The Cincinnati Reds have a run differential of -48 runs against the White Sox all-time.

	TEAM	DATE	DIFF	TM		OPP	RESULT	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Reds	6/13/1997	-2	CIN	vs	CWS	L 1-3	32	1	7	2	0	0	1	3	0	3	0	1	36	9	2	1	0	0	0	.219	.286	.281	.567
2	Reds	6/14/1997	4	CIN	vs	CWS	W 5-1	32	5	9	3	0	1	4	3	0	6	2	0	36	15	4	1	0	1	1	.281	.343	.469	.812
3	Reds	6/15/1997	-8	CIN	vs	CWS	L 6-14	39	6	14	4	0	0	6	3	0	2	0	0	42	18	4	0	0	0	1	.359	.405	.462	.866
4	Reds	6/24/1998	-2	CIN	@	CWS	L 2-4	30	2	5	0	0	1	2	3	0	3	0	0	33	8	1	0	0	0	2	.167	.242	.267	.509
5	Reds	6/25/1998	2	CIN	@	CWS	W 7-5	34	7	9	2	0	1	7	4	0	8	2	0	40	14	3	2	0	1	1	.265	.342	.412	.754
6	Reds	6/5/2000	-1	CIN	vs	CWS	L 3-4	34	3	10	1	0	1	3	2	0	7	0	1	36	14	2	0	0	0	1	.294	.333	.412	.745
7	Reds	6/6/2000	-5	CIN	vs	CWS	L 12-17	35	12	12	3	0	2	11	8	0	3	0	0	43	21	5	0	0	0	4	.343	.465	.600	1.065
8	Reds	6/7/2000	-2	CIN	vs	CWS	L 4-6	35	4	8	1	1	1	4	3	1	11	2	1	39	14	3	0	0	1	0	.229	.308	.400	.708
9	Reds	6/12/2001	-5	CIN	@	CWS	L 0-5	34	0	9	2	0	0	0	2	0	7	1	1	36	11	2	0	0	0	1	.265	.306	.324	.629
10	Reds	6/13/2001	-2	CIN	@	CWS	L 2-4	34	2	6	3	0	1	2	0	1	5	0	0	35	12	4	0	0	0	0	.176	.200	.353	.553
11	Reds	6/14/2001	-2	CIN	@	CWS	L 5-7	33	5	9	0	0	0	5	2	0	6	2	0	37	9	0	1	1	0	1	.273	.306	.273	.578
12	Reds	6/16/2006	-8	CIN	vs	CWS	L 4-12	33	4	7	0	0	2	4	1	0	8	1	0	34	13	2	0	0	0	1	.212	.235	.394	.629
13	Reds	6/17/2006	-2	CIN	vs	CWS	L 6-8	36	6	9	2	0	1	6	3	0	16	2	0	39	14	3	0	0	1	0	.250	.308	.389	.697
14	Reds	6/18/2006	-7	CIN	vs	CWS	L 1-8	32	1	4	0	0	0	1	1	0	4	0	0	33	4	0	0	0	0	0	.125	.152	.125	.277
15	Reds	6/19/2009	1	CIN	vs	CWS	W 4-3	31	4	11	3	1	1	4	1	1	2	1	0	35	19	5	1	1	0	2	.355	.382	.613	.995
16	Reds	6/20/2009	-2	CIN	vs	CWS	L 8-10	39	8	14	2	0	2	6	4	0	9	5	1	44	22	4	0	1	0	0	.359	.409	.564	.973
17	Reds	6/21/2009	-3	CIN	vs	CWS	L 1-4	31	1	6	1	0	0	1	2	1	3	1	0	35	7	1	0	1	0	0	.194	.257	.226	.483
18	Reds	5/9/2015	6	CIN	@	CWS	W 10-4	36	10	13	2	0	1	10	8	2	7	3	0	48	18	3	1	1	0	0	.361	.489	.500	.989
19	Reds	5/9/2015	-6	CIN	@	CWS	L 2-8	29	2	6	0	0	0	2	6	0	11	1	0	35	6	0	0	0	0	2	.207	.343	.207	.550
20	Reds	5/10/2015	-1	CIN	@	CWS	L 3-4	34	3	10	1	1	0	3	5	0	6	0	1	39	13	2	0	0	1	2	.294	.385	.382	.767
21	Reds	7/2/2018	2	CIN	vs	CWS	W 5-3	31	5	7	3	0	1	5	7	0	5	0	0	39	13	4	0	1	0	0	.226	.359	.419	.778
22	Reds	7/3/2018	-4	CIN	vs	CWS	L 8-12	46	8	10	1	1	3	7	5	0	15	1	0	52	22	5	1	0	0	0	.217	.294	.478	.772
23	Reds	7/4/2018	3	CIN	vs	CWS	W 7-4	32	7	8	1	0	0	6	3	2	8	0	0	38	9	1	1	0	0	0	.250	.351	.281	.633
24	Reds	9/18/2020	6	CIN	vs	CWS	W 7-1	31	7	8	1	0	4	7	4	0	9	0	0	35	21	5	0	0	0	0	.258	.343	.677	1.020
25	Reds	9/19/2020	-5	CIN	vs	CWS	L 0-5	31	0	6	2	0	0	0	5	0	12	0	0	36	8	2	0	0	0	2	.194	.306	.258	.564
	Total		-48					1,297	173	316	64	6	40	167	145	17	293	38	9	1,480	512	110	10	11	7	34	.244	.325	.395	.720