Between the 2000 and 2009 seasons, Adam Dunn had the most strikeouts, with 1,433 strikeouts.

Interpreted as:

most strikeouts by a player in 2000s

	NAME	SO	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	wRC	WRAA	wOBA	wRC+	BRAA
1	Adam Dunn A. Dunn	1,433	1,290	4,417	780	1,101	230	8	316	777	913	62	59	20	5,417	2,295	554	2	23	97	65	.249	.383	.520	.903	913	251.7	.384	131	211.4
2	Jim Thome J. Thome	1,431	1,368	4,629	877	1,255	231	8	368	986	973	37	3	9	5,681	2,606	607	0	42	112	81	.271	.399	.563	.962	1057	355	.404	145	321.6
3	Mike Cameron M. Cameron	1,429	1,387	5,074	799	1,282	292	42	221	760	649	67	208	56	5,854	2,321	555	18	46	16	87	.253	.342	.457	.800	806	83.6	.347	112	92
4	Pat Burrell P. Burrell	1,392	1,428	4,947	700	1,257	269	15	265	891	842	28	7	1	5,864	2,351	549	0	47	49	110	.254	.363	.475	.838	880	159.1	.362	117	127.2
5	Alex Rodriguez A. Rodriguez	1,243	1,524	5,732	1,190	1,740	285	16	435	1,243	850	125	179	37	6,768	3,362	736	0	61	82	149	.304	.401	.587	.988	1325	491.3	.416	154	459.7
6	Bobby Abreu B. Abreu	1,221	1,574	5,800	1,061	1,721	408	37	216	993	1,038	26	295	90	6,932	2,851	661	2	66	82	114	.297	.402	.492	.893	1181	327.1	.386	133	295.7
7	Alfonso Soriano A. Soriano	1,184	1,313	5,403	859	1,505	334	24	289	759	338	65	257	70	5,852	2,754	647	8	38	52	64	.279	.326	.510	.836	839	122.9	.354	112	90.1
8	Andruw Jones A. Jones	1,174	1,413	5,219	852	1,340	263	20	308	917	610	69	69	30	5,955	2,567	591	0	57	47	138	.257	.339	.492	.831	858	121.5	.354	112	93.3
9	Derrek Lee D. Lee	1,164	1,448	5,254	854	1,536	339	26	270	841	695	52	94	41	6,048	2,737	635	2	45	67	146	.292	.378	.521	.899	1017	274.1	.383	131	239.9
10	Richie Sexson R. Sexson	1,152	1,179	4,264	647	1,107	229	9	264	792	548	45	10	9	4,885	2,146	502	0	28	31	120	.260	.348	.503	.851	743	139.3	.364	120	126.1
11	Carlos Delgado C. Delgado	1,121	1,368	4,951	863	1,416	326	12	324	1,045	796	126	9	3	5,938	2,738	662	0	65	151	108	.286	.394	.553	.947	1069	335.2	.397	141	309.5
12	Jim Edmonds J. Edmonds	1,111	1,216	3,968	743	1,113	253	13	261	768	700	33	39	26	4,757	2,175	527	7	49	69	71	.280	.389	.548	.937	851	262.2	.395	140	246.3
13	Manny Ramirez M. Ramirez	1,085	1,358	4,931	933	1,562	328	11	348	1,106	828	69	10	9	5,874	2,956	687	0	46	174	148	.317	.419	.599	1.018	1190	466.7	.424	158	433.5
14	Troy Glaus T. Glaus	1,083	1,207	4,282	733	1,108	237	10	274	777	705	36	50	28	5,059	2,187	521	0	36	37	110	.259	.365	.511	.876	816	191.2	.375	127	174
15	Jorge Posada J. Posada	1,056	1,302	4,426	681	1,251	288	7	208	819	707	59	15	15	5,227	2,177	503	0	35	60	137	.283	.386	.492	.878	859	213.6	.378	130	202.2
16	Geoff Jenkins G. Jenkins	1,038	1,130	3,991	585	1,093	248	18	191	623	363	87	26	10	4,476	1,950	457	0	35	66	96	.274	.345	.489	.833	643	88.7	.354	111	63.6
17	Lance Berkman L. Berkman	1,030	1,473	5,169	959	1,553	357	25	309	1,026	968	61	74	39	6,248	2,887	691	1	49	130	110	.300	.413	.559	.972	1192	424.5	.410	148	384.5
18	Jermaine Dye J. Dye	1,025	1,372	5,110	806	1,406	284	16	274	871	503	57	39	16	5,722	2,544	574	1	51	34	142	.275	.344	.498	.841	848	142.6	.359	114	106.2
19	David Ortiz D. Ortiz	1,004	1,340	4,825	831	1,365	357	14	307	1,016	749	24	9	5	5,653	2,671	678	2	53	87	106	.283	.378	.554	.932	992	296.8	.392	136	258.1
20	Derek Jeter D. Jeter	993	1,500	6,122	1,088	1,940	316	27	161	727	612	107	219	47	6,923	2,793	504	58	24	26	161	.317	.387	.456	.844	1091	238.5	.371	125	221.8
21	Torii Hunter T. Hunter	992	1,357	5,093	779	1,404	304	27	226	842	388	52	153	62	5,567	2,440	557	1	33	41	148	.276	.331	.479	.810	763	78.9	.346	109	62.2
22	Jason Varitek J. Varitek	984	1,208	4,060	513	1,045	238	11	148	596	520	53	22	14	4,674	1,749	397	10	31	54	104	.257	.347	.431	.778	608	32.5	.338	100	1.7
23	Brandon Inge B. Inge	975	1,153	3,823	449	901	173	31	123	494	339	59	40	35	4,293	1,505	327	38	34	11	71	.236	.305	.394	.699	443	-81.1	.306	83	-90.4
24	Carlos Pena C. Pena	973	929	3,136	495	776	153	20	202	566	495	47	18	13	3,713	1,575	375	4	31	33	47	.247	.355	.502	.858	571	119.1	.367	126	119.6
25	Jason Giambi J. Giambi	965	1,305	4,257	775	1,171	224	5	303	912	942	138	13	5	5,387	2,314	532	0	50	69	88	.275	.418	.544	.961	1032	367.6	.410	152	358.4

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StatMuse has season-level data for strikeouts going back to the 1891 season.

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DATE	MATCHUP			TIME (ET)
Sat 5/23	STL	@	CIN	1:10 PM
Sat 5/23	STL	@	CIN	7:15 PM
Sun 5/24	STL	@	CIN	1:40 PM
Mon 5/25	CIN	@	NYM	4:10 PM
Tue 5/26	CIN	@	NYM	7:10 PM

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NL East	W	L	PCT	GB
Braves	36	16	.692
Phillies	25	26	.490	10.5
Nationals	25	27	.481	11.0
Marlins	23	29	.442	13.0
Mets	22	29	.431	13.5
NL Central	W	L	PCT	GB
Brewers	30	18	.625
Cardinals	28	21	.571	2.5
Cubs	29	22	.569	2.5
Reds	26	24	.520	5.0
Pirates	26	25	.510	5.5
NL West	W	L	PCT	GB
Dodgers	31	20	.608
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Giants	20	31	.392	11.0
Rockies	20	32	.385	11.5

AL East	W	L	PCT	GB
Rays	34	15	.694
Yankees	30	22	.577	5.5
Blue Jays	24	27	.471	11.0
Red Sox	22	28	.440	12.5
Orioles	22	29	.431	13.0
AL Central	W	L	PCT	GB
Guardians	31	22	.585
White Sox	26	24	.520	3.5
Twins	24	27	.471	6.0
Royals	20	31	.392	10.0
Tigers	20	32	.385	10.5
AL West	W	L	PCT	GB
Athletics	26	25	.510
Mariners	25	27	.481	1.5
Rangers	24	26	.480	1.5
Astros	21	31	.404	5.5
Angels	18	34	.346	8.5