pitcher most strikeouts vs minnesota twins

Nolan Ryan has fanned the most hitters in a season versus the Twins, with 65 strikeouts in 1973.

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Regular season

	NAME	SO	SEASON	TM	G	W	L	W%	GS	ERA	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Nolan Ryan N. Ryan	65	1973	CAL	5	4	1	.800	5	3.26	5	0	0	47.0	39	17	18	2	28	0	0	0	201	2	12.45	5.36	2.32	0.38	32.3	13.9	1.43	.349	3.45	7.47
2	Bob Feller B. Feller	59	1946	CLE	7	5	1	.833	6	1.32	6	2	0	54.2	33	8	10	1	19	2	1		215	0	9.71	3.13	3.11	0.16	27.4	8.8	0.95	.239	1.65	5.43
3	Rube Waddell R. Waddell	56	1908	SLA	8	4	2	.667	6		4	0	1	50.1	34		16	0	19	0	2		198	2	10.01	3.40	2.95	0.00	28.3	9.6	1.05	.276	2.86	6.08
4	Luis Tiant L. Tiant	55	1968	CLE	5	4	0	1.000	5	1.15	3	2	0	39.0	20	5	5	3	8	0	0	0	141	0	12.69	1.85	6.88	0.69	39.0	5.7	0.72	.227	1.15	4.62
5	Frank Smith F. Smith	54	1905	CWS	10	5	4	.556	8		6	2	0	67.1	36		17	0	23	1	1			4	7.22	3.07	2.35	0.00		11.7	0.88	.303	2.27	4.81
6	Herb Score H. Score	52	1956	CLE	5	4	0	1.000	5	2.00	4	2	0	36.0	18	8	8	4	29	0	0	0	153	1	13.00	7.25	1.79	1.00	34.0	19.0	1.31	.206	2.00	4.50
7	Earl Hamilton E. Hamilton	50	1912	SLA	7	2	2	.500	4	0.00	4	1	0	53.2	40		20	0	17	1	3		214	1	8.39	2.85	2.94	0.00	23.4	7.9	1.06	.274	3.35	6.71
8	Jim Bunning J. Bunning	49	1959	DET	7	3	3	.500	7	3.13	4	0	0	54.2	43	19	20	6	19	1	0	0	223	0	8.07	3.13	2.58	0.99	22.0	8.5	1.13	.250	3.29	7.08
9	Frank Smith F. Smith	47	1904	CWS	10	9	1	.900	9	0.78	9	3	0	81.0	53	7	7	0	15	4	1			3	5.22	1.67	3.13	0.00		4.9	0.84	.222	0.78	5.89
10	Rube Waddell R. Waddell	47	1904	PHA	7	5	1	.833	7	1.06	6	1	0	51.0	39	6	17	0	11	3	0			2	8.29	1.94	4.27	0.00		5.5	0.98	.281	3.00	6.88
11	Paul Foytack P. Foytack	46	1956	DET	8	4	2	.667	8	4.64	4	0	0	54.1	47	28	29	7	28	0	0	0	228	2	7.62	4.64	1.64	1.16	20.2	12.3	1.38	.272	4.80	7.79
12	Cy Young C. Young	46	1905	BSA	6	4	2	.667	5		5	2	0	45.0	28		6	0	3	2	1			1	9.20	0.60	15.33	0.00		1.9	0.69	.252	1.20	5.60
13	Chris Sale C. Sale	45	2015	CWS	6	1	4	.200	6	7.36	0	0	0	33.0	46	27	30	4	6	1	0	0	152	3	12.27	1.64	7.50	1.09	29.6	3.9	1.58	.438	8.18	12.55
14	Nolan Ryan N. Ryan	45	1974	CAL	5	3	2	.600	4	1.72	4	1	0	36.2	19	7	13	3	24	1	1	0	153	1	11.05	5.89	1.88	0.74	29.4	15.7	1.17	.200	3.19	4.66
15	Vida Blue V. Blue	45	1971	OAK	5	2	2	.500	5	2.16	3	0	0	41.2	31	10	14	5	18	0	0	0	168	3	9.72	3.89	2.50	1.08	26.8	10.7	1.18	.260	3.02	6.70
16	Fred Glade F. Glade	44	1904	SLA	9	5	3	.625	8	2.58	8	2	1	69.2	55	20	27	1	11	6	1			0	5.68	1.42	4.00	0.13		4.0	0.95	.250	3.49	7.11
17	Nolan Ryan N. Ryan	43	1972	CAL	4	3	1	.750	4	1.97	3	1	0	32.0	20	7	7	0	17	1	0	0	128	2	12.09	4.78	2.53	0.00	33.6	13.3	1.16	.299	1.97	5.63
18	Denny McLain D. McLain	43	1968	DET	6	6	0	1.000	6	1.47	6	0	0	55.0	36	9	11	4	10	1	0	0	208	0	7.04	1.64	4.30	0.65	20.7	4.8	0.84	.213	1.80	5.89
19	Jack Harshman J. Harshman	42	1958	BAL	8	4	2	.667	6	1.73	4	1	1	57.1	45	11	13	3	22	1	2	0	241	2	6.59	3.45	1.91	0.47	17.4	9.1	1.17	.243	2.04	7.06
20	Early Wynn E. Wynn	41	1954	CLE	6	5	1	.833	6	2.61	3	0	0	48.1	34	14	16	5	19	0	0		197	1	7.63	3.54	2.16	0.93	20.8	9.6	1.10	.220	2.98	6.33
21	Carlos Carrasco C. Carrasco	40	2018	CLE	6	2	3	.400	6	3.51	0	0	0	33.1	32	13	13	2	8	2	0	1	139	0	10.80	2.16	5.00	0.54	28.8	5.8	1.20	.345	3.51	8.64
22	Billy Hoeft B. Hoeft	40	1956	DET	6	4	1	.800	5	1.83	4	2	0	44.1	39	9	11	5	22	0	0	1	192	0	8.12	4.47	1.82	1.02	20.8	11.5	1.38	.272	2.23	7.92
23	Lefty Grove L. Grove	40	1931	PHA	8	6	1	.857	6	2.25	5	0	0	56.0	62	14	21	1	9	0	1		243	0	6.43	1.45	4.44	0.16	16.5	3.7	1.27	.316	3.38	9.96
24	Rube Waddell R. Waddell	40	1903	PHA	6	4	1	.800	6	2.16	5	2	0	50.0	36	12	13	0	9	2	0			2	7.20	1.62	4.44	0.00		5.4	0.90	.313	2.34	6.48
25	Javier Vazquez J. Vazquez	39	2007	CWS	5	3	0	1.000	5	2.52	1	0	0	35.2	29	10	10	3	8	1	0	0	139	0	9.84	2.02	4.88	0.76	28.1	5.8	1.04	.295	2.52	7.32

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Some of the information used here was obtained free of charge from Retrosheet.

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Padres - w	91	71	.562	9.0
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Nolan Ryan has fanned the most hitters in a season versus the Twins, with 65 strikeouts in 1973.

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