
| NAME | SO | G | W | L | W% | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | ERA- | FIP | FIP- | H/9 | PRAA | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | J. Lester | 1,386 | 242 | 110 | 63 | .636 | 241 | 3.64 | 10 | 3 | 0 | 1519.1 | 1,426 | 615 | 655 | 138 | 529 | 55 | 0 | 4 | 6,378 | 38 | 8.21 | 3.13 | 2.62 | 0.82 | 21.7 | 8.3 | 1.29 | .302 | 3.88 | 84 | 3.60 | 88 | 8.45 | 81.9 | |
| 2 | T. Wakefield | 1,386 | 411 | 121 | 113 | .517 | 292 | 4.46 | 8 | 0 | 7 | 2041.2 | 1,980 | 1,011 | 1,130 | 268 | 699 | 120 | 46 | 22 | 8,764 | 97 | 6.11 | 3.08 | 1.98 | 1.18 | 15.8 | 8.0 | 1.31 | .272 | 4.98 | 97 | 4.62 | 108 | 8.73 | -80 | |
| 3 | P. Martinez | 1,119 | 139 | 75 | 26 | .743 | 139 | 2.53 | 14 | 5 | 0 | 936.2 | 696 | 263 | 290 | 68 | 205 | 60 | 0 | 1 | 3,712 | 15 | 10.75 | 1.97 | 5.46 | 0.65 | 30.1 | 5.5 | 0.96 | .278 | 2.79 | 54 | 2.44 | 56 | 6.69 | 208.3 | |
| 4 | J. Beckett | 1,108 | 194 | 89 | 58 | .605 | 194 | 4.17 | 7 | 3 | 0 | 1240.0 | 1,179 | 574 | 604 | 153 | 338 | 53 | 0 | 9 | 5,190 | 35 | 8.04 | 2.45 | 3.28 | 1.11 | 21.3 | 6.5 | 1.22 | .290 | 4.38 | 93 | 3.87 | 92 | 8.56 | 46.7 | |
| 5 | C. Sale | 945 | 115 | 46 | 30 | .605 | 115 | 3.27 | 2 | 1 | 0 | 670.2 | 527 | 244 | 266 | 80 | 156 | 48 | 0 | 1 | 2,713 | 12 | 12.68 | 2.09 | 6.06 | 1.07 | 34.8 | 5.8 | 1.02 | .301 | 3.57 | 71 | 2.82 | 65 | 7.07 | 113.5 | |
| 6 | C. Buchholz | 899 | 206 | 81 | 61 | .570 | 188 | 3.96 | 9 | 6 | 0 | 1167.2 | 1,104 | 514 | 565 | 116 | 417 | 45 | 7 | 9 | 4,920 | 28 | 6.93 | 3.21 | 2.16 | 0.89 | 18.3 | 8.5 | 1.30 | .287 | 4.35 | 93 | 4.04 | 100 | 8.51 | -0.4 | |
| 7 | E. Rodriguez | 892 | 159 | 64 | 39 | .621 | 153 | 4.16 | 0 | 0 | 0 | 856.2 | 831 | 396 | 410 | 107 | 294 | 25 | 1 | 6 | 3,649 | 9 | 9.37 | 3.09 | 3.03 | 1.12 | 24.4 | 8.1 | 1.31 | .311 | 4.31 | 92 | 3.82 | 89 | 8.73 | 44 | |
| 8 | R. Porcello | 852 | 159 | 73 | 55 | .570 | 159 | 4.43 | 6 | 0 | 0 | 964.0 | 1,000 | 475 | 524 | 144 | 211 | 51 | 0 | 3 | 4,088 | 28 | 7.95 | 1.97 | 4.04 | 1.34 | 20.8 | 5.2 | 1.26 | .302 | 4.89 | 99 | 4.14 | 98 | 9.34 | 10 | |
| 9 | N. Pivetta | 718 | 131 | 37 | 41 | .474 | 107 | 4.29 | 1 | 0 | 2 | 633.0 | 558 | 302 | 312 | 103 | 229 | 17 | 4 | 4 | 2,658 | 28 | 10.21 | 3.26 | 3.14 | 1.46 | 27.0 | 8.6 | 1.24 | .286 | 4.44 | 99 | 4.18 | 100 | 7.93 | 0.4 | |
| 10 | D. Price | 609 | 103 | 46 | 24 | .657 | 98 | 3.84 | 3 | 0 | 0 | 588.0 | 552 | 251 | 268 | 78 | 156 | 24 | 1 | 1 | 2,448 | 10 | 9.32 | 2.39 | 3.90 | 1.19 | 24.9 | 6.4 | 1.20 | .300 | 4.10 | 85 | 3.73 | 87 | 8.45 | 35.6 | |
| 11 | D. Matsuzaka | 609 | 117 | 50 | 37 | .575 | 116 | 4.52 | 1 | 0 | 0 | 668.1 | 627 | 336 | 347 | 75 | 321 | 34 | 1 | 4 | 2,919 | 25 | 8.20 | 4.32 | 1.90 | 1.01 | 20.9 | 11.0 | 1.42 | .294 | 4.67 | 101 | 4.36 | 104 | 8.44 | -13.1 | |
| 12 | C. Schilling | 574 | 119 | 53 | 29 | .646 | 98 | 3.95 | 4 | 1 | 9 | 675.0 | 712 | 296 | 301 | 84 | 108 | 13 | 21 | 2 | 2,795 | 5 | 7.65 | 1.44 | 5.31 | 1.12 | 20.5 | 3.9 | 1.21 | .312 | 4.01 | 85 | 3.56 | 82 | 9.49 | 60.3 | |
| 13 | M. Barnes | 556 | 429 | 32 | 30 | .516 | 2 | 4.07 | 0 | 0 | 47 | 431.2 | 379 | 195 | 209 | 50 | 200 | 17 | 134 | 8 | 1,862 | 43 | 11.59 | 4.17 | 2.78 | 1.04 | 29.9 | 10.7 | 1.34 | .317 | 4.36 | 91 | 3.59 | 85 | 7.90 | 31.2 | |
| 14 | J. Lackey | 541 | 111 | 47 | 43 | .522 | 111 | 4.46 | 3 | 0 | 0 | 701.2 | 752 | 348 | 373 | 79 | 200 | 34 | 0 | 3 | 3,023 | 21 | 6.94 | 2.57 | 2.71 | 1.01 | 17.9 | 6.6 | 1.36 | .310 | 4.78 | 106 | 3.98 | 101 | 9.65 | -3.5 | |
| 15 | J. Papelbon | 509 | 396 | 23 | 19 | .548 | 3 | 2.33 | 0 | 0 | 219 | 429.1 | 322 | 111 | 126 | 31 | 115 | 17 | 334 | 10 | 1,729 | 10 | 10.67 | 2.41 | 4.43 | 0.65 | 29.4 | 6.7 | 1.02 | .275 | 2.64 | 52 | 2.59 | 61 | 6.75 | 79.2 | |
| 16 | D. Lowe | 503 | 239 | 61 | 41 | .598 | 101 | 3.83 | 2 | 1 | 66 | 788.2 | 799 | 336 | 382 | 57 | 242 | 38 | 114 | 20 | 3,362 | 17 | 5.74 | 2.76 | 2.08 | 0.65 | 15.0 | 7.2 | 1.32 | .294 | 4.36 | 82 | 3.75 | 86 | 9.12 | 53.7 | |
| 17 | N. Eovaldi | 468 | 96 | 26 | 18 | .591 | 84 | 4.05 | 2 | 1 | 0 | 461.2 | 477 | 208 | 230 | 63 | 109 | 17 | 2 | 2 | 1,956 | 19 | 9.12 | 2.12 | 4.29 | 1.23 | 23.9 | 5.6 | 1.27 | .319 | 4.48 | 90 | 3.72 | 87 | 9.30 | 27.6 | |
| 18 | B. Bello | 464 | 100 | 39 | 36 | .520 | 97 | 4.09 | 2 | 0 | 0 | 543.1 | 544 | 247 | 266 | 60 | 195 | 32 | 0 | 1 | 2,338 | 14 | 7.69 | 3.23 | 2.38 | 0.99 | 19.8 | 8.3 | 1.36 | .305 | 4.41 | 94 | 4.15 | 99 | 9.01 | 2.8 | |
| 19 | T. Houck | 449 | 113 | 24 | 32 | .429 | 80 | 3.97 | 1 | 1 | 9 | 474.1 | 429 | 209 | 233 | 43 | 158 | 40 | 16 | 5 | 2,004 | 12 | 8.52 | 3.00 | 2.84 | 0.82 | 22.4 | 7.9 | 1.24 | .294 | 4.42 | 91 | 3.71 | 88 | 8.14 | 25.8 | |
| 20 | K. Crawford | 389 | 86 | 17 | 31 | .354 | 69 | 4.56 | 0 | 0 | 0 | 392.1 | 348 | 199 | 210 | 64 | 118 | 16 | 8 | 1 | 1,633 | 12 | 8.92 | 2.71 | 3.30 | 1.47 | 23.8 | 7.2 | 1.19 | .272 | 4.82 | 106 | 4.34 | 105 | 7.98 | -7.5 | |
| 21 | F. Doubront | 378 | 98 | 26 | 22 | .542 | 69 | 4.82 | 0 | 0 | 3 | 418.0 | 431 | 224 | 247 | 51 | 186 | 13 | 8 | 0 | 1,851 | 20 | 8.14 | 4.00 | 2.03 | 1.10 | 20.4 | 10.0 | 1.48 | .311 | 5.32 | 115 | 4.28 | 109 | 9.28 | -16.1 | |
| 22 | G. Whitlock | 343 | 165 | 25 | 14 | .641 | 23 | 3.13 | 0 | 0 | 10 | 313.2 | 279 | 109 | 122 | 32 | 76 | 13 | 33 | 4 | 1,281 | 10 | 9.84 | 2.18 | 4.51 | 0.92 | 26.8 | 5.9 | 1.13 | .302 | 3.50 | 72 | 3.15 | 75 | 8.01 | 36.3 | |
| 23 | J. Kelly | 319 | 182 | 26 | 11 | .703 | 41 | 4.33 | 0 | 0 | 2 | 359.1 | 335 | 173 | 181 | 32 | 164 | 18 | 29 | 1 | 1,557 | 17 | 7.99 | 4.11 | 1.95 | 0.80 | 20.5 | 10.5 | 1.39 | .296 | 4.53 | 102 | 4.04 | 100 | 8.39 | 0.3 | |
| 24 | B. Workman | 317 | 214 | 25 | 16 | .610 | 18 | 3.83 | 0 | 0 | 20 | 308.0 | 264 | 131 | 144 | 32 | 141 | 4 | 62 | 9 | 1,297 | 8 | 9.26 | 4.12 | 2.25 | 0.94 | 24.4 | 10.9 | 1.31 | .289 | 4.21 | 89 | 3.85 | 94 | 7.71 | 9.8 | |
| 25 | D. Pomeranz | 311 | 72 | 22 | 17 | .564 | 56 | 4.24 | 0 | 0 | 0 | 316.1 | 323 | 149 | 157 | 45 | 137 | 8 | 6 | 2 | 1,376 | 13 | 8.85 | 3.90 | 2.27 | 1.28 | 22.6 | 10.0 | 1.45 | .318 | 4.47 | 94 | 4.41 | 103 | 9.19 | -4.8 | |