Walter Johnson has the most career home wins by a pitcher against a team, with 37 wins against the White Sox.

Interpreted as:

most regular-season wins by a player at home team

	NAME	W	OPP	L	W%	G	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Walter Johnson W. Johnson	37	White Sox	16	.698	61	50	1.31	302	41	10	2	467.2	327		125	8	91	14	10			8	5.81	1.75	3.32	0.15		5.0	0.89	.230	2.41	6.29
2	Warren Spahn W. Spahn	36	Cardinals	24	.600	68	61	2.60	216	36	8	3	511.1	451	148	172	29	121	4	7	5	2,076	13	3.80	2.13	1.79	0.51	10.4	5.8	1.12	.247	3.03	7.94
3	Grover Alexander G. Alexander	36	Braves	9	.800	56	44	2.06	169	36	5	3	406.2	357		125	15	65	4	11		1,613	2	3.74	1.44	2.60	0.33	10.5	4.0	1.04	.251	2.77	7.90
4	Walter Johnson W. Johnson	36	Athletics	16	.692	59	50	1.38	290	39	19	3	444.1	358		128	7	101	12	8			12	5.87	2.05	2.87	0.14		5.7	1.03	.257	2.59	7.25
5	Walter Johnson W. Johnson	35	Tigers	20	.636	61	52	1.58	312	41	8	2	478.1	391		164	4	125	19	9			12	5.87	2.35	2.50	0.08		6.6	1.08	.271	3.09	7.36
6	Grover Alexander G. Alexander	34	Reds	12	.739	50	43	1.83	172	34	10	1	398.0	324		110	6	76	6	7			2	3.89	1.72	2.26	0.14		4.9	1.01	.247	2.49	7.33
7	Lefty Grove L. Grove	33	Tigers	6	.846	47	38	2.83	201	30	5	1	356.0	324	112	126	16	99	5	4		1,464	3	5.08	2.50	2.03	0.40	13.7	6.8	1.19	.269	3.19	8.19
8	Walter Johnson W. Johnson	33	Browns	16	.673	56	47	1.35	272	42	8	0	441.0	371		128	4	89	14	7			9	5.55	1.82	3.06	0.08		5.1	1.04	.269	2.61	7.57
9	Walter Johnson W. Johnson	33	Red Sox	16	.673	58	47	1.55	265	39	6	4	430.0	355		114	6	87	16	10			8	5.55	1.82	3.05	0.13		5.1	1.03	.262	2.39	7.43
10	Eddie Plank E. Plank	32	Tigers	12	.727	49	44	1.15	200	35	5	0	384.0	345		117	2	78	10	5			8	4.69	1.83	2.56	0.05		5.4	1.10	.297	2.74	8.09
11	Christy Mathewson C. Mathewson	32	Reds	6	.842	44	38	0.88	178	34	7	3	346.0	286		90	10	33	2	6			4	4.63	0.86	5.39	0.26		2.5	0.92	.253	2.34	7.44
12	Warren Spahn W. Spahn	30	Reds	16	.652	55	47	3.00	187	28	6	1	372.0	336	124	137	36	99	6	6	9	1,532	7	4.52	2.40	1.89	0.87	12.2	6.5	1.17	.249	3.31	8.13
13	Walter Johnson W. Johnson	30	Indians	18	.625	55	48	1.74	236	35	10	1	424.1	363		126	3	86	18	6			12	5.01	1.82	2.74	0.06		5.1	1.06	.265	2.67	7.70
14	Christy Mathewson C. Mathewson	30	Phillies	10	.750	43	40	0.51	189	30	9	0	333.2	283		98	5	74	6	3			10	5.10	2.00	2.55	0.13		5.8	1.07	.277	2.64	7.63
15	Warren Spahn W. Spahn	29	Giants	19	.604	56	51	2.94	223	34	6	1	422.1	363	138	148	45	117	4	4	0	1,711	4	4.75	2.49	1.91	0.96	13.0	6.8	1.14	.241	3.15	7.74
16	Early Wynn E. Wynn	29	Orioles	10	.744	46	43	2.69	168	24	2	0	338.1	291	101	123	14	130	1	3	1	1,411	5	4.47	3.46	1.29	0.37	11.9	9.2	1.24	.252	3.27	7.74
17	Walter Johnson W. Johnson	29	Yankees	15	.659	47	42	1.53	226	36	12	1	377.2	282		103	8	80	11	5			9	5.39	1.91	2.83	0.19		5.4	0.96	.237	2.45	6.72
18	Burleigh Grimes B. Grimes	28	Phillies	8	.778	45	38	2.98	132	26	6	2	320.1	333	106	143	15	83	10	5		1,353	3	3.71	2.33	1.59	0.42	9.8	6.1	1.30	.286	4.02	9.36
19	Grover Alexander G. Alexander	28	Robins	11	.718	45	40	1.92	166	32	9	2	361.2	320		106	9	60	3	4		1,433	4	4.13	1.49	2.77	0.22	11.6	4.2	1.05	.260	2.64	7.96
20	Eddie Plank E. Plank	28	Red Sox	12	.700	48	43	1.26	177	36	6	1	379.1	310		109	4	80	14	4			6	4.20	1.90	2.21	0.09		5.6	1.03	.267	2.59	7.36
21	Christy Mathewson C. Mathewson	28	Pirates	20	.583	55	48	0.84	213	30	4	1	397.2	359		149	12	54	5	7			15	4.82	1.22	3.94	0.27		3.5	1.04	.276	3.37	8.12
22	Mel Harder M. Harder	27	Red Sox	15	.643	49	44	3.17	147	20	4	2	337.1	342	119	150	11	99	2	5		1,430	1	3.92	2.64	1.48	0.29	10.3	6.9	1.31	.283	4.00	9.12
23	Lefty Grove L. Grove	27	Indians	8	.771	40	34	2.84	176	27	4	3	307.1	310	97	108	12	81	3	5		1,285	0	5.15	2.37	2.17	0.35	13.7	6.3	1.27	.294	3.16	9.08
24	Burleigh Grimes B. Grimes	27	Reds	15	.643	46	38	3.22	112	26	7	1	321.0	329		134	7	80	5	5		1,330	5	3.14	2.24	1.40	0.20	8.4	6.0	1.27	.286	3.76	9.22
25	Grover Alexander G. Alexander	27	Giants	23	.540	58	49	3.05	164	32	6	2	431.0	451		196	21	103	7	5		1,796	4	3.42	2.15	1.59	0.44	9.1	5.7	1.29	.286	4.09	9.42

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StatMuse has game-level data for pitcher wins going back to the 1901 season.

Some of the information used here was obtained free of charge from Retrosheet.

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TEAM	W	L	PCT	GB
Guardians	88	74	.543
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Royals	82	80	.506	6.0
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Schedule

DATE	MATCHUP			TIME (ET)
Thu 3/26	MIN	@	BAL	3:05 PM
Sat 3/28	MIN	@	BAL	4:05 PM
Sun 3/29	MIN	@	BAL	1:35 PM
Mon 3/30	MIN	@	KCR	4:10 PM
Wed 4/1	MIN	@	KCR	7:40 PM

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MLB 2025 Standings

NL East	W	L	PCT	GB
Phillies - y	96	66	.593
Mets	83	79	.512	13.0
Marlins	79	83	.488	17.0
Braves	76	86	.469	20.0
Nationals	66	96	.407	30.0
NL Central	W	L	PCT	GB
Brewers - y	97	65	.599
Cubs - w	92	70	.568	5.0
Reds - w	83	79	.512	14.0
Cardinals	78	84	.481	19.0
Pirates	71	91	.438	26.0
NL West	W	L	PCT	GB
Dodgers - y	93	69	.574
Padres - w	90	72	.556	3.0
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Diamondbacks	80	82	.494	13.0
Rockies	43	119	.265	50.0

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Blue Jays - y	94	68	.580
Yankees - w	94	68	.580
Red Sox - w	89	73	.549	5.0
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Guardians - y	88	74	.543
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Astros	87	75	.537	3.0
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Athletics	76	86	.469	14.0
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Tue 9/16	CIN	@	STL	6-2
Tue 9/16	ATL	@	WSH	9-4
Tue 9/16	ATH	@	BOS	4-5
Tue 9/16	TOR	@	TBR	1-2
Tue 9/16	SEA	@	KCR	5-7

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DATE	MATCHUP			TIME (ET)
Wed 3/25	NYY	@	SFG	8:05 PM
Thu 3/26	LAA	@	HOU	4:00 AM
Thu 3/26	WSH	@	CHC	4:00 AM
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Walter Johnson has the most career home wins by a pitcher against a team, with 37 wins against the White Sox.

Interpreted as:

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