
| NAME | IP | G | W | L | W% | GS | ERA | SO | CG | SHO | SV | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | ERA- | FIP | FIP- | H/9 | PRAA | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | M. Mussina | 2200.1 | 343 | 165 | 104 | .613 | 342 | 3.80 | 1,835 | 26 | 11 | 0 | 2,197 | 928 | 1,001 | 232 | 457 | 46 | 0 | 17 | 9,056 | 47 | 7.51 | 1.87 | 4.02 | 0.95 | 20.3 | 5.0 | 1.21 | .303 | 4.09 | 84 | 3.47 | 77 | 8.99 | 252.9 | |
| 2 | T. Wakefield | 2103.0 | 431 | 133 | 114 | .538 | 300 | 4.40 | 1,459 | 9 | 0 | 22 | 2,021 | 1,029 | 1,144 | 273 | 767 | 126 | 59 | 21 | 9,051 | 78 | 6.24 | 3.28 | 1.90 | 1.17 | 16.1 | 8.5 | 1.33 | .272 | 4.90 | 94 | 4.66 | 107 | 8.65 | -72.5 | |
| 3 | M. Buehrle | 2061.0 | 326 | 135 | 97 | .582 | 301 | 3.80 | 1,188 | 24 | 8 | 0 | 2,143 | 871 | 973 | 236 | 470 | 52 | 6 | 35 | 8,562 | 17 | 5.19 | 2.05 | 2.53 | 1.03 | 13.9 | 5.5 | 1.27 | .288 | 4.25 | 82 | 4.16 | 90 | 9.36 | 106 | |
| 4 | R. Halladay | 2046.2 | 313 | 148 | 76 | .661 | 287 | 3.43 | 1,495 | 49 | 15 | 1 | 1,997 | 780 | 870 | 172 | 455 | 56 | 6 | 22 | 8,433 | 43 | 6.57 | 2.00 | 3.29 | 0.76 | 17.7 | 5.4 | 1.20 | .292 | 3.83 | 74 | 3.46 | 76 | 8.78 | 235.2 | |
| 5 | K. Rogers | 1959.1 | 313 | 126 | 89 | .586 | 310 | 4.33 | 1,060 | 17 | 4 | 0 | 2,121 | 943 | 1,039 | 200 | 632 | 88 | 1 | 16 | 8,460 | 36 | 4.87 | 2.90 | 1.68 | 0.92 | 12.5 | 7.5 | 1.41 | .296 | 4.77 | 92 | 4.42 | 97 | 9.74 | 29.3 | |
| 6 | B. Colon | 1865.2 | 292 | 139 | 92 | .602 | 291 | 4.07 | 1,467 | 26 | 7 | 0 | 1,846 | 843 | 917 | 235 | 626 | 41 | 0 | 25 | 7,902 | 33 | 7.08 | 3.02 | 2.34 | 1.13 | 18.6 | 7.9 | 1.32 | .291 | 4.42 | 88 | 4.21 | 93 | 8.91 | 68.6 | |
| 7 | J. Washburn | 1863.2 | 312 | 107 | 109 | .495 | 300 | 4.10 | 1,103 | 9 | 4 | 1 | 1,855 | 848 | 900 | 240 | 569 | 65 | 4 | 21 | 7,889 | 30 | 5.33 | 2.75 | 1.94 | 1.16 | 14.0 | 7.2 | 1.30 | .273 | 4.35 | 93 | 4.59 | 104 | 8.96 | -38.6 | |
| 8 | J. Moyer | 1833.2 | 283 | 122 | 80 | .604 | 282 | 4.01 | 1,097 | 18 | 6 | 0 | 1,847 | 817 | 877 | 231 | 462 | 71 | 1 | 24 | 7,717 | 21 | 5.38 | 2.27 | 2.37 | 1.13 | 14.2 | 6.0 | 1.26 | .276 | 4.30 | 91 | 4.38 | 98 | 9.07 | 14.9 | |
| 9 | B. Radke | 1798.1 | 279 | 106 | 99 | .517 | 279 | 4.13 | 1,070 | 28 | 8 | 0 | 1,979 | 825 | 882 | 226 | 293 | 51 | 0 | 9 | 7,510 | 22 | 5.35 | 1.47 | 3.65 | 1.13 | 14.2 | 3.9 | 1.26 | .299 | 4.41 | 89 | 4.09 | 92 | 9.90 | 70.8 | |
| 10 | A. Pettitte | 1770.1 | 283 | 141 | 85 | .624 | 280 | 4.18 | 1,280 | 14 | 2 | 0 | 1,920 | 822 | 915 | 153 | 579 | 36 | 0 | 22 | 7,641 | 31 | 6.51 | 2.94 | 2.21 | 0.78 | 16.8 | 7.6 | 1.41 | .316 | 4.65 | 92 | 3.82 | 84 | 9.76 | 139.2 | |
| 11 | CC Sabathia | 1758.2 | 271 | 125 | 79 | .613 | 271 | 3.77 | 1,462 | 21 | 8 | 0 | 1,632 | 736 | 796 | 162 | 565 | 55 | 0 | 22 | 7,318 | 35 | 7.48 | 2.89 | 2.59 | 0.83 | 20.0 | 7.7 | 1.25 | .290 | 4.07 | 85 | 3.67 | 84 | 8.35 | 138.8 | |
| 12 | F. Garcia | 1714.2 | 264 | 120 | 76 | .612 | 263 | 4.02 | 1,251 | 12 | 4 | 0 | 1,651 | 766 | 810 | 198 | 547 | 52 | 0 | 27 | 7,242 | 71 | 6.57 | 2.87 | 2.29 | 1.04 | 17.3 | 7.6 | 1.28 | .280 | 4.25 | 90 | 4.14 | 92 | 8.67 | 70.8 | |
| 13 | J. Garland | 1625.1 | 278 | 106 | 89 | .544 | 255 | 4.47 | 851 | 9 | 6 | 1 | 1,719 | 807 | 886 | 205 | 532 | 47 | 9 | 20 | 6,945 | 34 | 4.71 | 2.95 | 1.60 | 1.14 | 12.3 | 7.7 | 1.38 | .285 | 4.91 | 97 | 4.74 | 103 | 9.52 | -18.8 | |
| 14 | S. Ponson | 1623.2 | 274 | 84 | 103 | .449 | 255 | 5.07 | 964 | 29 | 4 | 1 | 1,858 | 915 | 980 | 210 | 562 | 40 | 7 | 15 | 7,097 | 48 | 5.34 | 3.12 | 1.72 | 1.16 | 13.6 | 7.9 | 1.49 | .310 | 5.43 | 113 | 4.68 | 102 | 10.30 | -18.7 | |
| 15 | J. Lackey | 1501.0 | 234 | 102 | 71 | .590 | 233 | 3.81 | 1,201 | 14 | 8 | 0 | 1,519 | 636 | 702 | 151 | 441 | 73 | 0 | 19 | 6,371 | 83 | 7.20 | 2.64 | 2.72 | 0.91 | 18.9 | 6.9 | 1.31 | .304 | 4.21 | 86 | 3.82 | 87 | 9.11 | 92.3 | |
| 16 | K. Escobar | 1476.0 | 384 | 98 | 89 | .524 | 202 | 4.18 | 1,274 | 10 | 4 | 45 | 1,433 | 685 | 743 | 136 | 592 | 47 | 109 | 26 | 6,344 | 54 | 7.77 | 3.61 | 2.15 | 0.83 | 20.1 | 9.3 | 1.37 | .302 | 4.53 | 90 | 3.87 | 85 | 8.74 | 109.2 | |
| 17 | B. Zito | 1430.1 | 222 | 102 | 63 | .618 | 222 | 3.55 | 1,096 | 9 | 4 | 0 | 1,228 | 564 | 620 | 148 | 560 | 65 | 0 | 14 | 5,998 | 26 | 6.90 | 3.52 | 1.96 | 0.93 | 18.3 | 9.3 | 1.25 | .262 | 3.90 | 80 | 4.16 | 93 | 7.73 | 47.3 | |
| 18 | D. Wells | 1426.2 | 215 | 111 | 53 | .677 | 214 | 4.18 | 926 | 33 | 9 | 0 | 1,563 | 663 | 714 | 172 | 237 | 40 | 0 | 5 | 5,988 | 25 | 5.84 | 1.50 | 3.91 | 1.09 | 15.5 | 4.0 | 1.26 | .302 | 4.50 | 90 | 3.92 | 87 | 9.86 | 97.9 | |
| 19 | P. Martinez | 1383.2 | 203 | 117 | 37 | .760 | 201 | 2.52 | 1,683 | 22 | 8 | 0 | 1,044 | 387 | 428 | 103 | 309 | 77 | 1 | 5 | 5,498 | 30 | 10.95 | 2.01 | 5.45 | 0.67 | 30.6 | 5.6 | 0.98 | .283 | 2.78 | 53 | 2.44 | 55 | 6.79 | 316.2 | |
| 20 | A. Sele | 1374.0 | 234 | 99 | 71 | .582 | 229 | 4.67 | 843 | 11 | 9 | 0 | 1,555 | 713 | 768 | 149 | 478 | 66 | 1 | 25 | 6,056 | 30 | 5.52 | 3.13 | 1.76 | 0.98 | 13.9 | 7.9 | 1.48 | .311 | 5.03 | 102 | 4.44 | 98 | 10.19 | 14.8 | |
| 21 | G. Meche | 1370.2 | 238 | 84 | 78 | .519 | 234 | 4.43 | 1,009 | 6 | 3 | 0 | 1,376 | 675 | 730 | 167 | 556 | 27 | 2 | 10 | 5,910 | 37 | 6.63 | 3.65 | 1.81 | 1.10 | 17.1 | 9.4 | 1.41 | .291 | 4.79 | 100 | 4.49 | 102 | 9.04 | -15 | |
| 22 | R. Clemens | 1337.2 | 208 | 103 | 48 | .682 | 207 | 3.77 | 1,285 | 8 | 5 | 0 | 1,213 | 560 | 614 | 127 | 486 | 48 | 0 | 8 | 5,645 | 56 | 8.65 | 3.27 | 2.64 | 0.85 | 22.8 | 8.6 | 1.27 | .294 | 4.13 | 83 | 3.59 | 79 | 8.16 | 143 | |
| 23 | E. Loaiza | 1322.0 | 235 | 85 | 70 | .548 | 204 | 4.72 | 893 | 11 | 5 | 1 | 1,495 | 693 | 745 | 167 | 368 | 46 | 11 | 20 | 5,740 | 17 | 6.08 | 2.51 | 2.43 | 1.14 | 15.6 | 6.4 | 1.41 | .311 | 5.07 | 100 | 4.30 | 93 | 10.18 | 51.2 | |
| 24 | J. Johnson | 1313.0 | 232 | 55 | 98 | .359 | 219 | 5.00 | 783 | 6 | 1 | 0 | 1,468 | 729 | 803 | 173 | 485 | 54 | 3 | 22 | 5,801 | 62 | 5.37 | 3.32 | 1.61 | 1.19 | 13.5 | 8.4 | 1.49 | .301 | 5.50 | 112 | 4.80 | 106 | 10.06 | -42.6 | |
| 25 | J. Santana | 1308.2 | 251 | 93 | 44 | .679 | 175 | 3.22 | 1,381 | 6 | 4 | 1 | 1,068 | 468 | 500 | 144 | 364 | 27 | 23 | 2 | 5,281 | 55 | 9.50 | 2.50 | 3.79 | 0.99 | 26.2 | 6.9 | 1.09 | .275 | 3.44 | 71 | 3.30 | 76 | 7.34 | 154.5 | |