Since 2016, Patrick Corbin has lost the most games, with 117 games.

Interpreted as:

pitcher with most regular-season losses since 2016

	NAME	L	W	L%	G	W%	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Patrick Corbin P. Corbin	117	81	.591	287	.409	274	4.69	1,452	4	2	1	1574.1	1,704	821	891	233	507	34	6	20	6,821	46	8.30	2.90	2.86	1.33	21.3	7.4	1.40	.320	5.09	111	4.27	101	9.74	-4.3
2	Kevin Gausman K. Gausman	89	94	.486	281	.514	265	3.80	1,618	2	1	0	1543.2	1,490	651	700	192	434	35	7	7	6,465	43	9.43	2.53	3.73	1.12	25.0	6.7	1.25	.310	4.08	91	3.59	84	8.69	112.4
3	Kyle Gibson K. Gibson	84	85	.497	261	.503	255	4.65	1,239	2	1	0	1453.0	1,504	750	804	196	522	54	0	9	6,253	50	7.67	3.23	2.37	1.21	19.8	8.3	1.39	.308	4.98	109	4.40	103	9.32	-20.5
4	Aaron Nola A. Nola	84	99	.459	264	.541	264	3.78	1,763	6	4	0	1593.1	1,408	670	708	199	418	53	0	15	6,537	18	9.96	2.36	4.22	1.12	27.0	6.4	1.15	.295	4.00	90	3.46	80	7.95	146
5	Kyle Freeland K. Freeland	82	60	.577	220	.423	215	4.55	879	0	0	0	1175.1	1,307	594	645	167	372	43	0	11	5,106	16	6.73	2.85	2.36	1.28	17.2	7.3	1.43	.313	4.94	95	4.57	103	10.01	-17.3
6	Luis Castillo L. Castillo	81	76	.516	228	.484	228	3.56	1,410	1	0	0	1326.1	1,132	524	572	163	439	43	0	8	5,486	17	9.57	2.98	3.21	1.11	25.7	8.0	1.18	.282	3.88	86	3.73	88	7.68	73.3
7	José Berríos J. Berríos	80	103	.437	261	.563	260	4.02	1,432	5	1	0	1507.2	1,400	673	717	205	454	95	0	7	6,324	35	8.55	2.71	3.15	1.22	22.6	7.2	1.23	.289	4.28	95	4.12	97	8.36	23.2
8	Marcus Stroman M. Stroman	80	73	.523	235	.477	232	3.82	1,083	3	1	1	1315.0	1,294	558	624	133	411	35	2	4	5,527	36	7.41	2.81	2.64	0.91	19.6	7.4	1.30	.300	4.27	91	3.85	90	8.86	62.4
9	Kyle Hendricks K. Hendricks	78	87	.473	247	.527	241	3.78	1,105	5	3	0	1407.0	1,353	591	638	178	329	56	4	16	5,829	9	7.07	2.10	3.36	1.14	19.0	5.6	1.20	.282	4.08	91	4.06	97	8.65	20.1
10	Sonny Gray S. Gray	77	85	.475	248	.525	241	3.74	1,412	2	1	0	1346.1	1,176	559	607	141	448	48	2	3	5,608	75	9.44	2.99	3.15	0.94	25.2	8.0	1.21	.291	4.06	88	3.53	83	7.86	108.3
11	Nick Pivetta N. Pivetta	73	65	.529	240	.471	195	4.63	1,246	2	0	3	1126.1	1,055	579	605	187	401	32	13	6	4,771	52	9.96	3.20	3.11	1.49	26.1	8.4	1.29	.299	4.83	108	4.26	101	8.43	-3.3
12	José Ureña J. Ureña	72	43	.626	221	.374	145	4.74	617	1	0	6	905.0	925	477	513	129	334	46	29	24	3,918	22	6.14	3.32	1.85	1.28	15.7	8.5	1.39	.285	5.10	114	4.91	118	9.20	-76.7
13	Jose Quintana J. Quintana	71	75	.486	248	.514	225	3.88	1,168	1	1	0	1286.2	1,236	555	597	144	424	36	5	10	5,422	51	8.17	2.97	2.75	1.01	21.5	7.8	1.29	.299	4.18	93	3.87	93	8.65	46.1
14	Tyler Anderson T. Anderson	69	62	.527	222	.473	214	4.25	1,018	1	0	0	1214.1	1,170	574	614	171	393	39	1	12	5,146	41	7.54	2.91	2.59	1.27	19.8	7.6	1.29	.283	4.55	97	4.38	102	8.67	-13
15	Jordan Lyles J. Lyles	69	49	.585	253	.415	148	5.30	766	4	0	1	956.1	1,014	563	598	172	311	35	33	8	4,143	45	7.21	2.93	2.46	1.62	18.5	7.5	1.39	.295	5.63	122	4.99	117	9.54	-76.5
16	Martín Pérez M. Pérez	69	73	.486	264	.514	225	4.47	935	1	1	0	1303.1	1,410	648	716	162	484	43	12	8	5,673	27	6.46	3.34	1.93	1.12	16.5	8.5	1.45	.308	4.94	100	4.56	105	9.74	-29.3
17	Jon Gray J. Gray	68	72	.486	219	.514	214	4.42	1,171	2	1	0	1176.0	1,139	577	615	151	387	49	3	11	4,987	41	8.96	2.96	3.03	1.16	23.5	7.8	1.30	.306	4.71	97	3.96	90	8.72	54.9
18	Carlos Carrasco C. Carrasco	67	79	.459	214	.541	199	4.23	1,167	5	2	1	1117.2	1,113	525	555	162	306	42	6	11	4,690	45	9.40	2.46	3.81	1.30	24.9	6.5	1.27	.316	4.47	100	3.89	92	8.96	44.6
19	Zach Eflin Z. Eflin	67	68	.496	198	.504	186	4.27	914	5	3	1	1064.1	1,096	505	544	160	219	32	5	14	4,461	14	7.73	1.85	4.17	1.35	20.5	4.9	1.24	.298	4.60	103	4.12	97	9.27	14.6
20	Matthew Boyd M. Boyd	66	53	.555	186	.445	173	4.45	935	2	1	0	949.2	913	470	504	150	296	48	2	7	4,038	27	8.86	2.81	3.16	1.42	23.2	7.3	1.27	.292	4.78	103	4.33	100	8.65	-2.1
21	Madison Bumgarner M. Bumgarner	66	49	.574	175	.426	175	3.97	940	6	2	0	1038.1	974	458	500	153	276	53	0	13	4,348	14	8.15	2.39	3.41	1.33	21.6	6.3	1.20	.281	4.33	96	4.21	104	8.44	-23.5
22	Dylan Bundy D. Bundy	65	54	.546	188	.454	162	4.75	852	3	1	0	909.0	901	480	515	163	284	38	7	6	3,881	19	8.44	2.81	3.00	1.61	22.0	7.3	1.30	.290	5.10	110	4.68	106	8.92	-22.9
23	Germán Márquez G. Márquez	65	68	.489	194	.511	191	4.51	1,047	4	2	0	1103.1	1,113	553	600	152	333	37	0	13	4,700	59	8.54	2.72	3.14	1.24	22.3	7.1	1.31	.307	4.89	94	4.05	92	9.08	45.8
24	Trevor Williams T. Williams	65	53	.551	219	.449	178	4.46	825	1	1	1	1009.0	1,065	500	543	146	323	38	10	12	4,361	11	7.36	2.88	2.55	1.30	18.9	7.4	1.38	.303	4.84	106	4.49	105	9.50	-28.2
25	Miles Mikolas M. Mikolas	63	64	.496	189	.504	188	4.10	789	3	2	0	1086.0	1,099	495	526	135	195	42	0	5	4,491	14	6.54	1.62	4.05	1.12	17.6	4.3	1.19	.289	4.36	101	3.98	98	9.11	10.7