Since 2022, the Los Angeles Dodgers have the most wins by a team, with 333 wins.

Interpreted as:

most regular-season wins by an MLB team since 2022

	TEAM	W	L	W%	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Dodgers	333	188	.639	521	17,748	2,784	4,567	977	84	750	2,686	1,981	217	4,362	365	72	20,149	7,962	1,811	19	184	87	306	.257	.336	.449	.785
2	Braves	310	210	.596	520	17,730	2,579	4,546	913	52	803	2,476	1,610	200	4,533	310	83	19,676	7,972	1,768	14	122	44	371	.256	.323	.450	.773
3	Astros	301	218	.580	519	17,632	2,437	4,504	872	55	655	2,341	1,630	212	3,865	304	85	19,651	7,451	1,582	40	137	68	399	.255	.324	.423	.746
4	Yankees	294	227	.564	521	17,378	2,485	4,175	749	43	768	2,380	1,988	184	4,461	315	99	19,732	7,314	1,560	37	145	85	400	.240	.322	.421	.743
5	Phillies	291	229	.560	520	17,725	2,486	4,527	883	88	657	2,389	1,666	195	4,486	424	90	19,754	7,557	1,628	34	134	64	358	.255	.324	.426	.750
6	Brewers	289	233	.554	522	17,470	2,400	4,207	804	70	590	2,291	1,889	200	4,619	486	111	19,721	6,921	1,464	42	120	65	379	.241	.320	.396	.716
7	Orioles	288	231	.555	519	17,562	2,396	4,314	887	90	631	2,299	1,570	209	4,401	325	86	19,524	7,274	1,608	39	144	40	306	.246	.313	.414	.727
8	Mets	288	234	.552	522	17,569	2,430	4,360	839	72	633	2,328	1,684	332	4,194	308	64	19,766	7,242	1,544	50	131	53	363	.248	.323	.412	.736
9	Padres	287	233	.552	520	17,502	2,354	4,375	858	53	577	2,253	1,795	187	3,948	338	91	19,690	7,070	1,488	76	130	62	386	.250	.324	.404	.728
10	Mariners	283	236	.545	519	17,318	2,292	4,037	782	46	641	2,193	1,857	336	4,904	379	97	19,667	6,834	1,469	33	123	47	340	.233	.317	.395	.712
11	Rays	281	239	.540	520	17,453	2,261	4,246	875	67	544	2,151	1,616	238	4,586	474	137	19,441	6,887	1,486	23	111	35	317	.243	.314	.395	.709
12	Guardians	280	239	.539	519	17,483	2,199	4,308	855	80	474	2,078	1,496	235	3,734	443	117	19,426	6,745	1,409	57	155	111	353	.246	.312	.386	.698
13	Blue Jays	271	249	.521	520	17,655	2,312	4,461	936	58	567	2,216	1,668	218	4,022	262	93	19,695	7,214	1,561	32	122	49	414	.253	.323	.409	.731
14	Diamondbacks	265	256	.509	521	17,492	2,514	4,335	878	111	594	2,384	1,781	216	4,127	419	92	19,778	7,217	1,583	107	182	46	355	.248	.322	.413	.734
15	Cardinals	264	258	.506	522	17,748	2,330	4,447	881	55	606	2,233	1,712	220	4,143	315	90	19,855	7,256	1,542	38	137	46	355	.251	.322	.409	.731
16	Cubs	262	260	.502	522	17,636	2,429	4,342	852	99	579	2,315	1,763	241	4,489	440	108	19,836	7,129	1,530	56	140	49	329	.246	.321	.404	.725
17	Giants	262	260	.502	522	17,447	2,249	4,108	835	66	572	2,152	1,733	237	4,714	211	62	19,600	6,791	1,473	37	146	50	358	.235	.311	.389	.700
18	Twins	262	259	.503	521	17,617	2,349	4,318	903	69	622	2,242	1,686	276	4,593	209	66	19,744	7,225	1,594	32	133	40	388	.245	.319	.410	.729
19	Red Sox	255	267	.489	522	17,926	2,437	4,586	1,072	66	573	2,332	1,590	222	4,643	351	97	19,904	7,509	1,711	32	134	77	376	.256	.322	.419	.741
20	Rangers	253	268	.486	521	17,668	2,384	4,336	816	57	638	2,278	1,627	165	4,420	332	94	19,611	7,180	1,511	28	123	51	303	.245	.313	.406	.719
21	Tigers	252	269	.484	521	17,481	2,079	4,107	770	109	484	1,995	1,489	174	4,659	223	73	19,300	6,547	1,363	31	125	33	324	.235	.299	.375	.674
22	Reds	239	283	.458	522	17,410	2,306	4,159	814	87	565	2,197	1,637	286	4,694	493	138	19,496	6,842	1,466	51	112	24	333	.239	.313	.393	.706
23	Marlins	228	292	.438	520	17,587	2,040	4,303	807	69	491	1,941	1,368	185	4,425	361	103	19,321	6,721	1,367	58	123	49	413	.245	.304	.382	.686
24	Royals	227	295	.435	522	17,476	2,174	4,277	831	120	496	2,098	1,397	183	4,098	432	125	19,287	6,836	1,447	62	169	46	307	.245	.305	.391	.696
25	Pirates	226	296	.433	522	17,406	2,065	4,028	787	83	503	1,975	1,648	187	4,770	351	101	19,431	6,490	1,373	61	129	42	324	.231	.303	.373	.676