Kohei Arihara gave up the most runs in a game in 2022, with 11 runs against the Blue Jays on September 10, 2022.

Interpreted as:

player most runs allowed in a regular-season game 2022

	NAME	R	DATE	TM		OPP	DEC	GS	ERA	SO	CG	SHO	SV	IP	H	ER	HR	BB	HBP	GF	IBB	TBF	WP
1	Kohei Arihara K. Arihara	11	9/10/2022	TEX	vs	TOR	L	1	33.00	1	0	0	0	3.0	12	11	2	5	0	0	0	26	0
2	Miles Mikolas M. Mikolas	10	8/9/2022	STL	@	COL	L	1	33.75	2	0	0	0	2.2	14	10	1	0	0	0	0	22	0
3	Joe Ryan J. Ryan	10	7/29/2022	MIN	@	SDP	L	1	19.29	7	0	0	0	4.2	8	10	5	2	0	0	0	24	0
4	José Ureña J. Ureña	10	7/28/2022	COL	vs	LAD	L	1	21.00	2	0	0	0	3.0	8	7	0	3	0	0	0	22	1
5	Paul Blackburn P. Blackburn	10	7/24/2022	OAK	vs	TEX	L	1	20.77	5	0	0	0	4.1	10	10	2	2	2	0	0	26	0
6	Thomas Hatch T. Hatch	10	7/2/2022	TOR	vs	TBR	L	1	19.29	4	0	0	0	4.2	12	10	3	2	1	0	0	26	0
7	Jerad Eickhoff J. Eickhoff	10	6/22/2022	PIT	vs	CHC	L	1	20.77	4	0	0	0	4.1	10	10	2	1	3	0	0	27	0
8	Elvin Rodríguez E. Rodríguez	10	6/3/2022	DET	@	NYY	L	1	20.77	4	0	0	0	4.1	11	10	4	2	0	0	0	24	0
9	Dallas Keuchel D. Keuchel	10	4/20/2022	CWS	@	CLE	L	1	63.00	0	0	0	0	1.0	10	7	1	1	0	0	0	17	1
10	Davis Martin D. Martin	9	10/5/2022	CWS	vs	MIN	L	1	48.60	1	0	0	0	1.2	7	9	2	2	0	0	0	14	0
11	Erick Fedde E. Fedde	9	10/5/2022	WSH	@	NYM	L	1	34.71	1	0	0	0	2.1	9	9	2	2	0	0	0	18	0
12	Luis Patiño L. Patiño	9	9/11/2022	TBR	@	NYY	L	1	60.75	0	0	0	0	1.1	5	9	3	4	0	0	0	13	0
13	Germán Márquez G. Márquez	9	9/9/2022	COL	vs	ARI		1	20.25	2	0	0	0	4.0	7	9	2	3	1	0	0	22	0
14	Cole Irvin C. Irvin	9	9/6/2022	OAK	vs	ATL		1	17.36	4	0	0	0	4.2	9	9	1	4	0	0	0	25	0
15	José Ureña J. Ureña	9	8/24/2022	COL	vs	TEX	L	1	60.75	1	0	0	0	1.1	9	9	0	3	0	0	0	16	0
16	Kutter Crawford K. Crawford	9	8/19/2022	BOS	@	BAL	L	1	22.09	2	0	0	0	3.2	11	9	3	0	0	0	0	21	0
17	Chad Kuhl C. Kuhl	9	8/3/2022	COL	@	SDP	L	1	16.20	4	0	0	0	5.0	8	9	3	3	1	0	0	26	0
18	Sean Manaea S. Manaea	9	7/25/2022	SDP	@	DET	L	1	10.80	4	0	0	0	3.1	8	4	2	1	0	0	0	20	0
19	Nathan Eovaldi N. Eovaldi	9	7/22/2022	BOS	vs	TOR	L	1	30.38	3	0	0	0	2.2	8	9	1	2	0	0	0	18	0
20	Luke Weaver L. Weaver	9	6/18/2022	ARI	vs	MIN	L	1	22.09	5	0	0	0	3.2	10	9	1	1	0	0	0	22	0
21	Patrick Corbin P. Corbin	9	6/16/2022	WSH	vs	PHI	L	1	5.40	2	0	0	0	3.1	8	2	2	1	0	0	0	21	0
22	Marcus Stroman M. Stroman	9	6/3/2022	CHC	vs	STL	L	1	20.25	7	0	0	0	4.0	10	9	3	1	0	0	0	22	0
23	Austin Gomber A. Gomber	9	6/2/2022	COL	vs	ATL	L	1	16.20	5	0	0	0	5.0	10	9	2	2	0	0	0	27	1
24	Thomas Szapucki T. Szapucki	9	5/25/2022	NYM	@	SFG	L	1	60.75	2	0	0	0	1.1	7	9	4	3	0	0	0	13	0
25	Nathan Eovaldi N. Eovaldi	9	5/17/2022	BOS	vs	HOU	L	1	32.40	0	0	0	0	1.2	8	6	5	0	0	0	0	14	0