Since 2000, Justin Verlander has struck out the most hitters, with 3,553 strikeouts.

Interpreted as:

most strikeouts by a player since 2000 pitcher

	NAME	SO	G	W	L	W%	GS	ERA	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Justin Verlander J. Verlander	3,553	555	266	158	.627	555	3.32	26	9	0	3567.2	3,046	1,317	1,428	371	1,004	121	0	28	14,607	99	8.96	2.53	3.54	0.94	24.3	6.9	1.14	.280	3.60	79	3.43	81	7.68	310.9
2	Max Scherzer M. Scherzer	3,489	483	220	117	.653	474	3.22	12	5	0	2963.0	2,433	1,059	1,132	354	779	114	2	20	11,987	80	10.60	2.37	4.48	1.08	29.1	6.5	1.08	.287	3.44	77	3.23	78	7.39	302.5
3	CC Sabathia	3,093	561	251	161	.609	560	3.74	38	12	0	3577.1	3,404	1,485	1,623	382	1,099	123	0	44	14,989	74	7.78	2.76	2.81	0.96	20.6	7.3	1.26	.294	4.08	87	3.77	87	8.56	223.7
4	Clayton Kershaw C. Kershaw	3,052	455	223	96	.699	451	2.53	25	15	0	2855.1	2,193	804	881	235	713	46	1	28	11,279	108	9.62	2.25	4.28	0.74	27.1	6.3	1.02	.271	2.78	65	2.85	70	6.91	375.1
5	Zack Greinke Z. Greinke	2,979	586	225	156	.591	541	3.49	17	5	1	3389.1	3,207	1,315	1,410	367	762	79	8	25	13,877	101	7.91	2.02	3.91	0.97	21.5	5.5	1.17	.293	3.74	83	3.51	85	8.52	235
6	Chris Sale C. Sale	2,579	393	145	88	.622	312	3.01	16	3	12	2084.0	1,692	697	750	213	487	130	25	15	8,389	48	11.14	2.10	5.30	0.92	30.7	5.8	1.05	.297	3.24	70	2.87	68	7.31	303.3
7	Cole Hamels C. Hamels	2,560	423	163	122	.572	422	3.43	17	7	0	2698.0	2,424	1,027	1,103	310	767	100	0	43	11,115	57	8.54	2.56	3.34	1.03	23.0	6.9	1.18	.287	3.68	82	3.68	88	8.09	151.3
8	Felix Hernandez F. Hernandez	2,524	419	169	136	.554	418	3.42	25	11	0	2729.2	2,487	1,037	1,157	264	805	105	0	16	11,284	156	8.32	2.65	3.14	0.87	22.4	7.1	1.21	.293	3.81	84	3.52	85	8.20	181.5
9	Jon Lester J. Lester	2,488	452	200	117	.631	451	3.66	15	4	0	2740.0	2,610	1,114	1,215	294	892	90	0	13	11,487	63	8.17	2.93	2.79	0.97	21.7	7.8	1.28	.300	3.99	86	3.77	92	8.57	101.7
10	A.J. Burnett	2,480	428	160	155	.508	423	3.99	24	10	0	2690.0	2,482	1,194	1,305	260	1,075	143	1	33	11,483	161	8.30	3.60	2.31	0.87	21.6	9.4	1.32	.295	4.37	97	3.85	92	8.30	96.2
11	John Lackey J. Lackey	2,294	448	188	147	.561	446	3.92	18	8	0	2840.1	2,862	1,237	1,347	319	815	133	0	32	12,030	125	7.27	2.58	2.81	1.01	19.1	6.8	1.29	.300	4.27	92	3.94	94	9.07	79.6
12	Javier Vazquez J. Vazquez	2,284	391	151	137	.524	385	4.04	25	7	0	2513.0	2,434	1,129	1,212	322	643	73	4	52	10,504	72	8.18	2.30	3.55	1.15	21.7	6.1	1.22	.294	4.34	91	3.77	86	8.72	179
13	Gerrit Cole G. Cole	2,251	317	153	80	.657	317	3.18	8	5	0	1954.0	1,627	690	740	217	500	61	0	8	7,861	58	10.37	2.30	4.50	1.00	28.6	6.4	1.09	.292	3.41	79	3.16	77	7.49	213.5
14	James Shields J. Shields	2,234	407	145	139	.511	405	4.01	23	9	0	2616.0	2,581	1,167	1,267	361	746	97	1	22	10,993	107	7.69	2.57	2.99	1.24	20.3	6.8	1.27	.294	4.36	98	4.16	101	8.88	-13.5
15	Jake Peavy J. Peavy	2,207	388	152	126	.547	377	3.63	15	6	0	2377.0	2,134	960	1,011	259	708	78	3	42	9,838	46	8.36	2.68	3.12	0.98	22.4	7.2	1.20	.285	3.83	90	3.64	89	8.08	127.6
16	Adam Wainwright A. Wainwright	2,202	478	200	128	.610	411	3.53	28	11	3	2668.1	2,577	1,047	1,117	233	736	81	13	40	11,116	51	7.43	2.48	2.99	0.79	19.8	6.6	1.24	.298	3.77	88	3.53	87	8.69	152.8
17	Charlie Morton C. Morton	2,196	416	147	134	.523	409	4.13	3	2	0	2267.2	2,143	1,040	1,139	226	859	200	1	27	9,755	72	8.72	3.41	2.56	0.90	22.5	8.8	1.32	.306	4.52	103	3.89	97	8.51	36.6
18	Randy Johnson R. Johnson	2,182	287	143	78	.647	281	3.34	32	12	0	1885.1	1,616	699	790	212	484	89	3	22	7,686	34	10.42	2.31	4.51	1.01	28.4	6.3	1.11	.298	3.77	75	3.12	70	7.71	275.2
19	Bartolo Colon B. Colon	2,150	483	211	167	.558	472	4.11	30	10	0	2958.2	3,096	1,351	1,465	388	748	51	2	36	12,487	32	6.54	2.28	2.87	1.18	17.2	6.0	1.30	.296	4.46	96	4.14	97	9.42	44.8
20	David Price D. Price	2,076	400	157	82	.657	322	3.32	17	3	3	2143.2	1,930	790	865	221	562	63	19	16	8,807	40	8.72	2.36	3.69	0.93	23.6	6.4	1.16	.290	3.63	81	3.38	83	8.10	165.9
21	Yu Darvish Y. Darvish	2,075	297	115	93	.553	297	3.65	2	1	0	1778.0	1,460	721	756	231	563	83	0	8	7,305	83	10.50	2.85	3.69	1.17	28.4	7.7	1.14	.282	3.83	87	3.58	85	7.39	120
22	Madison Bumgarner M. Bumgarner	2,070	358	134	124	.519	355	3.47	16	7	0	2209.1	2,007	853	933	258	544	89	1	38	9,098	29	8.43	2.22	3.81	1.05	22.8	6.0	1.15	.285	3.80	90	3.62	94	8.18	50.1
23	Roy Halladay R. Halladay	2,022	378	194	98	.664	370	3.36	65	19	0	2586.0	2,481	966	1,055	215	511	77	4	27	10,566	50	7.04	1.78	3.96	0.75	19.1	4.8	1.16	.293	3.67	77	3.27	75	8.63	304.7
24	Lance Lynn L. Lynn	2,015	364	143	99	.591	340	3.74	4	2	1	2006.1	1,856	834	916	231	704	89	4	21	8,520	61	9.04	3.16	2.86	1.04	23.7	8.3	1.28	.296	4.11	91	3.82	93	8.33	67.8
25	Dan Haren D. Haren	2,013	391	153	131	.539	380	3.75	16	6	1	2419.2	2,357	1,009	1,105	305	500	67	4	39	10,022	98	7.49	1.86	4.03	1.13	20.1	5.0	1.18	.288	4.11	92	3.77	92	8.77	92.8