The Boston Red Sox scored the most runs by a team in a game in 2003, with 25 runs against the Florida Marlins on June 27, 2003.

Interpreted as:

team most runs in a regular-season game 2003

	TEAM	R	DATE	TM		OPP	RESULT	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Red Sox	25	6/27/2003	BOS	vs	FLA	W 25-8	46	28	8	1	3	25	7	1	7	0	0	57	47	12	0	3	0	1	.609	.632	1.022	1.653
2	Rockies	20	9/23/2003	COL	vs	ARI	W 20-9	43	17	3	0	4	19	5	2	5	0	0	51	32	7	0	1	1	1	.395	.471	.744	1.215
3	Marlins	20	7/1/2003	FLA	vs	ATL	W 20-1	49	25	7	1	3	20	4	0	7	0	0	54	43	11	0	1	1	0	.510	.537	.878	1.415
4	White Sox	19	9/27/2003	CWS	@	KCR	W 19-3	48	21	7	0	0	17	5	1	8	1	1	55	28	7	0	1	0	0	.438	.491	.583	1.074
5	Phillies	18	9/9/2003	PHI	@	ATL	W 18-5	40	14	2	0	3	18	9	2	4	0	0	52	25	5	0	1	0	0	.350	.481	.625	1.106
6	Astros	18	8/26/2003	HOU	vs	LAD	W 18-4	40	17	5	1	2	17	9	0	8	2	0	49	30	8	0	0	0	1	.425	.531	.750	1.281
7	Blue Jays	18	5/16/2003	TOR	@	KCR	W 18-1	48	22	4	0	1	15	5	2	9	0	0	56	29	5	0	1	0	0	.458	.518	.604	1.122
8	Twins	18	5/16/2003	MIN	vs	CWS	W 18-3	43	20	4	0	4	18	4	0	4	0	0	48	36	8	1	0	0	0	.465	.511	.837	1.348
9	Athletics	17	8/24/2003	OAK	@	TOR	W 17-2	46	19	3	1	4	16	5	0	7	0	0	52	36	8	1	0	2	0	.413	.471	.783	1.253
10	Rangers	17	5/11/2003	TEX	vs	CLE	W 17-10	42	20	3	0	3	16	3	1	5	1	0	46	32	6	0	0	0	2	.476	.522	.762	1.284
11	Marlins	17	4/5/2003	FLA	@	ATL	W 17-1	50	23	5	1	3	16	3	1	9	2	0	54	39	9	0	0	2	2	.460	.500	.780	1.280
12	Diamondbacks	16	9/13/2003	ARI	vs	COL	W 16-6	40	15	5	0	2	15	7	0	6	1	0	48	26	7	0	1	1	0	.375	.458	.650	1.108
13	Rockies	16	8/3/2003	COL	@	PIT	W 16-4	51	24	7	0	4	16	3	0	11	2	0	54	43	11	0	0	0	0	.471	.500	.843	1.343
14	Cubs	16	7/20/2003	CHC	@	FLA	W 16-2	47	20	9	0	2	16	5	0	8	1	0	52	35	11	0	0	0	1	.426	.481	.745	1.225
15	Twins	16	6/19/2003	MIN	@	KCR	W 16-2	50	23	5	0	3	16	4	0	3	1	0	54	37	8	0	0	0	0	.460	.500	.740	1.240
16	Yankees	16	5/8/2003	NYY	@	SEA	W 16-5	43	17	3	1	2	15	3	1	2	0	0	48	28	6	0	1	0	0	.395	.438	.651	1.089
17	Rangers	16	4/29/2003	TEX	@	TOR	W 16-11	43	17	4	0	6	16	5	1	11	0	0	49	39	10	0	0	1	0	.395	.469	.907	1.376
18	Rangers	16	4/24/2003	TEX	vs	BOS	W 16-5	43	19	4	3	2	14	6	0	5	1	0	50	35	9	0	1	0	0	.442	.500	.814	1.314
19	Dodgers	16	4/20/2003	LAD	vs	SFG	W 16-4	40	18	5	0	1	16	5	0	6	0	0	47	26	6	1	1	0	0	.450	.500	.650	1.150
20	Cubs	16	4/17/2003	CHC	vs	CIN	W 16-3	38	16	4	1	4	16	9	0	4	0	0	47	34	9	0	0	0	2	.421	.532	.895	1.427
21	Phillies	16	4/9/2003	PHI	vs	ATL	W 16-2	43	18	3	0	4	15	6	0	11	1	0	50	33	7	1	0	1	0	.419	.490	.767	1.257
22	Phillies	16	4/5/2003	PHI	vs	PIT	W 16-1	43	19	6	0	2	16	5	1	5	0	0	50	31	8	1	0	1	0	.442	.510	.721	1.231
23	Tigers	15	9/23/2003	DET	@	KCR	W 15-6	42	18	4	0	3	14	6	2	8	1	0	53	31	7	1	2	0	1	.429	.500	.738	1.238
24	Yankees	15	9/10/2003	NYY	vs	DET	W 15-5	37	12	1	0	4	15	7	2	9	1	0	46	25	5	0	0	0	2	.324	.457	.676	1.132
25	White Sox	15	7/30/2003	CWS	@	KCR	W 15-4	45	19	2	0	6	15	6	1	4	1	0	53	39	8	0	1	0	1	.422	.491	.867	1.357