The St. Louis Cardinals had their best record in a season against the Reds in 1981, with a record of 5-0.

Interpreted as:

st louis record in a regular season all-time record vs reds

	TEAM	REC	SEASON	W%	G	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Cardinals	5-0	1981	1.000	5	5	0	178	38	50	12	3	2	35	31	2	29	9	3	216	74	17	2	3	3	3	.281	.388	.416	.804
2	Cardinals	20-2	1931	.909	22	20	2	771	133	229	50	17	7	120	58	6	44	18		851	334	74	16				.297	.351	.433	.784
3	Cardinals	19-3	1930	.864	22	19	3	765	151	257	56	18	7	137	55	2	57	16		845	370	81	23				.336	.382	.484	.866
4	Cardinals	19-3	1929	.864	22	19	3	736	123	210	40	12	15	115	52	3	47	9		818	319	67	27				.285	.335	.433	.768
5	Cardinals	17-5	1949	.773	23	17	5	826	129	237	43	12	18	123	99	9	71	1		949	358	73	15			20	.287	.369	.433	.803
6	Cardinals	14-5	2004	.737	19	14	5	672	111	199	49	3	28	106	66	5	109	5	3	764	338	80	13	8	10	9	.296	.360	.503	.862
7	Cardinals	16-6	1934	.727	23	16	6	869	141	265	61	18	13	135	62	5	86	7		953	401	92	17				.305	.355	.461	.816
8	Cardinals	16-6	1932	.727	23	16	6	821	105	211	48	12	11	89	42	4	54	19		876	316	71	9				.257	.296	.385	.681
9	Cardinals	16-6	1911	.727	25	16	6	824	116	211	29	14	2		89	18	92	21		950	274	45	19				.256	.342	.333	.674
10	Cardinals	13-5	1967	.722	18	13	5	632	67	154	32	4	12	64	47	6	128	10	8	689	230	48	2	2	5	6	.244	.301	.364	.665
11	Cardinals	11-5	2005	.688	16	11	5	558	100	163	26	3	26	95	47	5	75	9	1	621	273	55	5	6	3	13	.292	.349	.489	.838
12	Cardinals	15-7	1953	.682	23	15	7	787	108	222	47	4	19	103	75	7	71	3	1	876	334	70	7			29	.282	.350	.424	.774
13	Cardinals	15-7	1950	.682	22	15	7	748	96	194	36	6	11	91	91	2	79	5		849	275	53	8			15	.259	.341	.368	.709
14	Cardinals	15-7	1942	.682	22	15	7	738	102	186	42	9	9	93	72	1	90	12		825	273	60	14			15	.252	.319	.370	.689
15	Cardinals	15-7	1937	.682	22	15	7	739	91	193	36	12	5	79	50	3	89	9		806	268	53	14				.261	.311	.363	.673
16	Cardinals	15-7	1933	.682	22	15	7	787	93	228	39	13	4	87	37	2	65	15		841	305	56	15				.290	.323	.388	.711
17	Cardinals	12-6	2010	.667	18	12	6	609	94	176	38	2	18	91	62	6	103	8	3	691	272	58	8	6	11	14	.289	.357	.447	.804
18	Cardinals	10-5	2008	.667	15	10	5	518	84	153	30	5	22	79	52	5	94	3	3	582	259	57	4	3	4	18	.295	.363	.500	.863
19	Cardinals	8-4	1991	.667	12	8	4	387	45	104	16	2	7	43	44	0	58	15	9	437	145	25	3	3	4	7	.269	.341	.375	.716
20	Cardinals	8-4	1987	.667	12	8	4	403	67	116	23	4	5	66	43	0	70	19	8	453	162	32	3	4	3	9	.288	.353	.402	.755
21	Cardinals	8-4	1984	.667	12	8	4	396	58	98	18	5	11	56	40	1	94	12	6	443	159	34	3	3	2	7	.247	.316	.402	.717
22	Cardinals	14-8	1960	.636	22	14	8	747	98	201	41	5	22	88	63	6	96	8	4	823	318	68	5	2	7	22	.269	.330	.426	.756
23	Cardinals	14-8	1954	.636	22	14	8	786	139	240	43	3	21	131	93	8	65	5	7	902	352	67	5	10		26	.305	.380	.448	.828
24	Cardinals	14-8	1951	.636	22	14	8	764	88	201	34	6	12	86	69	4	63	1	2	850	283	52	13			20	.263	.327	.370	.698
25	Cardinals	14-8	1947	.636	22	14	8	780	132	211	38	10	17	120	98	6	94	7		898	320	65	14			15	.271	.356	.410	.767