Between the 2010 and 2021 seasons, Justin Upton had the most strikeouts, with 1,653 strikeouts.

Interpreted as:

most strikeouts by a player from 2010 to 2021

	NAME	SO	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Justin Upton J. Upton	1,653	1,539	5,651	903	1,470	292	22	281	861	659	68	128	50	6,432	2,649	595	2	52	36	125	.260	.342	.469	.810	911	169.6	.349	119	143.1
2	Chris Davis C. Davis	1,614	1,224	4,292	608	983	190	2	257	666	511	55	18	9	4,894	1,948	449	1	35	47	51	.229	.317	.454	.770	619	55.2	.330	106	32.1
3	Giancarlo Stanton G. Stanton	1,559	1,324	4,839	762	1,299	265	11	347	893	647	49	42	15	5,568	2,627	623	0	33	81	117	.268	.358	.543	.901	932	289	.380	142	279.1
4	Nelson Cruz N. Cruz	1,486	1,578	5,891	886	1,653	302	10	394	1,080	587	75	53	23	6,606	3,157	706	1	52	67	145	.281	.350	.536	.886	1082	314.3	.374	138	297
5	Paul Goldschmidt P. Goldschmidt	1,404	1,469	5,366	939	1,572	341	22	280	927	837	39	140	33	6,288	2,797	643	0	46	107	127	.293	.389	.521	.911	1089	354.5	.385	141	308.9
6	Ian Desmond I. Desmond	1,388	1,457	5,360	715	1,409	270	35	177	699	382	43	180	56	5,855	2,280	482	32	38	13	130	.263	.315	.425	.740	694	21.9	.321	95	-35.5
7	Jay Bruce J. Bruce	1,387	1,441	5,206	729	1,273	280	29	276	841	529	22	58	31	5,802	2,439	585	2	43	68	88	.245	.314	.468	.783	743	76.3	.332	107	51
8	Mark Reynolds M. Reynolds	1,371	1,270	3,949	547	902	175	6	209	610	530	43	29	19	4,554	1,716	390	1	31	19	94	.228	.324	.435	.759	573	51.3	.330	100	0
9	Andrew McCutchen A. McCutchen	1,335	1,653	6,087	978	1,702	341	40	258	879	872	75	175	73	7,095	2,897	639	3	58	64	105	.280	.374	.476	.849	1104	284.7	.366	132	269.7
10	Freddie Freeman F. Freeman	1,312	1,565	5,767	969	1,704	367	25	271	941	776	76	53	24	6,660	2,934	663	0	41	102	126	.295	.384	.509	.893	1122	346.7	.379	138	312.3
11	Curtis Granderson C. Granderson	1,298	1,383	4,657	782	1,098	221	38	242	638	650	53	86	33	5,410	2,121	501	12	38	23	46	.236	.334	.455	.789	730	108.1	.341	115	95.1
12	Shin-Soo Choo S. Choo	1,291	1,337	4,995	777	1,348	261	17	181	602	723	128	127	46	5,882	2,186	459	9	27	31	84	.270	.374	.438	.812	869	188.7	.356	122	148.6
13	J.D. Martinez	1,279	1,270	4,753	714	1,376	296	20	266	837	466	27	25	11	5,291	2,510	582	0	45	52	147	.290	.353	.528	.881	861	240.8	.371	133	209.5
14	Evan Longoria E. Longoria	1,278	1,544	5,797	794	1,532	334	24	257	891	562	56	42	19	6,492	2,685	615	1	76	70	157	.264	.331	.463	.794	867	116.1	.339	116	121.9
15	Joey Votto J. Votto	1,258	1,594	5,643	952	1,693	358	17	278	880	1,160	58	68	23	6,906	2,919	653	0	45	127	143	.300	.422	.517	.939	1275	471.3	.401	151	419
16	Alex Gordon A. Gordon	1,235	1,419	5,191	707	1,343	280	21	153	608	556	100	85	39	5,887	2,124	454	5	35	39	85	.259	.340	.409	.749	731	51.4	.328	104	23.5
17	Matt Kemp M. Kemp	1,230	1,286	4,707	683	1,313	256	19	226	789	395	22	99	39	5,181	2,285	501	0	57	56	152	.279	.334	.485	.819	728	134.4	.349	122	129
18	Mike Trout M. Trout	1,215	1,288	4,656	967	1,419	268	49	310	816	865	86	203	37	5,659	2,715	627	0	52	109	58	.305	.419	.583	1.002	1134	478.3	.419	172	481.2
19	Dexter Fowler D. Fowler	1,205	1,312	4,581	741	1,187	224	72	123	483	673	49	122	57	5,357	1,924	419	29	25	15	54	.259	.358	.420	.778	728	108.9	.342	109	57.3
20	Bryce Harper B. Harper	1,189	1,283	4,557	850	1,273	270	22	267	752	833	36	111	39	5,482	2,388	559	12	44	103	93	.279	.392	.524	.916	957	313.9	.386	142	279.9
21	Brett Gardner B. Gardner	1,175	1,538	5,362	877	1,374	240	65	136	539	665	62	235	58	6,189	2,152	441	60	40	6	55	.256	.343	.401	.744	774	55.7	.327	105	35
22	Carlos Santana C. Santana	1,158	1,653	5,898	865	1,446	316	16	259	865	1,077	32	48	18	7,061	2,571	591	0	54	60	150	.245	.362	.436	.798	999	177.4	.347	118	151.3
23	Adam Jones A. Jones	1,151	1,499	5,920	797	1,647	287	18	251	806	275	88	72	26	6,335	2,723	556	5	47	17	162	.278	.318	.460	.778	820	91.4	.334	108	59
24	Eric Hosmer E. Hosmer	1,146	1,554	5,875	767	1,629	300	20	188	835	519	22	76	30	6,458	2,533	508	3	39	48	150	.277	.336	.431	.767	829	77.4	.331	107	55.5
25	Mike Napoli M. Napoli	1,142	1,026	3,476	511	844	169	8	201	563	491	47	22	13	4,035	1,632	378	0	21	23	98	.243	.343	.470	.812	572	112.7	.352	118	81.2