The Boston Red Sox have a run differential of 15 runs versus the Cubs all-time.

	TEAM	DATE	DIFF	TM		OPP	RESULT	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Red Sox	6/10/2005	-8	BOS	@	CHC	L 6-14	37	6	10	2	0	3	6	3	0	6	0	0	40	21	5	0	0	0	0	.270	.325	.568	.893
2	Red Sox	6/11/2005	-1	BOS	@	CHC	L 6-7	36	6	9	3	0	2	6	5	0	13	0	0	41	18	5	0	0	0	0	.250	.341	.500	.841
3	Red Sox	6/12/2005	7	BOS	@	CHC	W 8-1	42	8	17	2	1	4	8	3	1	8	0	0	46	33	7	0	0	0	1	.405	.457	.786	1.242
4	Red Sox	5/20/2011	10	BOS	vs	CHC	W 15-5	42	15	19	6	0	2	13	6	0	5	2	0	49	31	8	0	1	0	1	.452	.510	.738	1.248
5	Red Sox	5/21/2011	-6	BOS	vs	CHC	L 3-9	35	3	9	0	0	1	3	4	1	2	2	0	40	12	1	0	0	1	1	.257	.350	.343	.693
6	Red Sox	5/22/2011	4	BOS	vs	CHC	W 5-1	31	5	12	2	1	1	5	1	1	3	0	1	35	19	4	0	2	0	2	.387	.400	.613	1.013
7	Red Sox	6/15/2012	-3	BOS	@	CHC	L 0-3	35	0	6	0	0	0	0	3	0	4	4	0	38	6	0	0	0	0	0	.171	.237	.171	.408
8	Red Sox	6/16/2012	1	BOS	@	CHC	W 4-3	32	4	8	3	0	1	4	5	1	8	0	1	38	14	4	0	0	0	0	.250	.368	.438	.806
9	Red Sox	6/17/2012	3	BOS	@	CHC	W 7-4	36	7	12	2	0	1	7	3	0	7	2	1	41	17	3	1	1	1	1	.333	.375	.472	.847
10	Red Sox	6/30/2014	-2	BOS	vs	CHC	L 0-2	28	0	2	0	0	0	0	1	0	10	0	0	29	2	0	0	0	0	1	.071	.103	.071	.175
11	Red Sox	7/1/2014	-1	BOS	vs	CHC	L 1-2	33	1	8	1	0	0	1	5	0	5	0	1	38	9	1	0	0	1	0	.242	.342	.273	.615
12	Red Sox	7/2/2014	-7	BOS	vs	CHC	L 9-16	42	9	16	4	0	1	9	5	1	10	0	0	50	23	5	0	2	0	0	.381	.440	.548	.988
13	Red Sox	4/28/2017	1	BOS	vs	CHC	W 5-4	33	5	13	2	0	1	5	3	0	10	0	1	36	18	3	0	0	0	2	.394	.444	.545	.990
14	Red Sox	4/29/2017	-3	BOS	vs	CHC	L 4-7	34	4	10	1	1	2	4	1	0	8	0	0	36	19	4	0	1	0	1	.294	.306	.559	.864
15	Red Sox	4/30/2017	4	BOS	vs	CHC	W 6-2	29	6	6	0	0	1	3	5	0	9	0	0	34	9	1	0	0	0	1	.207	.324	.310	.634
16	Red Sox	7/1/2022	-1	BOS	@	CHC	L 5-6	36	5	11	1	0	1	5	2	0	9	0	0	38	15	2	0	0	0	2	.306	.342	.417	.759
17	Red Sox	7/2/2022	-2	BOS	@	CHC	L 1-3	30	1	5	3	0	0	0	2	0	8	0	1	32	8	3	0	0	0	1	.167	.219	.267	.485
18	Red Sox	7/3/2022	2	BOS	@	CHC	W 4-2	43	4	10	0	0	0	1	6	0	12	0	0	49	10	0	0	0	0	2	.233	.327	.233	.559
19	Red Sox	7/14/2023	5	BOS	@	CHC	W 8-3	39	8	13	1	0	6	8	1	0	10	1	0	41	32	7	0	1	0	0	.333	.341	.821	1.162
20	Red Sox	7/15/2023	-6	BOS	@	CHC	L 4-10	32	4	6	4	0	1	4	3	0	7	0	0	35	13	5	0	0	0	1	.188	.257	.406	.663
21	Red Sox	7/16/2023	6	BOS	@	CHC	W 11-5	40	11	13	2	1	3	10	3	0	8	0	1	43	26	6	0	0	0	0	.325	.372	.650	1.022
22	Red Sox	4/26/2024	-6	BOS	vs	CHC	L 1-7	34	1	7	1	0	1	1	2	0	9	0	0	36	11	2	0	0	0	1	.206	.250	.324	.574
23	Red Sox	4/27/2024	17	BOS	vs	CHC	W 17-0	43	17	21	6	0	2	17	2	2	6	1	0	49	33	8	1	1	0	0	.488	.521	.767	1.288
24	Red Sox	4/28/2024	1	BOS	vs	CHC	W 5-4	34	5	9	1	1	0	5	5	0	9	1	0	39	12	2	0	0	1	0	.265	.359	.353	.712
	Total		15					856	135	252	47	5	34	125	79	7	186	13	7	953	411	86	2	9	4	18	.294	.355	.480	.836