Since 1960, Nolan Ryan has struck out the most hitters by a starting pitcher, with 5,654 strikeouts.
| NAME | SO | G | W | L | W% | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | H/9 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | N. Ryan | 5,654 | 773 | 318 | 291 | .522 | 773 | 3.18 | 222 | 61 | 0 | 5326.0 | 3,880 | 1,884 | 2,151 | 314 | 2,748 | 156 | 0 | 75 | 22,310 | 275 | 9.55 | 4.64 | 2.06 | 0.53 | 25.3 | 12.3 | 1.24 | .265 | 3.63 | 6.56 |
| 2 |  | R. Johnson | 4,818 | 603 | 301 | 166 | .645 | 603 | 3.30 | 100 | 37 | 0 | 4103.0 | 3,320 | 1,504 | 1,692 | 408 | 1,491 | 188 | 0 | 37 | 16,937 | 109 | 10.57 | 3.27 | 3.23 | 0.89 | 28.4 | 8.8 | 1.17 | .290 | 3.71 | 7.28 |
| 3 |  | R. Clemens | 4,671 | 707 | 354 | 184 | .658 | 707 | 3.12 | 118 | 46 | 0 | 4913.2 | 4,182 | 1,706 | 1,884 | 363 | 1,579 | 159 | 0 | 63 | 20,227 | 143 | 8.56 | 2.89 | 2.96 | 0.66 | 23.1 | 7.8 | 1.17 | .284 | 3.45 | 7.66 |
| 4 |  | S. Carlton | 4,104 | 709 | 327 | 240 | .577 | 709 | 3.20 | 254 | 55 | 0 | 5165.1 | 4,616 | 1,835 | 2,096 | 405 | 1,814 | 53 | 0 | 145 | 21,457 | 177 | 7.15 | 3.16 | 2.26 | 0.71 | 19.1 | 8.5 | 1.24 | .279 | 3.65 | 8.04 |
| 5 |  | B. Blyleven | 3,694 | 685 | 286 | 248 | .536 | 685 | 3.31 | 242 | 60 | 0 | 4957.1 | 4,614 | 1,823 | 2,021 | 428 | 1,316 | 155 | 0 | 67 | 20,429 | 114 | 6.71 | 2.39 | 2.81 | 0.78 | 18.1 | 6.4 | 1.20 | .282 | 3.67 | 8.38 |
| 6 |  | T. Seaver | 3,634 | 647 | 310 | 203 | .604 | 647 | 2.86 | 231 | 61 | 0 | 4776.1 | 3,961 | 1,517 | 1,670 | 378 | 1,387 | 76 | 0 | 115 | 19,337 | 123 | 6.85 | 2.61 | 2.62 | 0.71 | 18.8 | 7.2 | 1.12 | .258 | 3.15 | 7.46 |
| 7 |  | J. Verlander | 3,554 | 556 | 266 | 159 | .626 | 556 | 3.33 | 26 | 9 | 0 | 3571.1 | 3,052 | 1,322 | 1,433 | 372 | 1,006 | 121 | 0 | 28 | 14,626 | 100 | 8.96 | 2.54 | 3.53 | 0.94 | 24.3 | 6.9 | 1.14 | .280 | 3.61 | 7.69 |
| 8 | | D. Sutton | 3,545 | 756 | 321 | 253 | .559 | 756 | 3.27 | 178 | 58 | 0 | 5248.1 | 4,670 | 1,905 | 2,095 | 469 | 1,333 | 81 | 0 | 96 | 21,500 | 110 | 6.08 | 2.29 | 2.66 | 0.80 | 16.5 | 6.2 | 1.14 | .261 | 3.59 | 8.01 |
| 9 |  | M. Scherzer | 3,525 | 490 | 223 | 125 | .641 | 490 | 3.29 | 12 | 5 | 0 | 3016.2 | 2,490 | 1,103 | 1,176 | 366 | 803 | 114 | 0 | 20 | 12,228 | 83 | 10.52 | 2.40 | 4.39 | 1.09 | 28.8 | 6.6 | 1.09 | .286 | 3.51 | 7.43 |
| 10 | | G. Perry | 3,372 | 690 | 305 | 252 | .548 | 690 | 3.10 | 303 | 53 | 0 | 5156.2 | 4,762 | 1,778 | 2,045 | 382 | 1,314 | 101 | 0 | 144 | 21,140 | 150 | 5.89 | 2.29 | 2.57 | 0.67 | 16.0 | 6.2 | 1.18 | .274 | 3.57 | 8.31 |
| 11 |  | G. Maddux | 3,366 | 740 | 355 | 226 | .611 | 740 | 3.15 | 109 | 35 | 0 | 5001.0 | 4,717 | 1,750 | 1,974 | 351 | 996 | 137 | 0 | 177 | 20,388 | 70 | 6.06 | 1.79 | 3.38 | 0.63 | 16.5 | 4.9 | 1.14 | .281 | 3.55 | 8.49 |
| 12 | | P. Niekro | 3,181 | 716 | 302 | 262 | .535 | 716 | 3.37 | 245 | 45 | 0 | 5149.2 | 4,815 | 1,928 | 2,227 | 465 | 1,703 | 116 | 0 | 73 | 21,585 | 207 | 5.56 | 2.98 | 1.87 | 0.81 | 14.7 | 7.9 | 1.27 | .270 | 3.89 | 8.42 |
| 13 |  | CC Sabathia | 3,091 | 560 | 251 | 161 | .609 | 560 | 3.74 | 38 | 12 | 0 | 3576.1 | 3,404 | 1,485 | 1,623 | 382 | 1,099 | 123 | 0 | 44 | 14,986 | 74 | 7.78 | 2.77 | 2.81 | 0.96 | 20.6 | 7.3 | 1.26 | .294 | 4.08 | 8.57 |
| 14 | | F. Jenkins | 3,082 | 594 | 278 | 218 | .560 | 594 | 3.32 | 267 | 49 | 0 | 4358.2 | 4,021 | 1,608 | 1,786 | 463 | 951 | 83 | 0 | 101 | 17,815 | 61 | 6.36 | 1.96 | 3.24 | 0.96 | 17.3 | 5.3 | 1.14 | .269 | 3.69 | 8.30 |
| 15 |  | C. Kershaw | 3,047 | 451 | 223 | 96 | .699 | 451 | 2.54 | 25 | 15 | 0 | 2850.1 | 2,191 | 804 | 881 | 235 | 711 | 46 | 0 | 27 | 11,261 | 108 | 9.62 | 2.25 | 4.29 | 0.74 | 27.1 | 6.3 | 1.02 | .271 | 2.78 | 6.92 |
| 16 |  | P. Martinez | 3,032 | 409 | 208 | 97 | .682 | 409 | 2.95 | 46 | 17 | 0 | 2720.0 | 2,151 | 893 | 979 | 233 | 705 | 136 | 0 | 26 | 10,955 | 60 | 10.03 | 2.33 | 4.30 | 0.77 | 27.7 | 6.4 | 1.05 | .280 | 3.24 | 7.12 |
| 17 |  | B. Gibson | 3,001 | 473 | 243 | 165 | .596 | 473 | 2.88 | 253 | 55 | 0 | 3728.0 | 3,130 | 1,192 | 1,345 | 247 | 1,241 | 98 | 0 | 106 | 15,368 | 101 | 7.24 | 3.00 | 2.42 | 0.60 | 19.5 | 8.1 | 1.17 | .267 | 3.25 | 7.56 |
| 18 | | C. Schilling | 2,953 | 436 | 206 | 134 | .606 | 436 | 3.45 | 83 | 20 | 0 | 3079.1 | 2,831 | 1,180 | 1,241 | 334 | 634 | 51 | 0 | 35 | 12,510 | 67 | 8.63 | 1.85 | 4.66 | 0.98 | 23.6 | 5.1 | 1.13 | .292 | 3.63 | 8.27 |
| 19 |  | Z. Greinke | 2,907 | 541 | 220 | 153 | .590 | 541 | 3.48 | 17 | 5 | 0 | 3316.0 | 3,142 | 1,282 | 1,377 | 360 | 742 | 77 | 0 | 22 | 13,579 | 99 | 7.89 | 2.01 | 3.92 | 0.98 | 21.4 | 5.5 | 1.17 | .293 | 3.74 | 8.53 |
| 20 | | M. Mussina | 2,812 | 536 | 270 | 153 | .638 | 536 | 3.68 | 57 | 23 | 0 | 3559.0 | 3,453 | 1,456 | 1,557 | 376 | 785 | 60 | 0 | 29 | 14,576 | 71 | 7.11 | 1.99 | 3.58 | 0.95 | 19.3 | 5.4 | 1.19 | .292 | 3.94 | 8.73 |
| 21 |  | J. Smoltz | 2,804 | 481 | 209 | 149 | .584 | 481 | 3.40 | 53 | 16 | 0 | 3211.2 | 2,869 | 1,214 | 1,317 | 271 | 960 | 56 | 0 | 79 | 13,256 | 136 | 7.86 | 2.69 | 2.92 | 0.76 | 21.2 | 7.2 | 1.19 | .283 | 3.69 | 8.04 |
| 22 | | M. Lolich | 2,735 | 496 | 209 | 187 | .528 | 496 | 3.44 | 195 | 41 | 0 | 3504.0 | 3,247 | 1,339 | 1,486 | 333 | 1,039 | 89 | 0 | 57 | 14,571 | 115 | 7.02 | 2.67 | 2.63 | 0.86 | 18.8 | 7.1 | 1.22 | .281 | 3.82 | 8.34 |
| 23 | | F. Tanana | 2,734 | 616 | 236 | 236 | .500 | 616 | 3.67 | 143 | 34 | 0 | 4136.1 | 4,019 | 1,688 | 1,893 | 445 | 1,227 | 128 | 0 | 110 | 17,413 | 114 | 5.95 | 2.67 | 2.23 | 0.97 | 15.7 | 7.0 | 1.27 | .278 | 4.12 | 8.74 |
| 24 |  | C. Sale | 2,648 | 338 | 154 | 94 | .621 | 338 | 2.97 | 17 | 4 | 0 | 2140.0 | 1,745 | 707 | 764 | 214 | 478 | 142 | 0 | 12 | 8,608 | 45 | 11.14 | 2.01 | 5.54 | 0.90 | 30.8 | 5.6 | 1.04 | .299 | 3.21 | 7.34 |
| 25 | | T. Glavine | 2,607 | 682 | 305 | 203 | .600 | 682 | 3.54 | 56 | 25 | 0 | 4413.1 | 4,298 | 1,734 | 1,900 | 356 | 1,500 | 66 | 0 | 145 | 18,604 | 65 | 5.32 | 3.06 | 1.74 | 0.73 | 14.0 | 8.1 | 1.31 | .280 | 3.87 | 8.76 |
StatMuse has game-level data for strikeouts going back to the 1901 season.
Some of the information used here was obtained free of charge from Retrosheet.
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