Since 2021, Dylan Cease has struck out the most hitters, with 1,020 strikeouts.

	NAME	SO	G	W	L	W%	GS	ERA	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Dylan Cease D. Cease	1,020	149	51	44	.537	149	3.69	3	3	0	819.1	672	336	369	88	329	26	0	6	3,446	47	11.20	3.61	3.10	0.97	29.6	9.5	1.22	.295	4.05	89	3.36	80	7.38	75.5
2	Zack Wheeler Z. Wheeler	1,000	141	64	33	.660	141	2.86	4	2	0	880.1	680	280	302	82	197	36	0	2	3,497	17	10.22	2.01	5.08	0.84	28.6	5.6	1.00	.274	3.09	68	2.89	68	6.95	129.9
3	Kevin Gausman K. Gausman	935	145	58	43	.574	145	3.40	2	1	0	842.1	759	318	349	88	223	13	0	2	3,470	15	9.99	2.38	4.19	0.94	26.9	6.4	1.17	.303	3.73	85	3.14	76	8.11	91.5
4	Corbin Burnes C. Burnes	921	136	51	32	.614	136	2.91	0	0	0	821.1	622	266	296	81	225	32	0	1	3,287	33	10.09	2.47	4.09	0.89	28.0	6.8	1.03	.267	3.24	70	3.14	76	6.82	92.2
5	Aaron Nola A. Nola	909	138	47	46	.505	138	4.09	4	3	0	828.1	759	376	394	118	179	25	0	2	3,389	7	9.88	1.94	5.08	1.28	26.8	5.3	1.13	.297	4.28	98	3.56	84	8.25	61.7
6	Charlie Morton C. Morton	859	144	50	41	.549	138	4.01	0	0	0	769.2	678	343	367	92	307	73	1	5	3,282	16	10.04	3.59	2.80	1.08	26.2	9.4	1.28	.300	4.29	96	3.96	97	7.93	10.8
7	Luis Castillo L. Castillo	846	140	46	48	.489	140	3.50	0	0	0	818.2	717	318	347	97	257	28	0	6	3,391	5	9.30	2.83	3.29	1.07	24.9	7.6	1.19	.287	3.81	87	3.68	90	7.88	38.2
8	Nick Pivetta N. Pivetta	827	148	44	43	.506	124	4.12	1	0	2	732.1	632	335	348	114	253	18	4	5	3,050	28	10.16	3.11	3.27	1.40	27.1	8.3	1.21	.282	4.28	96	4.03	97	7.77	10.4
9	Logan Webb L. Webb	826	145	58	39	.598	144	3.15	3	2	0	887.0	824	310	340	60	194	24	0	3	3,587	15	8.38	1.97	4.26	0.61	23.0	5.4	1.15	.308	3.45	78	2.91	73	8.36	108.2
10	Gerrit Cole G. Cole	821	113	52	25	.675	113	3.15	4	3	0	686.0	540	240	252	88	168	17	0	2	2,730	11	10.77	2.20	4.89	1.15	30.1	6.2	1.03	.276	3.31	78	3.26	77	7.08	73.5
11	Zac Gallen Z. Gallen	817	136	54	37	.593	136	3.70	2	2	0	778.1	663	320	340	90	242	29	0	2	3,200	25	9.45	2.80	3.38	1.04	25.5	7.6	1.16	.283	3.93	88	3.61	90	7.67	36.4
12	Carlos Rodón C. Rodón	816	121	56	36	.609	121	3.48	2	1	0	669.2	523	259	275	86	214	29	0	1	2,744	33	10.97	2.88	3.81	1.16	29.7	7.8	1.10	.273	3.70	85	3.46	82	7.03	54
13	Framber Valdez F. Valdez	813	131	65	34	.657	131	3.03	9	3	0	831.1	677	280	307	63	278	43	0	1	3,401	40	8.80	3.01	2.92	0.68	23.9	8.2	1.15	.279	3.32	75	3.34	82	7.33	69.1
14	Freddy Peralta F. Peralta	809	128	48	32	.600	126	3.35	1	0	0	673.1	493	251	263	84	242	37	0	1	2,758	22	10.81	3.23	3.34	1.12	29.3	8.8	1.09	.258	3.52	80	3.62	86	6.59	43.3
15	Logan Gilbert L. Gilbert	799	133	42	33	.560	133	3.59	2	1	0	765.1	648	305	325	100	165	20	0	6	3,091	34	9.40	1.94	4.84	1.18	25.8	5.3	1.06	.273	3.82	92	3.50	88	7.62	41.3
16	Yusei Kikuchi Y. Kikuchi	789	145	37	38	.493	133	4.10	0	0	1	714.0	676	325	358	116	261	21	4	3	3,038	23	9.95	3.29	3.02	1.46	26.0	8.6	1.31	.303	4.51	101	4.25	102	8.52	-7.4
17	José Berríos J. Berríos	787	148	56	43	.566	148	3.94	2	0	0	861.1	801	377	396	122	237	53	0	6	3,578	12	8.22	2.48	3.32	1.27	22.0	6.6	1.21	.285	4.14	97	4.18	101	8.37	-2.7
18	Chris Bassitt C. Bassitt	784	141	62	39	.614	140	3.66	3	2	0	817.0	757	332	356	93	246	61	0	5	3,430	19	8.64	2.71	3.19	1.02	22.9	7.2	1.23	.296	3.92	91	3.85	93	8.34	24.6
19	Pablo López P. López	782	127	46	36	.561	127	3.64	1	1	0	722.2	653	292	308	87	182	35	0	3	2,974	18	9.74	2.27	4.30	1.08	26.3	6.1	1.16	.300	3.84	88	3.47	85	8.13	51.3
20	Sonny Gray S. Gray	776	129	44	34	.564	129	3.46	1	1	0	713.1	610	274	293	69	199	26	0	1	2,920	26	9.79	2.51	3.90	0.87	26.6	6.8	1.13	.292	3.70	84	3.19	77	7.70	74.9
21	Tarik Skubal T. Skubal	764	117	50	30	.625	115	3.05	1	1	0	660.1	529	224	241	72	144	23	1	0	2,632	9	10.41	1.96	5.31	0.98	29.0	5.5	1.02	.281	3.28	75	3.01	73	7.21	79.7
22	Blake Snell B. Snell	724	105	35	28	.556	105	3.13	1	1	0	549.2	394	191	204	48	271	9	0	1	2,291	36	11.85	4.44	2.67	0.79	31.6	11.8	1.21	.279	3.34	79	3.21	77	6.45	56.9
23	Mitch Keller M. Keller	698	137	37	54	.407	135	4.30	2	1	0	751.0	771	359	384	81	241	51	0	2	3,248	12	8.36	2.89	2.90	0.97	21.5	7.4	1.35	.317	4.60	101	3.87	93	9.24	23.2
24	Nathan Eovaldi N. Eovaldi	690	122	48	28	.632	122	3.47	5	3	0	697.1	624	269	288	79	158	26	0	3	2,845	17	8.91	2.04	4.37	1.02	24.3	5.6	1.12	.288	3.72	82	3.45	82	8.05	59.6
25	Max Fried M. Fried	687	121	58	28	.674	121	2.79	5	4	0	725.0	607	225	251	56	175	27	0	2	2,914	30	8.53	2.17	3.93	0.70	23.6	6.0	1.08	.280	3.12	67	3.09	75	7.54	81.3