Between October 15, 2020 and October 15, 2025, Lance Lynn and Spencer Strider are tied for striking out the most hitters in a game, with 16 strikeouts.
Interpreted as:
most strikeouts by a pitcher in a regular-season game last 5 years| NAME | SO | DATE | TM | OPP | DEC | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | L. Lynn | 16 | 6/18/2023 |  CWS | @ |  SEA | L | 1 | 3.86 | 0 | 0 | 0 | 7.0 | 4 | 3 | 3 | 0 | 2 | 0 | 0 | 0 | 27 | 0 |
| 2 |  | S. Strider | 16 | 9/1/2022 |  ATL | vs |  COL | W | 1 | 0.00 | 0 | 0 | 0 | 8.0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 27 | 0 |
| 3 | | G. Holmes | 15 | 6/15/2025 | ATL | vs | COL | L | 1 | 2.84 | 0 | 0 | 0 | 6.1 | 3 | 2 | 3 | 1 | 2 | 1 | 0 | 0 | 24 | 0 |
| 4 |  | B. Snell | 15 | 7/27/2024 |  SFG | vs | COL | 1 | 0.00 | 0 | 0 | 0 | 6.0 | 2 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 22 | 1 | |
| 5 |  | G. Cole | 15 | 9/1/2021 |  NYY | @ |  LAA | W | 1 | 1.29 | 0 | 0 | 0 | 7.0 | 4 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 25 | 0 |
| 6 |  | C. Burnes | 15 | 8/11/2021 |  MIL | @ |  CHC | W | 1 | 0.00 | 0 | 0 | 0 | 8.0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 27 | 0 |
| 7 |  | J. deGrom | 15 | 4/23/2021 |  NYM | vs |  WSH | W | 1 | 0.00 | 1 | 1 | 0 | 9.0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 29 | 0 |
| 8 | | G. Kirby | 14 | 9/14/2025 | SEA | vs | LAA | W | 1 | 2.84 | 0 | 0 | 0 | 6.1 | 3 | 2 | 2 | 2 | 0 | 0 | 0 | 0 | 22 | 0 |
| 9 | | G. Kirby | 14 | 6/8/2025 | SEA | @ | LAA | W | 1 | 2.57 | 0 | 0 | 0 | 7.0 | 2 | 2 | 2 | 1 | 0 | 0 | 0 | 0 | 23 | 0 |
| 10 | | M. Meyer | 14 | 4/21/2025 |  MIA | vs |  CIN | W | 1 | 0.00 | 0 | 0 | 0 | 6.0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 23 | 0 |
| 11 |  | P. López | 14 | 6/23/2024 |  MIN | @ |  OAK | W | 1 | 0.00 | 0 | 0 | 0 | 8.0 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 27 | 0 |
| 12 |  | L. Gil | 14 | 5/18/2024 | NYY | vs | CWS | W | 1 | 1.50 | 0 | 0 | 0 | 6.0 | 5 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 24 | 0 |
| 13 |  | J. Flaherty | 14 | 4/30/2024 |  DET | vs |  STL | 1 | 0.00 | 0 | 0 | 0 | 6.2 | 2 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 23 | 0 | |
| 14 | | T. Glasnow | 14 | 4/9/2024 |  LAD | @ | MIN | W | 1 | 0.00 | 0 | 0 | 0 | 7.0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 24 | 0 |
| 15 |  | H. Greene | 14 | 9/20/2023 | CIN | vs | MIN | 1 | 1.29 | 0 | 0 | 0 | 7.0 | 3 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 25 | 0 | |
| 16 | | P. López | 14 | 9/10/2023 | MIN | vs | NYM | 1 | 0.00 | 0 | 0 | 0 | 8.0 | 2 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 28 | 0 | |
| 17 | | T. Glasnow | 14 | 9/6/2023 |  TBR | vs |  BOS | W | 1 | 1.50 | 0 | 0 | 0 | 6.0 | 3 | 1 | 1 | 0 | 1 | 0 | 0 | 0 | 22 | 0 |
| 18 | | C. Burnes | 14 | 9/8/2022 | MIL | vs | SFG | W | 1 | 1.13 | 0 | 0 | 0 | 8.0 | 3 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 27 | 0 |
| 19 | | G. Cole | 14 | 9/7/2022 | NYY | vs | MIN | W | 1 | 1.35 | 0 | 0 | 0 | 6.2 | 5 | 1 | 1 | 1 | 2 | 0 | 0 | 0 | 27 | 0 |
| 20 | | T. McKenzie | 14 | 8/19/2022 |  CLE | vs | CWS | W | 1 | 2.57 | 0 | 0 | 0 | 7.0 | 6 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 26 | 1 |
| 21 | | C. Javier | 14 | 7/1/2022 |  HOU | vs | LAA | W | 1 | 1.29 | 0 | 0 | 0 | 7.0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 22 | 0 |
| 22 |  | S. Alcantara | 14 | 5/28/2022 | MIA | @ | ATL | W | 1 | 1.13 | 0 | 0 | 0 | 8.0 | 4 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 26 | 0 |
| 23 | | C. Burnes | 14 | 9/11/2021 | MIL | @ |  CLE | W | 1 | 0.00 | 0 | 0 | 0 | 8.0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 25 | 0 |
| 24 | | S. Alcantara | 14 | 9/8/2021 | MIA | vs | NYM | 1 | 1.00 | 0 | 0 | 0 | 9.0 | 4 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 31 | 0 | |
| 25 |  | R. Ray | 14 | 8/25/2021 |  TOR | vs | CWS | 1 | 1.29 | 0 | 0 | 0 | 7.0 | 5 | 1 | 1 | 0 | 1 | 1 | 0 | 0 | 28 | 0 | |
Some of the information used here was obtained free of charge from Retrosheet.
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