red Sox
Rays
Orioles
MIN
Padres
Guardians
Tigers
Mariners
CIN
STL
ATL
WSH
ATH
LAA
