Jarren Duran has the most strikeouts against left-handed pitchers and with 100+ plate appearances this season, with 35 strikeouts.
| NAME | SO | PA | SEASON | TM | G | AB | H | 2B | 3B | HR | RBI | BB | HBP | TB | XBH | SH | SF | IBB | AVG | OBP | SLG | OPS | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | J. Duran | 35 | 122 | 2025 |  BOS | 62 | 117 | 26 | 5 | 3 | 0 | 13 | 4 | 1 | 37 | 8 | 0 | 0 | 0 | .222 | .254 | .316 | .570 |
| 2 |  | C. Yelich | 33 | 103 | 2025 |  MIL | 48 | 94 | 22 | 4 | 0 | 1 | 17 | 7 | 2 | 29 | 5 | 0 | 0 | 0 | .234 | .301 | .309 | .609 |
| 3 |  | E. De La Cruz | 30 | 103 | 2025 |  CIN | 56 | 95 | 20 | 3 | 0 | 5 | 14 | 8 | 0 | 38 | 8 | 0 | 0 | 2 | .211 | .272 | .400 | .672 |
| 4 |  | J. Wood | 30 | 112 | 2025 |  WSH | 57 | 102 | 27 | 5 | 0 | 6 | 19 | 10 | 0 | 50 | 11 | 0 | 0 | 0 | .265 | .330 | .490 | .821 |
| 5 |  | K. Schwarber | 30 | 119 | 2025 |  PHI | 56 | 97 | 27 | 2 | 1 | 12 | 20 | 19 | 3 | 67 | 15 | 0 | 0 | 0 | .278 | .412 | .691 | 1.102 |
| 6 |  | S. Ohtani | 30 | 112 | 2025 |  LAD | 52 | 106 | 33 | 6 | 3 | 4 | 10 | 6 | 0 | 57 | 13 | 0 | 0 | 0 | .311 | .348 | .538 | .886 |
| 7 |  | G. Henderson | 29 | 100 | 2025 |  BAL | 56 | 95 | 20 | 3 | 0 | 1 | 7 | 4 | 1 | 26 | 4 | 0 | 0 | 0 | .211 | .250 | .274 | .524 |
| 8 |  | L. Nootbaar | 29 | 122 | 2025 |  STL | 52 | 103 | 23 | 4 | 0 | 2 | 5 | 16 | 3 | 33 | 6 | 0 | 0 | 0 | .223 | .344 | .320 | .665 |
| 9 |  | R. Devers | 29 | 128 | 2025 | TOT | 61 | 111 | 32 | 7 | 0 | 5 | 24 | 14 | 3 | 54 | 12 | 0 | 0 | 3 | .288 | .383 | .486 | .869 |
| 10 | | B. Donovan | 21 | 102 | 2025 | STL | 44 | 93 | 22 | 6 | 0 | 2 | 9 | 6 | 3 | 34 | 8 | 0 | 0 | 0 | .237 | .304 | .366 | .670 |
| 11 |  | T. Turner | 16 | 100 | 2025 | PHI | 48 | 94 | 29 | 3 | 2 | 3 | 8 | 5 | 1 | 45 | 8 | 0 | 0 | 0 | .309 | .350 | .479 | .829 |
| 12 |  | K. Tucker | 14 | 105 | 2025 |  CHC | 56 | 92 | 26 | 4 | 1 | 6 | 18 | 12 | 1 | 50 | 11 | 0 | 0 | 0 | .283 | .371 | .543 | .915 |
StatMuse has event-level data for plate appearances and strikeouts going back to the 1974 season.
Some of the information used here was obtained free of charge from Retrosheet.
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