Since 1965, Greg Maddux has won the most games, with 355 wins.

Interpreted as:

pitcher with most regular-season wins from 1965

	NAME	W	L	W%	G	GS	ERA	SO	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Greg Maddux G. Maddux	355	227	.610	744	740	3.16	3,371	109	35	0	5008.1	4,726	1,756	1,981	353	999	137	3	177	20,421	70	6.06	1.80	3.37	0.63	16.5	4.9	1.14	.281	3.56	76	3.25	78	8.49	519.5
2	Roger Clemens R. Clemens	354	184	.658	709	707	3.12	4,672	118	46	0	4916.2	4,185	1,707	1,885	363	1,580	159	0	63	20,240	143	8.55	2.89	2.96	0.66	23.1	7.8	1.17	.284	3.45	70	3.08	71	7.66	680.4
3	Steve Carlton S. Carlton	329	244	.574	741	709	3.22	4,136	254	55	2	5217.2	4,672	1,864	2,130	414	1,833	53	13	150	21,683	183	7.13	3.16	2.26	0.71	19.1	8.5	1.25	.279	3.67	87	3.14	86	8.06	271.5
4	Nolan Ryan N. Ryan	324	292	.526	807	773	3.19	5,714	222	61	3	5386.0	3,923	1,911	2,178	321	2,795	158	13	78	22,575	277	9.55	4.67	2.04	0.54	25.3	12.4	1.25	.265	3.64	90	2.96	83	6.56	370.2
5	Don Sutton D. Sutton	324	256	.559	774	756	3.26	3,574	178	58	5	5282.1	4,692	1,914	2,104	472	1,343	82	12	102	21,631	112	6.09	2.29	2.66	0.80	16.5	6.2	1.14	.261	3.58	92	3.23	90	7.99	181.2
6	Phil Niekro P. Niekro	318	274	.537	854	716	3.35	3,334	245	45	29	5389.0	5,029	2,004	2,327	481	1,802	122	81	86	22,611	225	5.57	3.01	1.85	0.80	14.7	8.0	1.27	.270	3.89	86	3.61	95	8.40	117.3
7	Tom Seaver T. Seaver	311	205	.603	656	647	2.86	3,640	231	61	1	4783.0	3,971	1,521	1,674	380	1,390	76	6	116	19,369	126	6.85	2.62	2.62	0.72	18.8	7.2	1.12	.259	3.15	79	3.03	85	7.47	286.1
8	Tom Glavine T. Glavine	305	203	.600	682	682	3.54	2,607	56	25	0	4413.1	4,298	1,734	1,900	356	1,500	66	0	145	18,604	65	5.32	3.06	1.74	0.73	14.0	8.1	1.31	.280	3.87	86	3.94	94	8.76	120.1
9	Randy Johnson R. Johnson	303	166	.646	618	603	3.29	4,875	100	37	2	4135.1	3,346	1,513	1,703	411	1,497	190	7	37	17,067	109	10.61	3.26	3.26	0.89	28.6	8.8	1.17	.291	3.71	75	3.18	73	7.28	554.3
10	Gaylord Perry G. Perry	298	247	.547	689	660	3.09	3,307	297	51	4	5024.2	4,621	1,724	1,993	370	1,293	101	15	149	20,586	148	5.92	2.32	2.56	0.66	16.1	6.3	1.18	.274	3.57	85	3.05	85	8.28	305.4
11	Bert Blyleven B. Blyleven	287	250	.534	692	685	3.31	3,701	242	60	0	4970.0	4,632	1,830	2,029	430	1,322	155	3	71	20,491	114	6.70	2.39	2.80	0.78	18.1	6.5	1.20	.282	3.67	85	3.18	82	8.39	368.6
12	Tommy John T. John	286	220	.565	729	683	3.34	2,171	160	45	3	4595.2	4,663	1,703	1,954	291	1,218	98	21	97	19,189	181	4.25	2.39	1.78	0.57	11.3	6.3	1.28	.284	3.83	90	3.36	89	9.13	207.1
13	Fergie Jenkins F. Jenkins	284	226	.557	664	594	3.34	3,192	267	49	7	4500.2	4,142	1,669	1,853	484	997	84	37	116	18,400	62	6.38	1.99	3.20	0.97	17.3	5.4	1.14	.268	3.71	87	3.27	88	8.28	222.9
14	Mike Mussina M. Mussina	270	153	.638	537	536	3.68	2,813	57	23	0	3562.2	3,460	1,458	1,559	376	785	60	0	29	14,593	71	7.11	1.98	3.58	0.95	19.3	5.4	1.19	.292	3.94	82	3.57	79	8.74	372.8
15	Jamie Moyer J. Moyer	269	209	.563	696	638	4.25	2,441	33	10	0	4074.0	4,231	1,926	2,076	522	1,155	146	15	69	17,356	57	5.39	2.55	2.11	1.15	14.1	6.7	1.32	.283	4.59	97	4.46	102	9.35	-33.5
16	Jim Palmer J. Palmer	268	152	.638	558	521	2.86	2,212	211	53	4	3948.0	3,349	1,253	1,395	303	1,311	38	15	37	16,114	85	5.04	2.99	1.69	0.69	13.7	8.1	1.18	.249	3.18	80	3.50	95	7.63	83.2
17	Justin Verlander J. Verlander	262	152	.633	539	539	3.32	3,471	26	9	0	3483.1	2,960	1,284	1,389	364	977	117	0	27	14,239	97	8.97	2.52	3.55	0.94	24.4	6.9	1.13	.279	3.59	79	3.43	81	7.65	304.7
18	Andy Pettitte A. Pettitte	256	153	.626	531	521	3.85	2,448	26	4	0	3316.0	3,448	1,418	1,572	288	1,031	55	3	42	14,074	69	6.64	2.80	2.37	0.78	17.4	7.3	1.35	.308	4.27	86	3.73	83	9.36	282.1
19	Jack Morris J. Morris	254	186	.577	549	527	3.90	2,478	175	28	0	3824.0	3,567	1,657	1,815	389	1,390	58	10	99	16,120	206	5.83	3.27	1.78	0.92	15.4	8.6	1.30	.269	4.27	96	3.93	95	8.40	93
20	CC Sabathia	251	161	.609	561	560	3.74	3,093	38	12	0	3577.1	3,404	1,485	1,623	382	1,099	123	0	44	14,989	74	7.78	2.76	2.81	0.96	20.6	7.3	1.26	.294	4.08	87	3.77	87	8.56	223.7
21	Bartolo Colon B. Colon	247	188	.568	565	552	4.12	2,535	38	13	0	3461.2	3,593	1,584	1,719	439	948	64	2	47	14,655	45	6.59	2.46	2.67	1.14	17.3	6.5	1.31	.296	4.47	95	4.14	96	9.34	71.6
22	Dennis Martinez D. Martinez	245	193	.559	692	562	3.70	2,149	122	30	8	3999.2	3,897	1,643	1,835	372	1,165	122	51	71	16,754	83	4.84	2.62	1.84	0.84	12.8	7.0	1.27	.272	4.13	94	3.91	99	8.77	17
23	Frank Tanana F. Tanana	240	236	.504	638	616	3.66	2,773	143	34	1	4188.1	4,063	1,704	1,910	448	1,255	129	10	116	17,641	119	5.96	2.70	2.21	0.96	15.7	7.1	1.27	.277	4.10	94	3.78	96	8.73	66.4
24	David Wells D. Wells	239	157	.604	660	489	4.13	2,201	54	12	13	3439.0	3,635	1,578	1,702	407	719	83	65	65	14,413	101	5.76	1.88	3.06	1.07	15.3	5.0	1.27	.293	4.45	93	3.99	90	9.51	172.9
25	Jim Kaat J. Kaat	228	178	.562	740	489	3.39	1,863	136	24	15	3584.1	3,708	1,349	1,583	304	793	68	93	102	15,016	84	4.68	1.99	2.35	0.76	12.4	5.3	1.26	.284	3.97	93	3.35	91	9.31	129.5