The San Francisco Giants have won the most games by a team, with 11,565 wins.

Interpreted as:

most team regular-season wins from an pitching opener

	TEAM	W	L	W%	G	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Giants	11,565	10,031	.536	21,772	21,772	3.58	108,081	7,695	1,020	3,427	194282.2	189,304	77,347	93,197	13,955	66,653	5,046	3,844	825,445	5,882	5.01	3.09	1.62	0.65	13.1	8.1	1.32	.278	4.32	8.77
2	Dodgers	11,455	10,087	.532	21,688	21,688	3.53	113,230	7,905	1,174	3,348	194024.1	186,276	76,084	91,683	13,191	66,378	5,248	3,424	820,766	5,615	5.25	3.08	1.71	0.61	13.8	8.1	1.30	.278	4.25	8.64
3	Cubs	11,355	10,780	.513	22,304	22,304	3.70	110,719	8,282	1,015	3,124	199194.1	197,586	81,810	99,108	14,552	68,798	5,499	3,745	850,619	5,826	5.00	3.11	1.61	0.66	13.0	8.1	1.34	.281	4.48	8.93
4	Braves	11,136	10,972	.504	22,265	22,265	3.67	104,293	8,660	949	3,061	198739.2	198,278	80,996	97,981	13,675	67,204	4,846	3,795	845,860	5,782	4.72	3.04	1.55	0.62	12.3	7.9	1.34	.281	4.44	8.98
5	Reds	10,959	10,790	.504	21,889	21,889	3.77	102,787	7,850	935	3,304	195288.1	195,139	81,785	97,446	14,467	67,059	5,719	3,530	833,075	5,476	4.74	3.09	1.53	0.67	12.3	8.0	1.34	.281	4.49	8.99
6	Pirates	10,851	10,848	.500	21,847	21,847	3.76	100,127	7,797	979	3,154	194647.2	196,584	81,295	97,423	13,082	65,112	5,616	3,947	831,087	5,568	4.63	3.01	1.54	0.60	12.0	7.8	1.34	.284	4.50	9.09
7	Yankees	10,805	8,167	.570	19,061	19,061	3.65	100,344	5,871	998	3,636	170396.1	163,988	69,193	79,501	13,292	60,646	4,385	2,260	720,121	4,535	5.30	3.20	1.65	0.70	13.9	8.4	1.32	.278	4.20	8.66
8	Cardinals	10,528	9,990	.513	20,655	20,655	3.74	98,143	6,821	995	3,314	184502.2	184,739	76,595	90,452	13,109	63,671	5,257	3,588	786,440	4,892	4.79	3.11	1.54	0.64	12.5	8.1	1.35	.283	4.41	9.01
9	Phillies	10,232	11,341	.474	21,696	21,696	3.99	104,558	7,664	927	2,949	193113.2	198,978	85,511	102,050	14,589	67,644	5,791	3,583	831,468	5,705	4.87	3.15	1.55	0.68	12.6	8.1	1.38	.289	4.76	9.27
10	Red Sox	9,979	9,288	.518	19,351	19,351	3.92	99,602	5,916	912	3,165	172814.0	173,565	75,362	86,782	13,593	62,922	5,152	2,493	739,991	4,484	5.19	3.28	1.58	0.71	13.5	8.5	1.37	.286	4.52	9.04
11	Guardians	9,877	9,389	.513	19,358	19,358	3.83	99,256	6,082	982	3,079	172925.0	171,676	73,602	85,272	13,195	64,175	4,694	2,820	738,266	4,840	5.17	3.34	1.55	0.69	13.4	8.7	1.36	.285	4.44	8.93
12	Tigers	9,706	9,584	.503	19,385	19,385	4.00	95,680	6,175	901	2,972	172884.2	174,272	76,778	88,695	14,608	64,507	5,209	2,942	742,373	5,003	4.98	3.36	1.48	0.76	12.9	8.7	1.38	.284	4.62	9.07
13	White Sox	9,609	9,645	.499	19,358	19,358	3.80	94,788	5,938	1,015	3,241	173047.1	170,798	73,065	84,221	13,570	61,858	4,556	2,536	736,148	4,829	4.93	3.22	1.53	0.71	12.9	8.4	1.34	.280	4.38	8.88
14	Athletics	9,350	9,885	.486	19,324	19,324	4.00	94,668	5,699	853	3,092	172228.0	171,441	76,573	88,369	14,232	66,716	4,958	2,676	739,219	5,330	4.95	3.49	1.42	0.74	12.8	9.0	1.38	.281	4.62	8.96
15	Twins	9,285	9,974	.482	19,370	19,370	3.99	94,836	5,846	882	3,085	172571.2	175,823	76,592	88,383	14,037	61,172	4,690	2,242	738,985	5,049	4.95	3.19	1.55	0.73	12.8	8.3	1.37	.287	4.61	9.17
16	Orioles	9,134	10,116	.474	19,361	19,361	4.05	91,830	5,886	889	2,978	172617.2	174,602	77,748	89,038	14,593	65,061	4,574	2,443	740,251	4,572	4.79	3.39	1.41	0.76	12.4	8.8	1.39	.284	4.64	9.10
17	Angels	5,043	5,140	.495	10,186	10,186	4.01	63,774	1,307	347	2,373	91018.2	88,256	40,547	44,790	9,773	34,399	2,998	2,346	388,860	3,547	6.31	3.40	1.85	0.97	16.4	8.8	1.35	.282	4.43	8.73
18	Astros	5,034	4,988	.502	10,027	10,027	3.80	68,569	1,137	343	2,250	89803.1	85,634	37,883	42,031	8,520	31,772	2,736	2,646	381,329	3,344	6.87	3.18	2.16	0.85	18.0	8.3	1.31	.286	4.21	8.58
19	Mets	4,845	5,168	.484	10,021	10,021	3.80	66,497	1,094	332	2,240	89656.2	85,985	37,855	42,116	8,797	31,961	2,713	3,176	381,168	2,823	6.68	3.21	2.08	0.88	17.4	8.4	1.32	.285	4.23	8.63
20	Rangers	4,842	5,325	.476	10,175	10,175	4.28	61,403	1,191	286	2,210	90613.1	91,198	43,132	47,862	9,999	34,941	3,058	2,340	391,594	3,386	6.10	3.47	1.76	0.99	15.7	8.9	1.39	.288	4.75	9.06
21	Brewers	4,332	4,555	.487	8,891	8,891	4.14	54,762	929	208	2,156	79326.0	79,165	36,505	40,330	8,931	29,357	2,550	2,276	341,036	2,779	6.21	3.33	1.87	1.01	16.1	8.6	1.37	.286	4.58	8.98
22	Nationals	4,287	4,596	.483	8,887	8,887	3.96	57,578	790	251	2,163	79391.0	77,042	34,897	38,708	8,110	29,148	2,620	2,717	339,339	2,715	6.53	3.30	1.98	0.92	17.0	8.6	1.34	.285	4.39	8.73
23	Royals	4,235	4,646	.477	8,883	8,883	4.25	52,473	955	240	2,034	79062.2	80,390	37,372	40,994	8,370	29,039	2,528	1,886	340,486	3,081	5.97	3.31	1.81	0.95	15.4	8.5	1.38	.290	4.67	9.15
24	Padres	4,154	4,736	.467	8,892	8,892	3.96	58,039	668	203	2,144	79528.0	77,272	34,992	38,881	8,246	29,345	2,313	3,075	339,955	2,696	6.57	3.32	1.98	0.93	17.1	8.6	1.34	.285	4.40	8.74
25	Blue Jays	3,784	3,812	.498	7,599	7,599	4.22	49,740	650	162	1,779	67814.0	67,350	31,781	34,760	7,886	25,120	2,427	1,616	291,124	2,432	6.60	3.33	1.98	1.05	17.1	8.6	1.36	.289	4.61	8.94