I didn't find anything for this season, but Rafael Devers had the most strikeouts against left-handed pitchers and with 100+ plate appearances in 2024, with 71 strikeouts.
| NAME | SO | PA | SEASON | TM | G | AB | H | 2B | 3B | HR | RBI | BB | HBP | TB | XBH | SH | SF | IBB | AVG | OBP | SLG | OPS | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | R. Devers | 71 | 224 | 2024 |  BOS | 114 | 204 | 49 | 11 | 3 | 4 | 20 | 17 | 2 | 78 | 18 | 0 | 1 | 1 | .240 | .304 | .382 | .686 |
| 2 |  | E. De La Cruz | 69 | 217 | 2024 |  CIN | 116 | 192 | 43 | 7 | 0 | 6 | 20 | 19 | 4 | 68 | 13 | 2 | 0 | 0 | .224 | .307 | .354 | .661 |
| 3 |  | K. Schwarber | 67 | 248 | 2024 |  PHI | 104 | 210 | 63 | 4 | 0 | 12 | 38 | 36 | 2 | 103 | 16 | 0 | 0 | 0 | .300 | .407 | .490 | .898 |
| 4 |  | E. Tovar | 62 | 209 | 2024 |  COL | 103 | 193 | 50 | 12 | 1 | 8 | 22 | 12 | 1 | 88 | 21 | 0 | 2 | 1 | .259 | .303 | .456 | .759 |
| 5 |  | E. Suárez | 61 | 194 | 2024 |  ARI | 86 | 168 | 43 | 3 | 0 | 10 | 26 | 22 | 1 | 76 | 13 | 0 | 3 | 0 | .256 | .340 | .452 | .793 |
| 6 |  | R. McMahon | 59 | 196 | 2024 | COL | 101 | 176 | 46 | 7 | 0 | 6 | 16 | 18 | 2 | 71 | 13 | 0 | 0 | 0 | .261 | .337 | .403 | .740 |
| 7 |  | S. Ohtani | 58 | 249 | 2024 |  LAD | 114 | 226 | 65 | 12 | 2 | 12 | 39 | 20 | 2 | 117 | 26 | 0 | 1 | 0 | .288 | .349 | .518 | .867 |
| 8 |  | J. Duran | 56 | 230 | 2024 | BOS | 116 | 208 | 53 | 5 | 1 | 4 | 18 | 17 | 3 | 72 | 10 | 1 | 1 | 0 | .255 | .319 | .346 | .665 |
| 9 |  | G. Henderson | 54 | 217 | 2024 |  BAL | 103 | 183 | 47 | 7 | 4 | 8 | 25 | 28 | 3 | 86 | 19 | 0 | 3 | 1 | .257 | .359 | .470 | .829 |
| 10 |  | C. Rafaela | 54 | 152 | 2024 | BOS | 89 | 142 | 30 | 6 | 2 | 3 | 11 | 7 | 2 | 49 | 11 | 1 | 0 | 1 | .211 | .258 | .345 | .603 |
| 11 |  | B. Harper | 53 | 226 | 2024 | PHI | 105 | 196 | 59 | 16 | 0 | 9 | 31 | 28 | 0 | 102 | 25 | 1 | 1 | 1 | .301 | .387 | .520 | .907 |
| 12 |  | J. Chisholm Jr. | 52 | 210 | 2024 | TOT | 98 | 189 | 47 | 6 | 1 | 6 | 28 | 17 | 3 | 73 | 13 | 0 | 1 | 0 | .249 | .319 | .386 | .705 |
| 13 |  | C. Cowser | 51 | 146 | 2024 | BAL | 80 | 134 | 30 | 4 | 1 | 5 | 8 | 9 | 2 | 51 | 10 | 0 | 1 | 0 | .224 | .281 | .381 | .661 |
| 14 |  | A. GarcÃa | 50 | 162 | 2024 |  TEX | 80 | 143 | 33 | 8 | 0 | 7 | 26 | 13 | 2 | 62 | 15 | 0 | 4 | 2 | .231 | .296 | .434 | .730 |
| 15 |  | D. Schneider | 49 | 138 | 2024 |  TOR | 67 | 121 | 20 | 4 | 1 | 3 | 15 | 12 | 1 | 35 | 8 | 0 | 4 | 0 | .165 | .239 | .289 | .528 |
| 16 | | T. O'Neill | 49 | 156 | 2024 | BOS | 75 | 128 | 40 | 8 | 0 | 16 | 29 | 26 | 1 | 96 | 24 | 0 | 1 | 4 | .313 | .429 | .750 | 1.179 |
| 17 |  | CJ Abrams | 49 | 188 | 2024 |  WSH | 86 | 174 | 51 | 10 | 3 | 5 | 22 | 9 | 4 | 82 | 18 | 0 | 1 | 0 | .293 | .340 | .471 | .812 |
| 18 |  | C. Carroll | 48 | 209 | 2024 | ARI | 101 | 183 | 40 | 5 | 3 | 8 | 24 | 16 | 5 | 75 | 16 | 3 | 2 | 0 | .219 | .296 | .410 | .706 |
| 19 |  | M. Haniger | 47 | 145 | 2024 |  SEA | 68 | 135 | 24 | 1 | 0 | 3 | 10 | 10 | 0 | 34 | 4 | 0 | 0 | 0 | .178 | .234 | .252 | .486 |
| 20 |  | M. Ozuna | 47 | 163 | 2024 |  ATL | 69 | 141 | 45 | 10 | 0 | 5 | 24 | 21 | 0 | 70 | 15 | 0 | 0 | 0 | .319 | .407 | .496 | .904 |
| 21 |  | B. De La Cruz | 47 | 188 | 2024 | TOT | 89 | 179 | 51 | 13 | 0 | 4 | 24 | 6 | 1 | 76 | 17 | 0 | 2 | 0 | .285 | .309 | .425 | .733 |
| 22 |  | D. Moore | 47 | 176 | 2024 | SEA | 85 | 144 | 33 | 12 | 1 | 4 | 14 | 25 | 4 | 59 | 17 | 0 | 3 | 1 | .229 | .352 | .410 | .762 |
| 23 |  | B. Reynolds | 47 | 203 | 2024 |  PIT | 103 | 188 | 50 | 8 | 0 | 6 | 29 | 13 | 1 | 76 | 14 | 0 | 1 | 1 | .266 | .315 | .404 | .720 |
| 24 |  | O. Cruz | 47 | 154 | 2024 | PIT | 102 | 143 | 32 | 8 | 1 | 6 | 21 | 8 | 1 | 60 | 15 | 0 | 2 | 0 | .224 | .266 | .420 | .686 |
| 25 |  | T. Hernández | 46 | 171 | 2024 | LAD | 78 | 155 | 45 | 9 | 1 | 11 | 28 | 14 | 2 | 89 | 21 | 0 | 0 | 3 | .290 | .357 | .574 | .931 |
StatMuse has event-level data for plate appearances and strikeouts going back to the 1974 season.
Some of the information used here was obtained free of charge from Retrosheet.
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