Zack Wheeler faced the most batters in a game in 2021, with 35 batters faced versus the Rays on August 25, 2021.

Interpreted as:

most tbf by a pitcher in a regular-season game 2021

	NAME	TBF	DATE	TM		OPP	DEC	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	WP
1	Zack Wheeler Z. Wheeler	35	8/25/2021	PHI	vs	TBR	L	1	5.63	10	0	0	0	8.0	10	5	7	2	0	0	0	0	0
2	Patrick Corbin P. Corbin	34	6/15/2021	WSH	vs	PIT	W	1	1.08	7	0	0	0	8.1	8	1	1	0	1	0	0	0	0
3	Shohei Ohtani S. Ohtani	33	9/19/2021	LAA	vs	OAK		1	2.25	10	0	0	0	8.0	5	2	2	2	3	1	0	2	0
4	J.A. Happ	33	7/18/2021	MIN	@	DET	L	1	9.00	4	0	0	0	7.0	11	7	7	2	1	0	0	0	0
5	Ryan Yarbrough R. Yarbrough	33	6/3/2021	TBR	@	NYY	W	1	2.00	6	1	0	0	9.0	6	2	2	2	0	0	0	0	0
6	Shane Bieber S. Bieber	33	4/18/2021	CLE	@	CIN	W	1	3.38	13	0	0	0	8.0	6	3	3	1	2	0	0	0	1
7	Joe Musgrove J. Musgrove	32	8/27/2021	SDP	@	LAA	W	1	0.00	9	1	1	0	9.0	3	0	0	0	2	0	0	0	0
8	Nick Pivetta N. Pivetta	32	7/19/2021	BOS	@	TOR	W	1	5.40	4	0	0	0	6.2	11	4	4	1	2	1	0	0	0
9	Sandy Alcantara S. Alcantara	32	6/16/2021	MIA	@	STL	L	1	0.00	7	1	0	0	8.1	6	0	1	0	1	1	0	0	0
10	Zack Greinke Z. Greinke	32	6/4/2021	HOU	@	TOR	W	1	1.00	3	1	0	0	9.0	6	1	1	1	1	0	0	0	0
11	Lance Lynn L. Lynn	32	4/8/2021	CWS	vs	KCR	W	1	0.00	11	1	1	0	9.0	5	0	0	0	0	0	0	0	0
12	Wily Peralta W. Peralta	31	10/1/2021	DET	@	CWS	L	1	3.00	3	0	0	0	6.0	9	2	5	1	3	1	0	0	0
13	Sandy Alcantara S. Alcantara	31	9/8/2021	MIA	vs	NYM		1	1.00	14	0	0	0	9.0	4	1	1	1	1	1	0	0	0
14	Adam Wainwright A. Wainwright	31	9/8/2021	STL	vs	LAD	W	1	4.32	4	0	0	0	8.1	7	4	4	1	0	0	0	0	0
15	José Suarez J. Suarez	31	9/4/2021	LAA	vs	TEX	W	1	1.00	8	1	0	0	9.0	5	1	1	0	0	0	0	0	1
16	Aaron Nola A. Nola	31	8/21/2021	PHI	@	SDP		1	2.08	11	0	0	0	8.2	2	2	3	1	2	0	0	0	0
17	Zack Wheeler Z. Wheeler	31	8/3/2021	PHI	@	WSH	W	1	4.91	5	0	0	0	7.1	8	4	4	1	1	0	0	0	0
18	Aaron Nola A. Nola	31	7/25/2021	PHI	vs	ATL	W	1	1.04	9	0	0	0	8.2	4	1	1	1	0	0	0	0	0
19	Corbin Burnes C. Burnes	31	7/18/2021	MIL	@	CIN	W	1	0.00	12	0	0	0	8.1	5	0	0	0	1	0	0	0	0
20	Gerrit Cole G. Cole	31	7/10/2021	NYY	@	HOU	W	1	0.00	12	1	1	0	9.0	3	0	0	0	2	0	0	0	0
21	Wade Miley W. Miley	31	7/9/2021	CIN	@	MIL	W	1	0.00	4	0	0	0	8.0	7	0	0	0	3	0	0	0	0
22	Lance McCullers Jr. L. McCullers Jr.	31	7/8/2021	HOU	vs	OAK	L	1	2.57	8	0	0	0	7.0	7	2	2	0	2	0	0	0	1
23	Anthony DeSclafani A. DeSclafani	31	7/4/2021	SFG	@	ARI	W	1	2.08	7	0	0	0	8.2	6	2	2	0	2	0	0	0	0
24	Sandy Alcantara S. Alcantara	31	6/22/2021	MIA	vs	TOR		1	1.13	3	0	0	0	8.0	5	1	1	0	1	1	0	0	1
25	Vladimir Gutierrez V. Gutierrez	31	6/9/2021	CIN	vs	MIL	W	1	2.57	7	0	0	0	7.0	6	2	2	0	3	1	0	0	1