Since 2020, Patrick Corbin has lost the most games, with 72 games.

Interpreted as:

pitcher with most regular-season loses since 2020

	NAME	L	W	L%	G	W%	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Patrick Corbin P. Corbin	72	35	.673	143	.327	143	5.52	614	1	0	0	776.1	937	476	506	136	250	17	0	5	3,447	14	7.12	2.90	2.46	1.58	17.8	7.3	1.53	.330	5.87	132	4.90	116	10.86	-56.1
2	Luis Castillo L. Castillo	52	47	.525	141	.475	141	3.51	875	1	0	0	823.2	721	321	354	94	265	27	0	6	3,420	5	9.56	2.90	3.30	1.03	25.6	7.7	1.20	.290	3.87	86	3.59	87	7.88	51.1
3	Aaron Nola A. Nola	50	52	.490	149	.510	149	3.95	1,003	6	4	0	896.0	801	393	416	124	201	27	0	4	3,654	8	10.07	2.02	4.99	1.25	27.4	5.5	1.12	.294	4.18	94	3.49	82	8.05	75.8
4	Kyle Freeland K. Freeland	49	28	.636	125	.364	125	4.82	491	0	0	0	674.1	782	361	392	102	189	26	0	1	2,934	8	6.55	2.52	2.60	1.36	16.7	6.4	1.44	.320	5.23	100	4.63	105	10.44	-15.4
5	Mitch Keller M. Keller	49	36	.576	130	.424	128	4.41	657	2	1	0	698.2	719	342	364	79	247	51	0	2	3,041	13	8.46	3.18	2.66	1.02	21.6	8.1	1.38	.319	4.69	103	4.04	97	9.26	10
6	Jordan Lyles J. Lyles	47	29	.618	112	.382	102	5.41	449	4	0	0	599.1	635	360	377	115	178	23	4	0	2,576	27	6.74	2.67	2.52	1.73	17.4	6.9	1.36	.287	5.66	126	5.18	122	9.54	-63
7	Brady Singer B. Singer	46	40	.535	134	.465	131	4.25	683	1	0	0	724.2	726	342	366	87	228	43	2	1	3,096	16	8.48	2.83	3.00	1.08	22.1	7.4	1.32	.311	4.55	98	3.97	95	9.02	15.1
8	José Berríos J. Berríos	44	57	.436	148	.564	148	3.97	803	2	0	0	855.2	801	377	395	123	243	52	0	5	3,571	17	8.45	2.56	3.30	1.29	22.5	6.8	1.22	.289	4.15	97	4.19	101	8.43	-2
9	Charlie Morton C. Morton	43	47	.478	142	.522	139	4.14	841	0	0	0	756.0	676	348	372	93	301	71	0	4	3,232	16	10.01	3.58	2.79	1.11	26.0	9.3	1.29	.303	4.43	99	4.02	98	8.05	6.9
10	Miles Mikolas M. Mikolas	42	34	.553	116	.447	115	4.43	461	1	0	0	654.0	667	322	340	84	126	23	0	0	2,719	6	6.34	1.73	3.66	1.16	17.0	4.6	1.21	.288	4.68	108	4.11	101	9.18	-4.3
11	Sandy Alcantara S. Alcantara	42	35	.545	107	.455	107	3.37	621	10	2	0	692.0	588	259	294	69	181	25	0	3	2,799	18	8.08	2.35	3.43	0.90	22.2	6.5	1.11	.273	3.82	79	3.56	86	7.65	44.9
12	Kevin Gausman K. Gausman	42	58	.420	146	.580	144	3.34	950	2	1	0	837.2	748	311	343	86	217	10	1	2	3,439	19	10.21	2.33	4.38	0.92	27.6	6.3	1.15	.304	3.69	83	3.05	74	8.04	100.4
13	Kyle Hendricks K. Hendricks	42	35	.545	120	.455	115	4.58	462	2	1	0	650.0	673	331	349	96	161	26	4	4	2,749	3	6.40	2.23	2.87	1.33	16.8	5.9	1.28	.288	4.83	111	4.53	109	9.32	-27.2
14	Nick Pivetta N. Pivetta	42	42	.500	141	.500	114	4.25	766	1	0	2	679.0	594	321	332	109	242	18	4	4	2,842	29	10.15	3.21	3.17	1.44	27.0	8.5	1.23	.284	4.40	98	4.14	99	7.87	2.7
15	Dylan Cease D. Cease	41	54	.432	150	.568	150	3.62	983	3	3	0	814.2	664	328	364	89	341	29	0	7	3,434	46	10.86	3.77	2.88	0.98	28.6	9.9	1.23	.289	4.02	87	3.54	83	7.34	64.1
16	Kyle Gibson K. Gibson	41	44	.482	139	.518	138	4.60	670	1	1	0	786.1	782	402	424	105	268	33	0	4	3,344	20	7.67	3.07	2.50	1.20	20.0	8.0	1.34	.299	4.85	111	4.35	104	8.95	-14.2
17	Patrick Sandoval P. Sandoval	41	19	.683	97	.317	91	4.00	487	1	1	1	496.2	476	221	258	49	217	16	2	4	2,165	22	8.82	3.93	2.24	0.89	22.5	10.0	1.40	.306	4.68	95	3.90	91	8.63	20.1
18	Tyler Anderson T. Anderson	40	44	.476	139	.524	133	3.96	608	1	0	0	766.0	704	337	362	97	249	29	0	7	3,228	19	7.14	2.93	2.44	1.14	18.8	7.7	1.24	.270	4.25	95	4.31	102	8.27	-8.4
19	Yusei Kikuchi Y. Kikuchi	40	35	.533	142	.467	130	4.32	760	0	0	1	690.1	653	331	358	111	252	21	4	1	2,935	25	9.91	3.29	3.02	1.45	25.9	8.6	1.31	.303	4.67	106	4.25	102	8.51	-6.9
20	Marcus Stroman M. Stroman	39	36	.520	118	.480	115	3.78	516	1	1	1	618.1	583	260	292	63	199	22	2	2	2,596	14	7.51	2.90	2.59	0.92	19.9	7.7	1.26	.290	4.25	93	3.90	94	8.49	19
21	Chris Bassitt C. Bassitt	39	61	.390	140	.610	140	3.47	784	2	2	0	818.2	746	316	341	92	242	56	0	5	3,423	20	8.62	2.66	3.24	1.01	22.9	7.1	1.21	.291	3.75	86	3.81	92	8.20	29.7
22	Andrew Heaney A. Heaney	39	33	.542	131	.458	115	4.38	674	0	0	0	616.0	586	300	326	102	193	41	4	2	2,643	11	9.85	2.82	3.49	1.49	25.5	7.3	1.26	.296	4.76	104	4.28	100	8.56	0
23	Cole Irvin C. Irvin	39	26	.600	118	.400	90	4.44	403	0	0	1	551.1	590	272	301	78	129	29	11	4	2,359	10	6.58	2.11	3.12	1.27	17.1	5.5	1.30	.298	4.91	112	4.39	109	9.63	-23.9
24	Pablo López P. López	39	50	.438	133	.562	133	3.64	817	1	1	0	752.1	678	304	324	88	191	34	0	4	3,097	17	9.77	2.28	4.28	1.05	26.4	6.2	1.16	.300	3.88	88	3.42	83	8.11	59.2
25	Logan Webb L. Webb	39	56	.411	146	.589	143	3.29	789	3	2	0	864.0	811	316	348	56	203	29	0	4	3,515	17	8.22	2.11	3.89	0.58	22.4	5.8	1.17	.310	3.63	81	2.99	75	8.45	100.2