Between the 1860 and 1992 seasons, Reggie Jackson had the most strikeouts, with 2,597 strikeouts.

Interpreted as:

most strikeouts by a player 1860 to 1992

	NAME	SO	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	wRC	WRAA	wOBA	wRC+	BRAA
1	Reggie Jackson R. Jackson	2,597	2,820	9,864	1,551	2,584	463	49	563	1,702	1,375	96	228	115	11,416	4,834	1,075	13	68	164	183	.262	.356	.490	.846	1749	503	.374	139	497.6
2	Willie Stargell W. Stargell	1,936	2,360	7,927	1,194	2,232	423	55	475	1,540	937	78	17	16	9,026	4,190	953	9	75	227	143	.282	.360	.529	.889	1471	511.5	.387	145	459.3
3	Mike Schmidt M. Schmidt	1,883	2,404	8,352	1,506	2,234	408	59	548	1,595	1,507	79	174	92	10,062	4,404	1,015	16	108	201	156	.267	.380	.527	.908	1717	591	.395	147	539.8
4	Tony Perez T. Perez	1,867	2,777	9,778	1,272	2,732	505	79	379	1,652	925	43	49	33	10,861	4,532	963	9	106	150	268	.279	.341	.463	.804	1511	343.8	.356	121	265.2
5	Dave Kingman D. Kingman	1,816	1,941	6,677	901	1,575	240	25	442	1,210	608	53	85	49	7,429	3,191	707	16	75	72	139	.236	.302	.478	.780	960	139.8	.343	113	108.5
6	Bobby Bonds B. Bonds	1,757	1,849	7,043	1,258	1,886	302	66	332	1,024	914	53	461	169	8,090	3,316	700	16	64	75	107	.268	.353	.471	.824	1192	318.7	.368	130	274.9
7	Dale Murphy D. Murphy	1,733	2,154	7,918	1,196	2,105	349	39	398	1,259	981	28	161	68	8,991	3,726	786	6	58	158	204	.266	.347	.471	.817	1291	279.4	.358	120	209.2
8	Lou Brock L. Brock	1,730	2,616	10,332	1,610	3,023	486	141	149	900	761	49	938	307	11,235	4,238	776	47	46	124	114	.293	.343	.410	.753	1406	210.2	.336	109	113.1
9	Mickey Mantle M. Mantle	1,710	2,401	8,102	1,676	2,415	344	72	536	1,509	1,733	13	153	38	9,909	4,511	952	14	47	126	113	.298	.421	.557	.977	1941	840	.428	170	821.8
10	Harmon Killebrew H. Killebrew	1,699	2,435	8,147	1,283	2,086	290	24	573	1,584	1,559	48	19	18	9,831	4,143	887	0	77	160	243	.256	.376	.509	.884	1630	569	.389	142	477.8
11	Dwight Evans D. Evans	1,697	2,606	8,996	1,470	2,446	483	73	385	1,384	1,391	53	78	59	10,569	4,230	941	52	77	60	227	.272	.370	.470	.840	1640	459.6	.375	129	357.7
12	Lee May L. May	1,570	2,071	7,609	959	2,031	340	31	354	1,244	487	49	39	35	8,219	3,495	725	9	65	85	219	.267	.313	.459	.772	1053	174.1	.343	116	143.5
13	Dick Allen D. Allen	1,556	1,749	6,332	1,099	1,848	320	79	351	1,119	894	16	133	52	7,314	3,379	750	19	53	138	164	.292	.378	.534	.912	1258	491.7	.400	155	443.3
14	Willie McCovey W. McCovey	1,550	2,588	8,197	1,229	2,211	353	46	521	1,555	1,345	69	26	22	9,686	4,219	920	5	70	260	176	.270	.374	.515	.889	1594	551.5	.388	145	497.9
15	Dave Parker D. Parker	1,537	2,466	9,358	1,272	2,712	526	75	339	1,493	683	56	154	113	10,184	4,405	940	1	86	170	209	.290	.339	.471	.810	1419	274.5	.354	120	232.3
16	Frank Robinson F. Robinson	1,532	2,808	10,006	1,829	2,943	528	72	586	1,812	1,420	198	204	77	11,743	5,373	1,186	17	102	218	270	.294	.389	.537	.926	2083	807.2	.404	153	717.1
17	Willie Mays W. Mays	1,526	2,992	10,881	2,062	3,283	523	140	660	1,903	1,464	44	338	103	12,493	6,066	1,323	13	91	192	251	.302	.384	.557	.941	2266	894.8	.409	154	802.7
18	Rick Monday R. Monday	1,513	1,986	6,136	950	1,619	248	64	241	775	924	24	98	91	7,162	2,718	553	46	32	107	71	.264	.361	.443	.804	1014	251.3	.361	125	199.9
19	Dave Winfield D. Winfield	1,503	2,707	10,047	1,551	2,866	493	83	432	1,710	1,126	24	218	92	11,306	4,821	1,008	18	91	163	292	.285	.356	.480	.836	1688	421.7	.367	132	413.3
20	Greg Luzinski G. Luzinski	1,495	1,821	6,505	880	1,795	344	24	307	1,128	845	84	37	31	7,514	3,108	675	1	79	95	147	.276	.363	.478	.840	1141	317.2	.373	131	262.9
21	Eddie Mathews E. Mathews	1,487	2,391	8,537	1,509	2,315	354	72	512	1,453	1,444	26	68	39	10,101	4,349	938	36	58	107	123	.271	.376	.509	.885	1685	557.5	.389	143	531.2
22	Frank Howard F. Howard	1,460	1,895	6,488	864	1,774	245	35	382	1,119	782	33	8	9	7,353	3,235	662	7	43	135	219	.273	.352	.499	.851	1134	353.9	.374	140	326.1
23	Lance Parrish L. Parrish	1,442	1,868	6,743	829	1,708	290	27	316	1,030	575	35	26	36	7,424	3,000	633	16	55	61	186	.253	.313	.445	.758	926	91.2	.334	107	59.6
24	Jack Clark J. Clark	1,441	1,994	6,847	1,118	1,826	332	39	340	1,180	1,262	24	77	61	8,225	3,256	711	9	83	127	174	.267	.379	.476	.854	1297	373.2	.377	138	359.8
25	Jimmy Wynn J. Wynn	1,427	1,920	6,653	1,105	1,665	285	39	291	964	1,224	27	225	101	8,010	2,901	615	32	74	84	117	.250	.366	.436	.802	1148	306.9	.362	130	264.7

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StatMuse has season-level data for strikeouts going back to the 1891 season.

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Fri 3/27	ATH	@	TOR	7:07 PM
Sat 3/28	ATH	@	TOR	3:07 PM
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Tue 9/16	TOR	@	TBR	1-2
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Wed 3/25	NYY	@	SFG	8:05 PM
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Between the 1860 and 1992 seasons, Reggie Jackson had the most strikeouts, with 2,597 strikeouts.

Interpreted as:

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