The San Diego Padres have an 85-74 record against the Mets since 2000.

	OPP	REC	W%	G	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Mets	85-74	.535	159	85	74	5,310	649	1,335	267	28	145	617	511	42	1,220	98	44	5,958	2,093	440	58	37	27	121	.251	.320	.394	.714
2	Nationals	88-69	.561	157	88	69	5,359	711	1,360	249	28	160	680	492	56	1,172	95	38	5,998	2,145	437	55	36	41	109	.254	.321	.400	.721
3	Diamondbacks	214-228	.484	442	214	228	14,872	1,909	3,657	715	82	468	1,813	1,421	146	3,508	232	97	16,661	5,940	1,265	110	112	80	307	.246	.316	.399	.715
4	Astros	62-54	.534	116	62	54	3,931	527	1,012	222	19	107	507	373	44	848	68	25	4,409	1,593	348	33	28	19	78	.257	.327	.405	.732
5	Cardinals	60-98	.380	158	60	98	5,293	603	1,318	261	25	135	575	512	46	1,117	64	24	5,944	2,034	421	53	40	32	129	.249	.318	.384	.703
6	Pirates	91-68	.572	159	91	68	5,356	734	1,370	266	28	147	698	595	65	1,137	121	36	6,130	2,133	441	58	56	33	137	.256	.334	.398	.733
7	Braves	77-94	.450	171	77	94	5,809	694	1,472	268	34	159	662	532	47	1,343	138	31	6,492	2,285	461	57	47	38	127	.253	.319	.393	.712
8	Marlins	86-76	.531	162	86	76	5,390	681	1,326	263	41	132	639	589	47	1,249	114	49	6,132	2,067	436	55	51	51	105	.246	.323	.383	.706
9	Reds	89-67	.571	156	89	67	5,350	747	1,367	273	25	185	714	531	50	1,210	90	30	6,031	2,245	483	52	48	39	104	.256	.326	.420	.745
10	Brewers	80-83	.491	163	80	83	5,538	703	1,419	243	31	161	664	570	34	1,278	120	40	6,235	2,207	435	52	41	43	130	.256	.327	.399	.726
11	Mariners	54-66	.450	120	54	66	3,990	466	945	169	20	115	439	350	31	913	57	27	4,423	1,499	304	28	24	17	71	.237	.302	.376	.677
12	Athletics	18-21	.462	39	18	21	1,335	165	333	54	5	44	151	132	12	318	24	12	1,497	529	103	10	8	9	29	.249	.321	.396	.717
13	Dodgers	184-256	.418	440	184	256	14,576	1,564	3,264	613	56	361	1,476	1,393	119	3,738	301	91	16,328	5,072	1,030	141	99	113	300	.224	.295	.348	.643
14	Rockies	213-235	.475	448	213	235	15,266	2,173	4,023	824	108	492	2,075	1,562	146	3,214	262	96	17,228	6,539	1,424	126	128	94	395	.264	.335	.428	.763
15	Rangers	25-19	.568	44	25	19	1,507	187	406	73	7	46	180	132	13	311	29	7	1,673	631	126	10	11	3	38	.269	.331	.419	.750
16	Angels	16-22	.421	38	16	22	1,270	150	293	55	6	29	137	142	16	308	25	11	1,454	447	90	15	11	13	21	.231	.313	.352	.665
17	Giants	213-229	.482	442	213	229	15,028	1,801	3,690	725	95	387	1,729	1,453	122	3,335	270	104	16,867	5,766	1,207	138	126	97	304	.246	.315	.384	.698
18	Phillies	59-98	.376	157	59	98	5,348	626	1,296	252	27	143	587	493	43	1,205	99	28	5,951	2,031	422	36	31	32	110	.242	.310	.380	.689
19	Cubs	88-80	.524	168	88	80	5,642	716	1,360	247	29	160	679	614	59	1,397	115	30	6,407	2,145	436	45	47	34	110	.241	.320	.380	.700
20	Rays	11-19	.367	30	11	19	991	122	231	45	2	31	115	113	12	248	23	9	1,130	373	78	5	9	7	22	.233	.316	.376	.693
21	Orioles	14-13	.519	27	14	13	944	153	267	50	4	40	144	85	14	204	24	7	1,051	445	94	6	2	3	25	.283	.350	.471	.822
22	Red Sox	10-17	.370	27	10	17	883	87	197	43	2	21	84	77	11	209	11	6	980	307	66	7	2	1	12	.223	.293	.348	.641
23	Yankees	10-17	.370	27	10	17	899	96	205	39	2	21	91	90	11	240	18	5	1,011	311	62	2	9	4	10	.228	.303	.346	.649
24	Royals	14-10	.583	24	14	10	833	128	243	41	5	27	121	93	6	181	5	9	947	375	73	5	10	8	22	.292	.363	.450	.813
25	Tigers	12-15	.444	27	12	15	883	108	210	42	6	24	105	91	10	187	11	6	999	336	72	10	5	5	25	.238	.314	.381	.695