Since 2020, the Los Angeles Dodgers have the most wins by a team, with 483 wins.

Interpreted as:

most regular-season wins by an MLB team since 2020

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Dodgers	483	263	.647	746	25,342	3,980	6,449	1,325	116	1,109	3,829	2,836	351	6,272	460	98	28,824	11,333	2,550	54	241	132	451	.254	.335	.447	.782
2	Braves	435	309	.585	744	25,274	3,727	6,433	1,315	76	1,146	3,586	2,406	290	6,596	394	106	28,192	11,338	2,537	48	174	95	491	.255	.324	.449	.773
3	Astros	426	317	.573	743	25,282	3,591	6,491	1,278	81	947	3,454	2,401	300	5,540	379	112	28,244	10,772	2,306	57	204	98	575	.257	.326	.426	.752
4	Yankees	421	324	.565	745	24,687	3,527	5,927	1,052	62	1,088	3,362	2,868	277	6,435	407	124	28,072	10,367	2,202	49	191	106	606	.240	.324	.420	.744
5	Rays	421	324	.565	745	25,034	3,417	6,074	1,269	115	849	3,245	2,451	338	6,771	613	191	28,021	10,120	2,233	29	169	71	431	.243	.317	.404	.721
6	Brewers	414	332	.555	746	24,811	3,390	5,897	1,146	93	861	3,234	2,703	324	6,685	585	143	28,071	9,812	2,100	68	165	99	535	.238	.319	.395	.714
7	Phillies	404	341	.542	745	25,150	3,548	6,348	1,240	122	942	3,400	2,468	291	6,387	541	118	28,188	10,658	2,304	91	188	117	504	.252	.324	.424	.748
8	Padres	403	341	.542	744	24,928	3,414	6,202	1,236	86	853	3,265	2,590	277	5,768	504	143	28,111	10,169	2,175	124	192	110	546	.249	.324	.408	.732
9	Mariners	402	342	.540	744	24,714	3,260	5,710	1,109	62	902	3,127	2,613	440	6,968	498	137	27,985	9,649	2,073	45	173	60	468	.231	.314	.390	.704
10	Giants	400	346	.536	746	25,006	3,369	6,025	1,218	105	895	3,227	2,539	330	6,692	296	84	28,145	10,138	2,218	79	191	103	530	.241	.317	.405	.722
11	Guardians	397	347	.534	744	24,883	3,190	6,055	1,206	107	740	3,020	2,201	325	5,654	581	145	27,702	9,695	2,053	85	208	133	499	.243	.311	.390	.700
12	Blue Jays	395	350	.530	745	25,265	3,475	6,467	1,330	75	920	3,334	2,377	281	5,778	376	120	28,145	10,707	2,325	50	172	70	567	.256	.325	.424	.749
13	Mets	392	354	.525	746	24,866	3,360	6,166	1,177	98	897	3,218	2,383	471	6,100	385	100	27,973	10,230	2,172	85	168	86	541	.248	.323	.411	.735
14	Cardinals	386	358	.519	744	24,910	3,283	6,175	1,220	84	855	3,149	2,402	339	5,978	422	123	27,930	10,128	2,159	82	197	81	495	.248	.320	.407	.727
15	Twins	374	372	.501	746	25,078	3,366	6,120	1,258	89	946	3,209	2,405	376	6,550	279	89	28,089	10,394	2,293	41	189	66	551	.244	.317	.414	.732
16	Red Sox	373	374	.499	747	25,600	3,570	6,595	1,525	96	877	3,404	2,295	305	6,594	424	127	28,431	10,943	2,498	46	185	107	528	.258	.324	.427	.751
17	Cubs	367	379	.492	746	24,929	3,405	6,031	1,162	133	864	3,241	2,503	386	6,672	552	156	28,098	10,051	2,159	97	183	75	506	.242	.319	.403	.722
18	Orioles	365	379	.491	744	25,107	3,334	6,156	1,261	112	904	3,200	2,190	302	6,404	398	124	27,853	10,353	2,277	68	186	57	446	.245	.311	.412	.724
19	Tigers	355	389	.477	744	24,867	3,054	5,907	1,093	158	726	2,939	2,135	238	6,764	331	105	27,480	9,494	1,977	49	191	42	483	.238	.302	.382	.684
20	Reds	354	393	.474	747	24,784	3,344	5,925	1,191	103	880	3,199	2,439	425	6,690	563	172	27,898	9,962	2,174	86	164	51	507	.239	.316	.402	.718
21	Diamondbacks	344	402	.461	746	25,068	3,473	6,137	1,293	154	800	3,294	2,511	308	6,070	485	116	28,262	10,138	2,247	141	234	76	495	.245	.318	.404	.723
22	Rangers	336	410	.450	746	25,114	3,243	6,039	1,125	90	869	3,089	2,238	249	6,366	489	137	27,821	9,951	2,084	46	174	64	451	.240	.307	.396	.703
23	Royals	330	417	.442	747	24,994	3,124	6,146	1,186	157	729	2,998	1,996	257	5,893	609	178	27,582	9,833	2,072	103	232	57	437	.246	.306	.393	.699
24	Angels	327	417	.440	744	24,912	3,149	5,930	1,101	106	912	3,011	2,234	318	6,714	401	148	27,705	9,979	2,119	84	157	107	507	.238	.307	.401	.708
25	Marlins	327	417	.440	744	24,935	2,932	6,035	1,118	97	710	2,788	2,016	275	6,538	521	147	27,484	9,477	1,925	95	163	81	547	.242	.304	.380	.684