Spencer Strider struck out the most batters in a game in 2022, with 16 strikeouts against the Rockies on September 1, 2022.

Interpreted as:

pitcher most k in a regular-season game 2022

	NAME	SO	DATE	TM		OPP	DEC	GS	ERA	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP
1	Spencer Strider S. Strider	16	9/1/2022	ATL	vs	COL	W	1	0.00	0	0	0	8.0	2	0	0	0	0	0	0	0	27	0
2	Corbin Burnes C. Burnes	14	9/8/2022	MIL	vs	SFG	W	1	1.13	0	0	0	8.0	3	1	1	0	0	1	0	0	27	0
3	Gerrit Cole G. Cole	14	9/7/2022	NYY	vs	MIN	W	1	1.35	0	0	0	6.2	5	1	1	1	2	0	0	0	27	0
4	Triston McKenzie T. McKenzie	14	8/19/2022	CLE	vs	CWS	W	1	2.57	0	0	0	7.0	6	2	2	0	0	0	0	0	26	1
5	Cristian Javier C. Javier	14	7/1/2022	HOU	vs	LAA	W	1	1.29	0	0	0	7.0	1	1	1	1	0	0	0	0	22	0
6	Sandy Alcantara S. Alcantara	14	5/28/2022	MIA	@	ATL	W	1	1.13	0	0	0	8.0	4	1	1	0	0	1	0	0	26	0
7	Zac Gallen Z. Gallen	13	9/22/2022	ARI	@	LAD		1	1.13	0	0	0	8.0	2	1	1	0	0	0	0	0	26	0
8	Triston McKenzie T. McKenzie	13	9/21/2022	CLE	@	CWS	W	1	2.25	0	0	0	8.0	6	2	2	1	0	0	0	0	30	0
9	Blake Snell B. Snell	13	9/21/2022	SDP	vs	STL	W	1	0.00	0	0	0	7.0	2	0	0	0	2	0	0	0	25	0
10	Jacob deGrom J. deGrom	13	9/18/2022	NYM	vs	PIT		1	5.40	0	0	0	5.0	4	3	3	1	0	0	0	0	19	0
11	Spencer Strider S. Strider	13	8/2/2022	ATL	vs	PHI	W	1	1.35	0	0	0	6.2	3	1	1	0	1	0	0	0	24	0
12	José Berríos J. Berríos	13	7/12/2022	TOR	vs	PHI	W	1	4.50	0	0	0	6.0	6	3	3	1	0	0	0	0	25	0
13	Framber Valdez F. Valdez	13	7/3/2022	HOU	vs	LAA		1	3.00	0	0	0	6.0	4	2	2	1	5	0	0	0	26	0
14	Dylan Cease D. Cease	13	6/26/2022	CWS	vs	BAL	W	1	1.29	0	0	0	7.0	4	1	1	1	1	0	0	0	26	0
15	Cristian Javier C. Javier	13	6/25/2022	HOU	@	NYY	W	1	0.00	0	0	0	7.0	0	0	0	0	1	0	0	0	23	0
16	Shohei Ohtani S. Ohtani	13	6/22/2022	LAA	vs	KCR	W	1	0.00	0	0	0	8.0	2	0	0	0	1	0	0	0	26	0
17	José Berríos J. Berríos	13	6/4/2022	TOR	vs	MIN	W	1	2.57	0	0	0	7.0	3	2	2	1	2	1	0	0	26	0
18	Eric Lauer E. Lauer	13	4/24/2022	MIL	@	PHI		1	0.00	0	0	0	6.0	5	0	0	0	1	0	0	0	24	0
19	Clayton Kershaw C. Kershaw	13	4/13/2022	LAD	@	MIN	W	1	0.00	0	0	0	7.0	0	0	0	0	0	0	0	0	21	0
20	Jesús Luzardo J. Luzardo	12	10/3/2022	MIA	vs	ATL	W	1	0.00	0	0	0	6.0	4	0	0	0	1	0	0	0	23	0
21	Nestor Cortes N. Cortes	12	10/1/2022	NYY	vs	BAL	W	1	0.00	0	0	0	7.1	1	0	0	0	2	0	0	0	24	0
22	Zac Gallen Z. Gallen	12	8/18/2022	ARI	@	SFG	W	1	0.00	0	0	0	7.1	4	0	0	0	0	0	0	0	25	0
23	Charlie Morton C. Morton	12	8/16/2022	ATL	vs	NYM	W	1	0.00	0	0	0	6.2	3	0	0	0	1	0	0	0	23	0
24	Jacob deGrom J. deGrom	12	8/7/2022	NYM	vs	ATL	W	1	3.18	0	0	0	5.2	1	2	2	1	1	0	0	0	19	0
25	Reid Detmers R. Detmers	12	7/31/2022	LAA	vs	TEX		1	1.29	0	0	0	7.0	3	1	2	0	3	0	0	0	25	0