Cliff Lee and Brandon Webb were tied for winning the most games in 2008, with 22 wins.

	NAME	W	SEASON	TM	L	W%	G	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Cliff Lee C. Lee	22	2008	CLE	3	.880	31	31	2.54	170	4	2	0	223.1	214	63	68	12	34	5	0	1	891	4	6.85	1.37	5.00	0.48	19.1	3.8	1.11	.301	2.74	59	2.82	67	8.62	35.4
2	Brandon Webb B. Webb	22	2008	ARI	7	.759	34	34	3.30	183	3	1	0	226.2	206	83	95	13	65	12	0	5	944	8	7.27	2.58	2.82	0.52	19.4	6.9	1.20	.288	3.77	73	3.27	74	8.18	28
3	Roy Halladay R. Halladay	20	2008	TOR	11	.645	34	33	2.78	206	9	2	0	246.0	220	76	88	18	39	12	0	3	987	4	7.54	1.43	5.28	0.66	20.9	4.0	1.05	.284	3.22	64	3.02	69	8.05	36.3
4	Mike Mussina M. Mussina	20	2008	NYY	9	.690	34	34	3.37	150	0	0	0	200.1	214	75	85	17	31	8	0	3	819	4	6.74	1.39	4.84	0.76	18.3	3.8	1.22	.321	3.82	78	3.31	77	9.61	22.3
5	A.J. Burnett	18	2008	TOR	10	.643	35	34	4.07	231	1	0	0	221.1	211	100	109	19	86	9	1	2	957	11	9.39	3.50	2.69	0.77	24.1	9.0	1.34	.314	4.43	94	3.44	79	8.58	22.5
6	Tim Lincecum T. Lincecum	18	2008	SFG	5	.783	34	33	2.62	265	2	1	0	227.0	182	66	72	11	84	6	0	1	928	17	10.51	3.33	3.15	0.44	28.6	9.1	1.17	.304	2.85	61	2.61	62	7.22	41.5
7	Daisuke Matsuzaka D. Matsuzaka	18	2008	BOS	3	.857	29	29	2.90	154	0	0	0	167.2	128	54	58	12	94	7	0	1	716	5	8.27	5.05	1.64	0.64	21.5	13.1	1.32	.258	3.11	64	4.02	96	6.87	2.9
8	Ryan Dempster R. Dempster	17	2008	CHC	6	.739	33	33	2.96	187	1	0	0	206.2	174	68	75	14	76	7	0	1	856	5	8.14	3.31	2.46	0.61	21.8	8.9	1.21	.280	3.27	66	3.40	77	7.58	22.7
9	Gavin Floyd G. Floyd	17	2008	CWS	8	.680	33	33	3.84	145	1	0	0	206.1	190	88	107	30	70	9	0	6	878	9	6.32	3.05	2.07	1.31	16.5	8.0	1.26	.256	4.67	85	4.76	105	8.29	-4.5
10	Ted Lilly T. Lilly	17	2008	CHC	9	.654	34	34	4.09	184	0	0	0	204.2	187	93	96	32	64	7	0	2	861	4	8.09	2.81	2.88	1.41	21.4	7.4	1.23	.270	4.22	91	4.40	100	8.22	0.2
11	Roy Oswalt R. Oswalt	17	2008	HOU	10	.630	32	32	3.54	165	3	2	0	208.2	199	82	89	23	47	10	0	2	862	1	7.12	2.03	3.51	0.99	19.1	5.5	1.18	.285	3.84	84	3.79	87	8.58	13
12	CC Sabathia	17	2008	TOT	10	.630	35	35	2.70	251	10	5	0	253.0	223	76	85	19	59	7	0	1	1,023	2	8.93	2.10	4.25	0.68	24.5	5.8	1.11	.297	3.02	63	2.90	68	7.93	38.8
13	Joe Saunders J. Saunders	17	2008	LAA	7	.708	31	31	3.41	103	1	0	0	198.0	187	75	82	21	53	6	0	2	807	3	4.68	2.41	1.94	0.95	12.8	6.6	1.21	.266	3.73	79	4.36	102	8.50	-1.9
14	Edinson Volquez E. Volquez	17	2008	CIN	6	.739	33	32	3.21	206	0	0	0	196.0	167	70	82	14	93	14	1	5	838	10	9.46	4.27	2.22	0.64	24.6	11.1	1.33	.299	3.77	73	3.59	81	7.67	18.3
15	Chad Billingsley C. Billingsley	16	2008	LAD	10	.615	35	32	3.14	201	1	1	0	200.2	188	70	76	14	80	8	1	6	859	10	9.01	3.59	2.51	0.63	23.4	9.3	1.34	.313	3.41	75	3.34	78	8.43	20.8
16	Aaron Cook A. Cook	16	2008	COL	9	.640	32	32	3.96	96	2	1	0	211.1	236	93	102	13	48	4	0	2	886	6	4.09	2.04	2.00	0.55	10.8	5.4	1.34	.308	4.34	86	3.75	84	10.05	16.9
17	Dan Haren D. Haren	16	2008	ARI	8	.667	33	33	3.33	206	1	1	0	216.0	204	80	86	19	40	6	0	4	881	11	8.58	1.67	5.15	0.79	23.4	4.5	1.13	.303	3.58	74	3.00	68	8.50	33.2
18	Jon Lester J. Lester	16	2008	BOS	6	.727	33	33	3.21	152	2	2	0	210.1	202	75	78	14	66	10	0	1	874	3	6.50	2.82	2.30	0.60	17.4	7.6	1.27	.297	3.34	71	3.63	87	8.64	13.2
19	Jamie Moyer J. Moyer	16	2008	PHI	7	.696	33	33	3.71	123	0	0	0	196.1	199	81	85	20	62	11	0	4	841	3	5.64	2.84	1.98	0.92	14.6	7.4	1.33	.286	3.90	86	4.31	99	9.12	1.1
20	Ervin Santana E. Santana	16	2008	LAA	7	.696	32	32	3.49	214	2	1	0	219.0	198	85	89	23	47	8	0	2	897	5	8.79	1.93	4.55	0.95	23.9	5.2	1.12	.289	3.66	81	3.29	77	8.14	24.1
21	Johan Santana J. Santana	16	2008	NYM	7	.696	34	34	2.53	206	3	2	0	234.1	206	66	74	23	63	4	0	5	964	9	7.91	2.42	3.27	0.88	21.4	6.5	1.15	.274	2.84	61	3.50	82	7.91	20.2
22	Bronson Arroyo B. Arroyo	15	2008	CIN	11	.577	34	34	4.77	163	1	0	0	200.0	219	106	116	29	68	6	0	2	871	6	7.34	3.06	2.40	1.31	18.7	7.8	1.44	.314	5.22	108	4.49	101	9.86	-0.7
23	Mark Buehrle M. Buehrle	15	2008	CWS	12	.556	34	34	3.79	140	1	0	0	218.2	240	92	106	22	52	5	0	4	918	4	5.76	2.14	2.69	0.91	15.3	5.7	1.34	.312	4.36	84	3.93	87	9.88	14.3
24	Kyle Lohse K. Lohse	15	2008	STL	6	.714	33	33	3.78	119	0	0	0	200.0	211	84	88	18	49	3	0	3	839	5	5.36	2.21	2.43	0.81	14.2	5.8	1.30	.297	3.96	91	3.88	92	9.50	7.6
25	Ricky Nolasco R. Nolasco	15	2008	FLA	8	.652	34	32	3.52	186	1	1	0	212.1	192	83	88	28	42	6	0	6	868	1	7.88	1.78	4.43	1.19	21.4	4.8	1.10	.271	3.73	81	3.76	88	8.14	12